Co/NHPI-mediated aerobic oxygenation of benzylic C–H bonds in pharmaceutically relevant molecules
出版年份 2017 全文链接
标题
Co/NHPI-mediated aerobic oxygenation of benzylic C–H bonds in pharmaceutically relevant molecules
作者
关键词
-
出版物
Chemical Science
Volume 8, Issue 2, Pages 1282-1287
出版商
Royal Society of Chemistry (RSC)
发表日期
2016-10-07
DOI
10.1039/c6sc03831j
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Base metal-catalyzed benzylic oxidation of (aryl)(heteroaryl)methanes with molecular oxygen
- (2016) Hans Sterckx et al. Beilstein Journal of Organic Chemistry
- Copper-Catalyzed Aerobic Oxidation of Azinylmethanes for Access to Trifluoromethylazinylols
- (2016) Gang Zheng et al. CHINESE JOURNAL OF CHEMISTRY
- Scalable and sustainable electrochemical allylic C–H oxidation
- (2016) Evan J. Horn et al. NATURE
- Mechanism of the CuII-catalyzed benzylic oxygenation of (aryl)(heteroaryl)methanes with oxygen
- (2016) Hans Sterckx et al. Chemical Science
- Copper-catalysed aerobic oxidative esterification of N-heteroaryl methanes with alcohols
- (2016) Min Liu et al. Catalysis Science & Technology
- Copper catalysed direct amidation of methyl groups with N–H bonds
- (2015) Yao Huang et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Copper-catalyzed efficient direct amidation of 2-methylquinolines with amines
- (2015) Hao Xie et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Synergistic H4NI–AcOH Catalyzed Oxidation of the Csp3–H Bonds of Benzylpyridines with Molecular Oxygen
- (2015) Lanhui Ren et al. ORGANIC LETTERS
- Tandem Dehydrogenation/Oxidation/Oxidative Cyclization Approach to Wrightiadione and Its Derivatives
- (2015) Yujeong Jeong et al. ORGANIC LETTERS
- Cu-Catalyzed Aerobic Oxidative Esterification of Acetophenones with Alcohols to α-Ketoesters
- (2015) Xuezhao Xu et al. ORGANIC LETTERS
- Copper-catalyzed base-accelerated direct oxidation of C–H bond to synthesize benzils, isatins, and quinoxalines with molecular oxygen as terminal oxidant
- (2015) Jing-Wen Yu et al. TETRAHEDRON LETTERS
- Activated carbon for aerobic oxidation: Benign approach toward 2-benzoylbenzimidazoles and 2-benzoylbenzoxazoles synthesis
- (2015) Kai Bao et al. Scientific Reports
- TEMP and copper cocatalyzed oxygenation of ketones with molecular oxygen: chemoselective synthesis of α-ketoesters
- (2015) Xiaoqiang Huang et al. Organic Chemistry Frontiers
- Chloroacetate-Promoted Selective Oxidation of Heterobenzylic Methylenes under Copper Catalysis
- (2014) Jianming Liu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Bioactivation Potential of Thiophene-Containing Drugs
- (2014) Darja Gramec et al. CHEMICAL RESEARCH IN TOXICOLOGY
- A survey of solvent selection guides
- (2014) Denis Prat et al. GREEN CHEMISTRY
- Discovery of Clinical Candidate 1-(4-(3-(4-(1H-Benzo[d]imidazole-2-carbonyl)phenoxy)pyrazin-2-yl)piperidin-1-yl)ethanone (AMG 579), A Potent, Selective, and Efficacious Inhibitor of Phosphodiesterase 10A (PDE10A)
- (2014) Essa Hu et al. JOURNAL OF MEDICINAL CHEMISTRY
- Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals
- (2014) Edon Vitaku et al. JOURNAL OF MEDICINAL CHEMISTRY
- Copper-Catalyzed Aerobic Oxidative Amination of sp3C–H Bonds: Efficient Synthesis of 2-Hetarylquinazolin-4(3H)-ones
- (2014) Qiang Li et al. ORGANIC LETTERS
- Experimental Limiting Oxygen Concentrations for Nine Organic Solvents at Temperatures and Pressures Relevant to Aerobic Oxidations in the Pharmaceutical Industry
- (2014) Paul M. Osterberg et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- p-Xylene Oxidation to Terephthalic Acid: A Literature Review Oriented toward Process Optimization and Development
- (2013) Rogério A. F. Tomás et al. CHEMICAL REVIEWS
- Metal-free aerobic oxidation of benzazole derivatives
- (2013) Aurélie Dos Santos et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Sanofi’s Solvent Selection Guide: A Step Toward More Sustainable Processes
- (2013) Denis Prat et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- Copper-Catalyzed Oxidation of Deoxybenzoins to Benzils under Aerobic Conditions
- (2013) Antonella Goggiamani et al. SYNTHESIS-STUTTGART
- Homogeneous Liquid-Phase Oxidation of Ethylbenzene to Acetophenone in Continuous Flow Mode
- (2013) Bernhard Gutmann et al. ACS Catalysis
- Multiple Oxidative Dehydrogenative Functionalization of Arylacetaldehydes Using Molecular Oxygen as Oxidant Leading to 2-Oxo-acetamidines
- (2012) Chun Zhang et al. ADVANCED SYNTHESIS & CATALYSIS
- Synthesis of Oxazoles through Copper-Mediated Aerobic Oxidative Dehydrogenative Annulation and Oxygenation of Aldehydes and Amines
- (2012) Zejun Xu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Synthesis of Aryl(di)azinyl Ketones through Copper- and Iron-catalyzed Oxidation of the Methylene Group of Aryl(di)azinylmethanes
- (2012) Johan De Houwer et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Direct aerobic oxidation of 2-benzylpyridines in a gas–liquid continuous-flow regime using propylene carbonate as a solvent
- (2012) Bartholomäus Pieber et al. GREEN CHEMISTRY
- Copper-Catalyzed Aerobic Methyl/Methylene Oxygenation and C-H Formylation with a DABCO-DMSO System for the Synthesis of Carbonyl Indoles and Pyrroles
- (2012) Shunsuke Chiba et al. SYNTHESIS-STUTTGART
- Et3N-catalyzed oxidative dehydrogenative coupling of α-unsubstituted aldehydes and ketones with aryl diamines leading to quinoxalines using molecular oxygen as oxidant
- (2012) Chun Zhang et al. TETRAHEDRON
- Copper-Catalyzed Aerobic Oxidative Coupling of Aryl Acetaldehydes with Anilines Leading to α-Ketoamides
- (2011) Chun Zhang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Synthesis of α,β-Diketotriazoles by Aerobic Copper-Catalyzed Oxygenation with Triazole as an Intramolecular Assisting Group
- (2011) Christophe Menendez et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- Expanding GSK's solvent selection guide – embedding sustainability into solvent selection starting at medicinal chemistry
- (2011) Richard K. Henderson et al. GREEN CHEMISTRY
- Computational and structural studies on the complexation of cobalt(II) acetate by water and pyridine
- (2011) Henning Henschel et al. JOURNAL OF MOLECULAR STRUCTURE
- Synthesis of heteroaryl ketones via tandem reaction of 1,1-dibromoethenes
- (2011) Xuesen Fan et al. TETRAHEDRON
- Copper-catalyzed direct oxidative synthesis of α-ketoamides from aryl methyl ketones, amines, and molecular oxygen
- (2011) Feng-Tian Du et al. Chemical Science
- Development of safe and scalable continuous-flow methods for palladium-catalyzed aerobic oxidation reactions
- (2010) Xuan Ye et al. GREEN CHEMISTRY
- A novel and practical synthesis of 2-benzoylbenzothiazoles and 2-benzylbenzothiazoles
- (2010) Xuesen Fan et al. TETRAHEDRON LETTERS
- A Facile Aerobic Copper-Catalyzed α-Oxygenation of Aryl Thioacetamides: An Efficient Access to α-Keto Aryl Thioamides
- (2008) Firouz Moghaddam et al. SYNLETT
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started