Article
Medicine, General & Internal
Eva Segelov, Christine Carrington, Sanchia Aranda, David Currow, John R. Zalcberg, Alexander G. Heriot, Linda Mileshkin, John Coutsouvelis, Jeremy L. Millar, Brian T. Collopy, Jon D. Emery, Phoebe Zhang, Simon Cooper, Carmel O'Kane, Janet Wale, Stephen J. Hancock, Anthony Sulkowski, John Bashford
Summary: Sponsored by the Australian Council on Healthcare Standards, a consensus-driven process using a modified Delphi methodology was conducted to determine a set of clinical indicators for cancer service provision in Australia. After a series of meetings and deliberations, a final set of 16 indicators was established by a multidisciplinary steering group and stakeholder group. This inaugural cancer clinical indicator set aims to drive continual improvement in cancer care provision across Australia and internationally.
MEDICAL JOURNAL OF AUSTRALIA
(2021)
Review
Orthopedics
Daniel Angel-Garcia, Ismael Martinez-Nicolas, Bianca Salmeri, Alizee Monot
Summary: This review aimed to identify quality indicators that can be used in hospital physical therapy units. A total of 178 clinical care indicators were identified, with a focus on process and outcome measures. However, there is a lack of indicators for efficiency, structure, equity, and accessibility.
Article
Oncology
Tianshu Liu, Yuxian Bai, Xiaoyan Lin, Wei Li, Jufeng Wang, Xiaochun Zhang, Hongming Pan, Chunmei Bai, Li Bai, Ying Cheng, Jingdong Zhang, Haijun Zhong, Yi Ba, Wenwei Hu, Ruihua Xu, Weijian Guo, Shukui Qin, Nong Yang, Jianwei Lu, Kohei Shitara, Ming Lei, Mingshun Li, Nicole Bao, Tian Chen, Lin Shen
Summary: Chinese patients in the global CheckMate 649 study showed improved efficacy and safety with nivolumab plus chemotherapy as first-line treatment for GC/GEJC/EAC.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Article
Medical Laboratory Technology
Julie L. V. Shaw, Saranya Arnoldo, Lori Beach, Ihssan Bouhtiauy, Davor Brinc, Miranda Brun, Christine Collier, Elie Kostantin, Angela W. S. Fung, Anna K. Fuzery, Yun Huang, Sukhbir Kaur, Michael Knauer, Lyne Labrecque, Felix Leung, Jennifer L. Shea, Vinita Thakur, Laurel Thorlacius, Allison A. Venner, Paul M. Yip, Vincent De Guire
Summary: Monitoring quality indicators is crucial for laboratory quality assurance. This study describes the process of establishing and monitoring quality indicators for point-of-care testing (POCT) glucose testing.
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
(2023)
Article
Oncology
Alexander Quaas, Aylin Pamuk, Sebastian Klein, Jennifer Quantius, Jan Rehkaemper, Atakan G. Barutcu, Josef Rueschoff, Thomas Zander, Florian Gebauer, Axel Hillmer, Reinhard Buettner, Wolfgang Schroeder, Christiane J. Bruns, Heike Loeser, Birgid Schoemig-Markiefka, Hakan Alakus
Summary: The study revealed a sex-specific prognostic effect of TANs in gastric and esophageal adenocarcinoma, with a favorable impact observed in the chromosomal instable subtype of gastric cancer and female patients. This suggests that TANs may play a significant role in the tumor microenvironment of solid tumors.
Article
Oncology
E. Griesshammer, S. Wesselmann, M. W. Beckmann, C. Dannecker, U. Wagner, N. T. Sibert, R. Armbrust, J. Sehouli
Summary: This study evaluates the results of medical-guideline-derived quality indicators for cervical cancer and ovarian cancer, examines the development of indicator implementation over time, and identifies improvement measures. The results show that process-organization indicators have a high degree of application and a significant impact on the quality of care. Treatment-procedures indicators reach a plateau where the guideline is known, and surgical interventions indicators fluctuate.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2023)
Article
Health Care Sciences & Services
Joachim Cohen, Kirsten Hermans, Charless Dupont, Lieve van den Block, Luc Deliens, Kathleen Leemans
Summary: This study evaluated the quality of palliative care in 36 Belgian palliative care teams and found large risk-adjusted variations between teams in multiple quality indicators. The results suggest the importance of repeated and standardized quality improvement evaluations to identify areas in palliative care delivery that need improvement and to allow teams to benchmark themselves against each other.
PALLIATIVE MEDICINE
(2021)
Article
Oncology
Citadel J. Cabasag, Melina Arnold, Marion Pineros, Eileen Morgan, James Brierley, Jim Hofferkamp, Sean Kehoe, John Butler, Oliver Bucher, Freddie Bray, Isabelle Soerjomataram, D. Maxwell Parkin
Summary: Cancer stage at diagnosis is crucial for managing individual patients and evaluating health care system effectiveness. International comparison of cancer survival by stage is challenging due to lack of standardized recording and variation in stage completeness across countries. Development of stage conversion algorithms and improvement of staging data completeness are recommended for valid international comparison.
INTERNATIONAL JOURNAL OF CANCER
(2021)
Article
Oncology
Chenchen Mao, Xiaodong Chen, Xiangwei Sun, Xiang Wang, Ce Zhu, Wenjing Chen, Xiangyang Xue, Xian Shen
Summary: This study compared the short- and long-term outcomes of gastric cancer patients with visceral obesity who underwent laparoscopic gastrectomy or open gastrectomy. The results showed that laparoscopic gastrectomy reduced overall complications and postoperative hospital stays, as well as improved long-term overall survival compared to open radical gastrectomy in patients with visceral obesity.
Article
Medicine, General & Internal
Joanna Huang, Wasek Faisal, Margaret Brand, Shantelle Smith, Marliese Alexander, Lisa Briggs, Matthew Conron, Mary Duffy, Thomas John, David Langton, Jacqueline Lesage, Michael MacManus, Paul Mitchell, Inger Olesen, Phillip Parente, Jennifer Philip, Evangeline Samuel, Javier Torres, Craig R. Underhill, John R. Zalcberg, Susan Harden, Rob Stirling
Summary: This study analyzed data from patients with small cell lung cancer (SCLC) in Victoria and found that rates of supportive care screening, multidisciplinary meeting evaluation, and palliative care referral could be improved. Establishing a national registry for SCLC-specific management and outcomes data could enhance the quality and safety of care.
MEDICAL JOURNAL OF AUSTRALIA
(2023)
Article
Public, Environmental & Occupational Health
Anita Andreano, Maria Grazia Valsecchi, Antonio Giampiero Russo, Salvatore Siena
Summary: A set of 34 indicators for guideline-concordant care in lung cancer was selected and evaluated by a multidisciplinary panel of clinicians. Out of 22 feasible indicators, 16 were retained after assessing criterion validity and were further evaluated for reliability. The developed set of indicators is now available for implementing and monitoring quality initiatives for lung cancer care.
ARCHIVES OF PUBLIC HEALTH
(2021)
Review
Oncology
Marta Maes-Carballo, Yolanda Gomez-Fandino, Ayla Reinoso-Hermida, Carlos Roberto Estrada-Lopez, Manuel Martin-Diaz, Khalid Saeed Khan, Aurora Bueno-Cavanillas
Summary: The study identified 89 QIs from 22 selected documents, covering various aspects of breast cancer care. Most countries have not established national clinical pathways or integrated health care processes for breast cancer care, leading to heterogeneity in QIs for evaluating care quality.
Article
Urology & Nephrology
Benjamin V. Stone, Jacob E. Tallman, Kelvin A. Moses
Summary: The study found that treatment of adrenocortical carcinoma at an academic center is associated with improved overall survival compared to community programs. Academic centers had more aggressive surgical treatment practices, and the survival benefit persisted even after controlling for treatment modality in multivariable analysis.
JOURNAL OF UROLOGY
(2021)
Review
Clinical Neurology
Anna Kristina Kraft, Klaus Berger
Summary: This review identified six quality indicators for the assessment of care for patients with MS, based on evidence from 6 sources and a total of 226 quality indicators. Out of these, 147 indicators were included in the assessment, and the six identified indicators describe five important characteristics of high-quality care for MS patients.
FRONTIERS IN NEUROLOGY
(2021)
Article
Oncology
Ali Guner, Minah Cho, Yoo-Min Kim, Jae-Ho Cheong, Woo Jin Hyung, Hyoung-Il Kim
Summary: This study found that the neutrophil count and albumin level one month after surgery are independent prognostic factors for long-term prognosis in gastric cancer patients, helping to stratify patients into different prognostic groups.
FRONTIERS IN ONCOLOGY
(2021)
Article
Oncology
Chengqiang Li, Shengguang Zhao, Yuyan Zheng, Yichao Han, Xiaoyan Chen, Zenghui Cheng, Yuquan Wu, Xijia Feng, Weixiang Qi, Kai Chen, Jie Xiang, Jian Li, Toni Lerut, Hecheng Li
Summary: This study investigated the safety and efficacy of preoperative pembrolizumab combined with chemoradiotherapy in resectable oesophageal squamous cell carcinoma patients. The results showed that this treatment was safe and induced a pathological complete response in 55.6% of the tumors.
EUROPEAN JOURNAL OF CANCER
(2021)
Article
Surgery
Runsen Jin, Yuyan Zheng, Ye Yuan, Dingpei Han, Yuqin Cao, Yajie Zhang, Chengqiang Li, Jie Xiang, Zhengyuan Zhang, Zhenyi Niu, Toni Lerut, Jules Lin, Abbas E. Abbas, Alessandro Pardolesi, Takashi Suda, Dario Amore, Stefan Schraag, Clemens Aigner, Jian Li, Jiaming Che, Junbiao Hang, Jian Ren, Lianggang Zhu, Hecheng Li
Summary: This study compared the efficacy and perioperative outcomes of robotic-assisted lung cancer surgery (RAL) with video-assisted thoracic surgery (VAL) in patients with non-small cell lung cancer (NSCLC). The study found that both RAL and VAL are safe and feasible for NSCLC treatment, and RAL has an advantage in lymph node yield.
Review
Respiratory System
Toni Lerut, Dirk Van Raemdonck, Gilbert Massard
Summary: Founded in 1958, UEMS is the largest European medical organization representing over 1.5 million specialists of 43 specialties in 39 countries, with a primary goal to defend the interests of specialists and promote high quality care and continuous professional development. Its Section of Thoracic Surgery, established in 2013, focuses on harmonizing training and organization formats, and collaborates intensively with stakeholders to further shape the specialty.
JOURNAL OF THORACIC DISEASE
(2021)
Article
Surgery
Elena Prisciandaro, Herbert Decaluwe, Paul De Leyn, Willy Coosemans, Philippe Nafteux, Hans Van Veer, Lieven Depypere, Toni Lerut, Dirk Van Raemdonck, Laurens J. Ceulemans
Summary: The Klinkenbergh technique for bronchial stump suturing following lung resection is named after the Dutch surgeon Dr. Klinkenbergh, a pioneer in cardiothoracic surgery in Europe. This technique involves performing two running sutures to close the bronchus, reducing the occurrence of broncho-pleural fistulas. In our experience, less than 2% of patients developed post-operative broncho-pleural fistulas in the last 5 years.
ACTA CHIRURGICA BELGICA
(2021)
Article
Surgery
Yaxing Shen, Yiqun Zhang, Mengjiang He, Yong Fang, Shuai Wang, Pinghong Zhou, Lijie Tan, Toni Lerut
Summary: Transhiatal esophageal mobilization is a convenient surgical method that eliminates the need for thoracotomy. However, it carries some risks and requires technical expertise. Video-assisted or mediastinoscopic transhiatal esophagectomy has been introduced to improve the visualization of the procedure.
Article
Oncology
Jun Liu, Jingpei Li, Wanli Lin, Di Shao, Lieven Depypere, Zhifeng Zhang, Zhuoyi Li, Fei Cui, Zesen Du, Yuan Zeng, Shunjun Jiang, Ping He, Xia Gu, Huai Chen, Hai Zhang, Xiaowei Lin, Haoda Huang, Wenqiang Lv, Weiming Cai, Wenhua Liang, Hengrui Liang, Wenxi Jiang, Wei Wang, Ke Xu, Weipeng Cai, Kui Wu, Toni Lerut, Junhui Fu, Jianxing He
Summary: This study assessed the use of neoadjuvant camrelizumab plus chemotherapy in patients with resectable esophageal squamous cell carcinoma. The results showed that this treatment approach had promising efficacy and acceptable toxicity, providing an effective option for patients.
INTERNATIONAL JOURNAL OF CANCER
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Cecilia Pompili, Paula Ugalde Figueroa, Daniela Molena, Toni Lerut
INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY
(2022)
Article
Critical Care Medicine
Runsen Jin, Zhengyuan Zhang, Yuyan Zheng, Zhenyi Niu, Siying Sun, Yuqin Cao, Yajie Zhang, Abbas E. Abbas, Toni Lerut, Jules Lin, Hecheng Li
Summary: This study compared the impact of robot-assisted lobectomy (RAL) and video-assisted lobectomy (VAL) on quality of life in patients with resectable non-small cell lung cancer (NSCLC). The findings showed that both approaches had similar effects on health-related quality of life and postoperative pain up to 48 weeks after surgery, with some minor statistical differences at week 4.
Article
Gastroenterology & Hepatology
Duo Jiang, Xian-Ben Liu, Wen-Qun Xing, Pei-Nan Chen, Shao-Kang Feng, Sen Yan, Toni Lerut, Hai-Bo Sun
Summary: This study aimed to investigate the impact of the number of lymph nodes dissection (LND) on patients receiving neoadjuvant chemotherapy for esophageal squamous cell carcinoma. The results showed a non-linear relationship between LND and overall survival (OS) and disease-free survival (DFS). Moderate lymphadenectomy was beneficial for patients with nodal metastases, but more extended lymphadenectomy did not improve survival in patients without nodal metastases.
DISEASES OF THE ESOPHAGUS
(2023)
Review
Oncology
Toni Lerut
Summary: Since the first successful esophagectomy for cancer in 1913, significant advancements have been made in diagnosis, staging, and therapy. Improved imaging techniques, surgical procedures, perioperative management, and multidisciplinary collaboration have led to therapeutic options for more patients. Future innovations in imaging, molecular biology, genetics, artificial intelligence, machine learning, robotics, and nanotechnology will further enhance personalized treatment plans.
JOURNAL OF SURGICAL ONCOLOGY
(2023)
Editorial Material
Respiratory System
Alessandro Brunelli, Amerikos Argyriou, Hasan Batirel, Yolonda Colson, Gail Darling, Felix Fernandez, Michael Gooseman, Toni Lerut, Daniela Molena, Nuria Novoa, Isabelle Opitz, Kostas Papagiannopoulos, G. Alexander Patterson, Rene H. Petersen, Janette Rawlinson, Gaetano Rocco, Brendon M. Stiles, Javeria Tariq, Gonzalo Varela
JOURNAL OF THORACIC DISEASE
(2023)
Article
Cardiac & Cardiovascular Systems
Andreas Bouckaert, Johnny Moons, Toni Lerut, Willy Coosemans, Lieven Depypere, Hans Van Veer, Philippe Nafteux
Summary: A retrospective cohort study showed that primary surgery performed through transthoracic approach can yield comparable overall and disease-free survival after 5 years in locally advanced esophageal adenocarcinoma, with potentially fewer postoperative complications and shorter hospital and intensive care unit stay compared with neoadjuvant chemoradiotherapy followed by surgery.
ANNALS OF THORACIC SURGERY
(2023)
Article
Oncology
Stijn Vanstraelen, Lieven Depypere, Johnny Moons, Yannick Mandeville, Hans Van Veer, Toni Lerut, Willy Coosemans, Philippe Nafteux
Summary: Brain metastases after esophagectomy are rare and diagnostic uncertainty remains. Radiotherapy and advanced stage tumors are associated with the development of brain tumors after esophagectomy. Patients with brain tumors treated with curative intent have a significantly better median overall survival.
Article
Surgery
Kaiping Zhang, Jinlin Wu, Zhanhao Su, Yanfang Ma, Qianling Shi, Leandro Cardoso Barchi, Tanel Laisaar, Calvin S. H. Ng, Sebastien Gilbert, Xianzhuo Zhang, Tomaz Stupnik, Toni Lerut, Panpan Jiao, Hussein Elkhayat, Nuria M. Novoa, Robert Fruscio, Ryuichi Waseda, Rene Horsleben Petersen, Alfonso Fiorelli, Alan D. L. Sihoe, Diego Gonzalez-Rivas, Marco Scarci, Marcelo F. Jimenez, Grace S. Li, Xueqin Tang, Stephen D. Wang, Yaolong Chen
Summary: Surgical technique reporting checklist (SUPER) has been developed to improve the quality of reporting in surgical literature. This article provides an explanation and elaboration of each item in SUPER, along with multidisciplinary examples to help authors better understand and practice reporting their surgical research.
Review
Medicine, General & Internal
Yan Yan, Xijia Feng, Chengqiang Li, Toni Lerut, Hecheng Li
Summary: Esophageal cancer, with high incidence and poor prognosis, has two major histological types: squamous cell carcinoma and adenocarcinoma, which differ in their epidemiology and treatment options. Immunotherapy, particularly adjuvant immune checkpoint inhibitors (ICIs), has emerged as a potential treatment for resectable esophageal cancer. Recent clinical trials have shown promising results with ICIs for resectable esophageal cancer, although some concerns remain.
CHINESE MEDICAL JOURNAL
(2022)
