The Narrow Abdomen Ion Channel Complex Is Highly Stable and Persists from Development into Adult Stages to Promote Behavioral Rhythmicity

Fluorescence circadian imaging reveals a PDF-dependent transcriptional regulation of the Drosophila molecular clock

(2017) Virginie Sabado et al.   Scientific Reports

A novel homozygous splice site mutation in NALCN identified in siblings with cachexia, strabismus, severe intellectual disability, epilepsy and abnormal respiratory rhythm

(2016) Moran Gal et al.   European Journal of Medical Genetics

Persistence of RNAi-Mediated Knockdown in Drosophila Complicates Mosaic Analysis Yet Enables Highly Sensitive Lineage Tracing

(2016) Justin A. Bosch et al.   GENETICS

Synchronous Drosophila circadian pacemakers display nonsynchronous Ca2+ rhythms in vivo

(2016) X. Liang et al.   SCIENCE

BK channel inactivation gates daytime excitability in the circadian clock

(2016) Joshua P. Whitt et al.   Nature Communications

PDF Signaling Is an Integral Part of the Drosophila Circadian Molecular Oscillator

(2016) Shaul Mezan et al.   Cell Reports

Persistence of RNAi-Mediated Knockdown in Drosophila Complicates Mosaic Analysis Yet Enables Highly Sensitive Lineage Tracing

(2016) Justin A. Bosch et al.   GENETICS

De Novo Mutations in NALCN Cause a Syndrome Characterized by Congenital Contractures of the Limbs and Face, Hypotonia, and Developmental Delay

(2015) Jessica X. Chong et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Circadian Rhythms in Rho1 Activity Regulate Neuronal Plasticity and Network Hierarchy

(2015) Afroditi Petsakou et al.   CELL

A Conserved Bicycle Model for Circadian Clock Control of Membrane Excitability

(2015) Matthieu Flourakis et al.   CELL

Changing channels in pain and epilepsy: Exploiting ion channel gene therapy for disorders of neuronal hyperexcitability

(2015) Albert Snowball et al.   FEBS LETTERS

A Gain-of-Function Mutation inNALCNin a Child with Intellectual Disability, Ataxia, and Arthrogryposis

(2015) Kyota Aoyagi et al.   HUMAN MUTATION

The sodium leak channel, NALCN, in health and disease

(2014) Maud Cochet-Bissuel et al.   Frontiers in Cellular Neuroscience

Dual PDF Signaling Pathways Reset Clocks Via TIMELESS and Acutely Excite Target Neurons to Control Circadian Behavior

(2014) Adam Seluzicki et al.   PLOS BIOLOGY

PDF neuron firing phase-shifts key circadian activity neurons in Drosophila

(2014) Fang Guo et al.   eLife

Ancient association between cation leak channels and Mid1 proteins is conserved in fungi and animals

(2014) Alfredo Ghezzi et al.   Frontiers in Molecular Neuroscience

Identification of Long-Lived Proteins Reveals Exceptional Stability of Essential Cellular Structures

(2013) Brandon H. Toyama et al.   CELL

Circadian Pacemaking in Cells and Circuits of the Suprachiasmatic Nucleus

(2013) M. H. Hastings et al.   JOURNAL OF NEUROENDOCRINOLOGY

Emerging roles for post-transcriptional regulation in circadian clocks

(2013) Chunghun Lim et al.   NATURE NEUROSCIENCE

NLF-1 Delivers a Sodium Leak Channel to Regulate Neuronal Excitability and Modulate Rhythmic Locomotion

(2013) Lin Xie et al.   NEURON

Metabolic Turnover of Synaptic Proteins: Kinetics, Interdependencies and Implications for Synaptic Maintenance

(2013) Laurie D. Cohen et al.   PLoS One

UNC79 and UNC80, Putative Auxiliary Subunits of the NARROW ABDOMEN Ion Channel, Are Indispensable for Robust Circadian Locomotor Rhythms in Drosophila

(2013) Bridget C. Lear et al.   PLoS One

A Role for Drosophila ATX2 in Activation of PER Translation and Circadian Behavior

(2013) Y. Zhang et al.   SCIENCE

Molecular architecture of the mammalian circadian clock

(2013) Carrie L. Partch et al.   TRENDS IN CELL BIOLOGY

Central and Peripheral Circadian Clocks in Mammals

(2012) Jennifer A. Mohawk et al.   Annual Review of Neuroscience

A Mechanism for Circadian Control of Pacemaker Neuron Excitability

(2012) Marc Ruben et al.   JOURNAL OF BIOLOGICAL RHYTHMS

FlyAtlas: database of gene expression in the tissues of Drosophila melanogaster

(2012) S. W. Robinson et al.   NUCLEIC ACIDS RESEARCH

The Circadian Neuropeptide PDF Signals Preferentially through a Specific Adenylate Cyclase Isoform AC3 in M Pacemakers of Drosophila

(2012) Laura B. Duvall et al.   PLOS BIOLOGY

A Quantitative Spatial Proteomics Analysis of Proteome Turnover in Human Cells

(2011) François-Michel Boisvert et al.   MOLECULAR & CELLULAR PROTEOMICS

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

A genome-scale shRNA resource for transgenic RNAi in Drosophila

(2011) Jian-Quan Ni et al.   NATURE METHODS

Linking neural activity and molecular oscillations in the SCN

(2011) Christopher S. Colwell   NATURE REVIEWS NEUROSCIENCE

Sodium Leak Channels in Neuronal Excitability and Rhythmic Behaviors

(2011) Dejian Ren   NEURON

Animal clocks: a multitude of molecular mechanisms for circadian timekeeping

(2011) Mirko Pegoraro et al.   Wiley Interdisciplinary Reviews-RNA

Circadian Organization of Behavior and Physiology in Drosophila

(2010) Ravi Allada et al.   Annual Review of Physiology

Light and Temperature Control the Contribution of Specific DN1 Neurons to Drosophila Circadian Behavior

(2010) Yong Zhang et al.   CURRENT BIOLOGY

DN1p Circadian Neurons Coordinate Acute Light and PDF Inputs to Produce Robust Daily Behavior in Drosophila

(2010) Luoying Zhang et al.   CURRENT BIOLOGY

TheamnesiacGene Is Involved in the Regulation of Thermal Nociception inDrosophila melanogaster

(2009) Benjamin T. Aldrich et al.   JOURNAL OF NEUROGENETICS

The Neuropeptide PDF Acts Directly on Evening Pacemaker Neurons to Regulate Multiple Features of Circadian Behavior

(2009) Bridget C. Lear et al.   PLOS BIOLOGY