Article
Chemistry, Multidisciplinary
Matthieu Starck, Jack D. Fradgley, Davide F. De Rosa, Andrei S. Batsanov, Maria Papa, Michael J. Taylor, Janet E. Lovett, Jacob C. Lutter, Matthew J. Allen, David Parker
Summary: A series of cationic and neutral p-Br and p-NO2 pyridine substituted Eu(III) and Gd(III) coordination complexes serve as versatile synthetic intermediates. The introduction of various substituents is made possible through nucleophilic aromatic substitution reactions, leading to the tuning of absorption and emission spectral properties in Eu(III) complexes. The p-substituent in Gd(III) complexes does not significantly affect EPR properties, making them suitable as EPR spin probes for biomolecules.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Article
Nanoscience & Nanotechnology
Alejandro Prieto-Castaneda, Siseth Martinez-Caballero, Antonia R. Agarrabeitia, Inmaculada Garcia-Moreno, Santiago de la Moya, Maria J. Ortiz, Juan A. Hermoso
Summary: The study introduces a ytterbium(III) complex as a phasing agent for de novo protein structure determination at approximately 1 A, offering high phasing power and high-quality electron density maps while maintaining crystallographic resolution. This agent presents a new possibility for X-ray crystallography of complex biomacromolecules.
ACS APPLIED BIO MATERIALS
(2021)
Article
Multidisciplinary Sciences
Waygen Thor, Yue Wu, Lei Wang, Yonghong Zhang, Peter A. Tanner, Ka-Leung Wong
Summary: The authors report a lanthanide-based compound that exhibits long-lived phosphorescence at low temperatures, showing potential applications in fields such as anti-counterfeiting and switches. Organolanthanide compounds typically have triplet state lifetimes up to tens of milliseconds, while this compound exhibits phosphorescence observable by the naked eye for up to 30 s at 77 K, providing insights into important photophysical processes.
NATURE COMMUNICATIONS
(2021)
Article
Biochemistry & Molecular Biology
Ying-Ying Pei, Jin-Tao Wang, Lin Yuan, Yi Luo, Xin-Yue Niu, Xing Rong, Lin Jin, Qing-Feng Li
Summary: This study reports a novel multicolor tunable, injectable, and biodegradable protein-based lanthanide luminescent hydrogel. The hydrogel was formed by denaturing BSA with urea and breaking the disulfide bonds in BSA with TCEP. The resulting crosslinked network was further enhanced by the reaction between lanthanide complexes and the remaining thiols in BSA. The hydrogel showed promising rheological properties, luminescent performances, injectability, and biodegradability. This work provides a feasible strategy for the design and fabrication of multifunctional protein luminescent hydrogels for potential applications in biomedicine, optoelectronics, and information technology.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Review
Chemistry, Inorganic & Nuclear
Yury A. Belousov, Andrei A. Drozdov, Ilya Taydakov, Fabio Marchetti, Riccardo Pettinari, Claudio Pettinari
Summary: The azole carboxylic acids provide a unique platform for driving the complex structures of lanthanide compounds, leading to materials with various desired properties. Understanding the coordination modes and synthesis of these compounds plays a crucial role in producing efficient advanced materials.
COORDINATION CHEMISTRY REVIEWS
(2021)
Review
Chemistry, Inorganic & Nuclear
Kui Xu, Xiaoji Xie, Li-Min Zheng
Summary: This review provides the latest advances in Ir-Ln complexes. The combination of Ir complexes and lanthanide ions in Ir-Ln complexes overcomes the limitations of lanthanide ions and enables the development of new multifunctional complexes for various applications.
COORDINATION CHEMISTRY REVIEWS
(2022)
Article
Spectroscopy
Sneha Wankar, Imran Khan, Umar Jan Pandit
Summary: This study aimed to synthesize europium complexes and their hybrids by embedding pure complex into silica and PMMA. The structure and photophysical properties of the complexes were elucidated using spectroscopic techniques and calculation methods, showing that incorporating the complex into PMMA can enhance stability and overcome the flaws of lanthanide complexes in terms of thermal stability and mechanical strength. The promising properties of the synthesized lanthanide hybrids are valuable for material research.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Crystallography
Ruijiang Fu, Wu-Pei Su, Hongxing He
Summary: This study reconstructed eight solved coiled-coil protein structures and demonstrated the direct phasing results. The retrieved phases had a mean phase error and the reconstructed model agreed with the deposited structure. The findings suggest that direct phasing is an efficient approach for constructing the protein envelope and solving the whole structure of coiled-coil proteins.
Article
Materials Science, Multidisciplinary
Kui Xu, Chen Lin, Ming-Feng Qin, Ze Yuan, Ye Tao, Song-Song Bao, Runfeng Chen, Xiaoji Xie, Li-Min Zheng
Summary: Amplification of near-infrared luminescence of lanthanide-doped nanoparticles can be achieved by a new type of iridium-based phosphonate complex as an antenna. The complex has a quasi-spherical structure and pendent phosphonic groups that resist aggregation-caused quenching and firmly anchor on nanoparticles. The complex can stably amplify the luminescence of lanthanide-doped nanoparticles up to 130 times, potentially due to short-range energy transfer from the complex to lanthanide ions. These findings provide a new fundamental approach to amplify the luminescence of lanthanide-doped nanoparticles and advance their applications.
ACS MATERIALS LETTERS
(2023)
Article
Materials Science, Multidisciplinary
Kui Xu, Chen Lin, Ming-Feng Qin, Ze Yuan, Ye Tao, Song-Song Bao, Runfeng Chen, Xiaoji Xie, Li-Min Zheng
Summary: Amplifying the photoluminescence of lanthanide-doped nanoparticles is important for practical applications. A new iridium-based phosphonate complex is discovered as an ideal antenna material to amplify the near-infrared luminescence of lanthanide-doped nanoparticles. The complex has a quasi-spherical structure and pendent phosphonic groups, which can resist aggregation-caused quenching and firmly anchor on nanoparticles. This complex can stably amplify the luminescence of lanthanide-doped nanoparticles up to 130 times by short-range energy transfer.
ACS MATERIALS LETTERS
(2023)
Article
Chemistry, Inorganic & Nuclear
Charlene Harriswangler, Laura Caneda-Martinez, Olivier Rousseaux, David Esteban-Gomez, Olivier Fougere, Rosa Pujales-Paradela, Laura Valencia, M. Isabel Fernandez, Nicolas Lepareur, Carlos Platas-Iglesias
Summary: We report a macrocyclic ligand (H3L6) that shows good coordination to metal ions and potential application as radiopharmaceuticals.
INORGANIC CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Tamara Boltersdorf, Felicity N. E. Gavins, Nicholas J. Long
Summary: The study demonstrates a switchable fluorescence effect through LRET technology with lanthanide, enhancing the brightness of lanthanide emission for cellular imaging applications. This strategy can be used to increase lanthanide emission rates for brighter optical probes.
Article
Chemistry, Physical
Sandrine Denis-Quanquin, Alessio Bartocci, Florence Szczepaniak, Francois Riobe, Olivier Maury, Elise Dumont, Nicolas Giraud
Summary: This study reveals the structural interplay between a tris-dipicolinate lanthanide probe and a decapeptide, emphasizing the necessity of large conformational sampling to reconcile characteristic time in NMR with molecular dynamics simulations. The research highlights the importance of a highly dynamic association process and opens the door for detailed mechanistic elucidation of lanthanide complex-peptide or lanthanide complex-protein interactions.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2021)
Article
Biochemistry & Molecular Biology
Jin-Tao Wang, Ying-Ying Pei, Cong-Hui Qu, Yi Wang, Xing Rong, Xin-Yue Niu, Jia Wang, Qing-Feng Li
Summary: A color-tunable, self-healing protein-based luminescent hydrogel was prepared, showing good biodegradability and biocompatibility, with potential applications in biomedical engineering and optical devices.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Chemistry, Physical
Qing-Fang Lin, Lu-Lu Ding, Zhong-Hao Xu, Qi-qi Wang, Ning-Fang Li, Yan Xu, Li-Li Liang
Summary: Three 3D coordination polymers were synthesized with lightweight ligands, showing good MCE for 1Gd and characteristic emissions of Eu-III and Tb-III ions for 2Tb and 3Eu.
JOURNAL OF MOLECULAR STRUCTURE
(2021)
Article
Chemistry, Multidisciplinary
Hao-Jung Chang, Mykhailo Bondar, Natalia Munera, Sylvain David, Olivier Maury, Gerard Berginc, Boris Le Guennic, Denis Jacquemin, Chantal Andraud, David J. Hagan, Eric W. Van Stryland
Summary: This study investigated the fast relaxation processes in the excited electronic states of functionalized aza-boron-dipyrromethene (aza-BODIPY) derivatives, including their linear photophysical, photochemical, and nonlinear optical properties. It was found that nonfluorescent derivatives exhibited optical gain in the near infrared range under femtosecond excitation. The study also discussed the role of bromine substituents in the molecular structures of these derivatives, and the excited states involved in electronic transitions were investigated using quantum-chemical TD-DFT calculations. The high two-photon absorption and excited-state absorption cross-sections, along with the measured photostability, suggest potential applications in photonics and optical limiting.
CHEMISTRY-A EUROPEAN JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Clotilde Philippe, Anh Thy Bui, Maxime Beau, Hugo Bloux, Francois Riobe, Olivier Mongin, Thierry Roisnel, Marie Cordier, Frederic Paul, Loic Lemiegre, Yann Trolez
Summary: In this study, 1,1,4,4-tetracyanobutadienes (TCBDs) carrying a wide variety of fluorophores were synthesized using a multi-step synthesis approach. The compounds were obtained from ynamides through a [2+2] cycloaddition/retroelectrocyclization reaction with tetracyanoethylene. The TCBDs exhibited remarkable emission properties across a wide range of wavelengths, from the visible region to the near-infrared (NIR) range. The quantum yields of these compounds in cyclohexane reached unexpectedly high values, up to 7.8%.
CHEMISTRY-A EUROPEAN JOURNAL
(2022)
Article
Chemistry, Medicinal
Carlo Andrea Mattei, Kais Dhbaibi, Bertrand Lefeuvre, Vincent Dorcet, Gilles Argouarch, Olivier Cador, Boris Le Guennic, Olivier Maury, Claudia Lalli, Stephan Guy, Amina Bensalah-Ledoux, Francois Riobe, Bruno Baguenard, Fabrice Pointillart
Summary: The interest in lanthanide circularly polarized luminescence (CPL) has been rapidly growing over the past 10 years. This study examined the correlation between chemical modifications in chiral ligands and the dissymmetry factor in CPL, focusing on four polymeric compounds of Eu(III) prepared with binaphtyl derivatives. The structures of the complexes were characterized in powder form and in solution, showing changes in CPL spectra and measurement of magnetic-dipole transition. Additionally, CPL measurements were conducted in the solid state for the polymer series.
Article
Biochemistry & Molecular Biology
Gabriella Collu, Tobias Bierig, Anna-Sophia Krebs, Sylvain Engilberge, Niveditha Varma, Ramon Guixa-Gonzalez, Timothy Sharpe, Xavier Deupi, Vincent Olieric, Emiliya Poghosyan, Roger M. Benoit
Summary: The article introduces a new protein nanotechnology tool, chimeric fusion proteins, which connect two protein domains using a single α-helical domain. These connections exhibit a degree of plasticity, allowing them to adapt to crystal contact opportunities. SAHs can be stably integrated into designed structural elements, enabling new possibilities for protein nanotechnology.
Article
Chemistry, Multidisciplinary
Eric Girard, Pedro Lopes, Michael Spoerner, Anne-Claire Dhaussy, Thierry Prange, Hans Robert Kalbitzer, Nathalie Colloc'h
Summary: In this study, the researchers used high pressure crystallography to investigate the allosteric transitions of Ras protein. They found that pressure can shift the equilibria between different conformational states, providing insight into the structural plasticity involved in Ras protein's allosteric equilibria.
Article
Chemistry, Multidisciplinary
Kais Dhbaibi, Maxime Grasser, Haiet Douib, Vincent Dorcet, Olivier Cador, Nicolas Vanthuyne, Francois Riobe, Olivier Maury, Stephan Guy, Amina Bensalah-Ledoux, Bruno Baguenard, Geert L. J. A. Rikken, Cyrille Train, Boris Le Guennic, Matteo Atzori, Fabrice Pointillart, Jeanne Crassous
Summary: The combination of physical properties sensitive to molecular chirality in a single system allows the observation of interesting phenomena such as magneto-chiral dichroism (MChD) and circularly polarized luminescence (CPL), which have potential applications in optical data readout and display technology. By coordinating a chiral organic chromophore to Yb(hfac)(3) units, homochiral one-dimensional coordination polymers of Yb-III were designed, which exhibit strong magnetic anisotropy and show single-molecule magnet behavior and room temperature magneto-chiral dichroism (MChD). Computational investigations support the correlation between MChD and the structure.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Inorganic & Nuclear
Pramila Selvanathan, Elsa Tufenkjian, Olivier Galangau, Thierry Roisnel, Francois Riobe, Olivier Maury, Lucie Norel, Stephane Rigaut
Summary: We present a bimetallic complex consisting of a ruthenium(II) bisacetylide complex with a photochromic dithienylethene (DTE) acetylide arm and a coordinating bipyridyl, in coordination with Yb(TTA)3 centers. The DTE isomerization is triggered by both UV light absorbed by the DTE unit and 450 nm excitation of the organometallic moiety. The redox behavior of the ruthenium(II) bisacetylide system is fully investigated, revealing a lack of stability of the DTE-closed oxidized state preventing effective redox luminescence switching while the photoswitching of ytterbium(III) NIR emission is fully operational.
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Inorganic & Nuclear
Amlia Godard, Laura Abad Galan, Jean Rouillon, Shaymaa Al Shehimy, Wassima Tajani, Charlotte Cave, Raluca Malacea-Kabbara, Yoann Rousselin, Pierre Le Gendre, Arnaud Fihey, Mohamed Bendellaa, Benoit Busser, Lucie Sancey, Boris Le Guennic, Christophe Bucher, Olivier Maury, Christine Goze, Ewen Bodio
Summary: Aza-boron-dipyrromethenes (Aza-BODIPYs) are a class of fluorophores with azadipyrromethene (aza-DIPY) ligand rigidified by a boron atom. Complexes of group 13 metals (aluminum and gallium) were synthesized and their properties were investigated. AzaGaDIPY and azaAlDIPY exhibited significant red-shifted fluorescence compared to aza-BODIPY, making them promising for optical medical imaging.
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Inorganic & Nuclear
Diamantoula Maniaki, Annika Sickinger, Leoni A. Barrios Moreno, David Aguila, Olivier Roubeau, Nicholas S. Settineri, Yannick Guyot, Francois Riobe, Olivier Maury, Laura Abad Galan, Guillem Aromi
Summary: We report the synthesis and structure of a pure [YbNdYb] coordination complex with short Yb...Nd distances, ideal for investigating intramolecular energy transfer from one Nd3+ ion to two Yb3+ centers. Selective allocation of both metal ions within the molecular structure is achieved by exploiting the difference in ionic radius and using two beta-diketone-type ligands. The efficiency of this process is confirmed by comparing emission and decay times of iso-absorbant solutions of 1, 2, and 3.
INORGANIC CHEMISTRY
(2023)
Article
Multidisciplinary Sciences
Bruno Baguenard, Amina Bensalah-Ledoux, Laure Guy, Francois Riobe, Olivier Maury, Stephan Guy
Summary: Circularly polarized luminescence (CPL) is a growing research field, and this paper presents a rigorous Mueller analysis method for a CPL spectrophotometer using polarizations space splitting. The authors demonstrate that accurate CPL spectra can be obtained quickly without the need of calibration, by combining spatial and temporal separation.
NATURE COMMUNICATIONS
(2023)
Article
Materials Science, Multidisciplinary
Silvia Mizzoni, Silvia Ruggieri, Annika Sickinger, Francois Riobe, Laure Guy, Margaux Roux, Guillaume Micouin, Akos Banyasz, Olivier Maury, Bruno Baguenard, Amina Bensalah-Ledoux, Stephan Guy, Alexei Grichine, Xuan-Nhi Nguyen, Andrea Cimarelli, Martina Sanadar, Andrea Melchior, Fabio Piccinelli
Summary: In this study, two pairs of cationic enantiomeric complexes were synthesized and characterized. They showed good sensitization of Sm(iii) and Eu(iii) luminescence and exhibited high CPL activity. In cell experiments, these complexes showed promise as nanoscale bioprobes.
JOURNAL OF MATERIALS CHEMISTRY C
(2023)
Article
Chemistry, Organic
Lucrezia Margherita Comparini, Andrea Menichetti, Lucilla Favero, Sebastiano Di Pietro, Fabrizio Badalassi, Per Ryberg, Mauro Pineschi
Summary: The stereoselective reduction of a diastereoisomeric mixture of benzo[g]octahydroquinolinium ion was examined in detail. A diastereoselective borohydride reduction in combination with an efficient deacylative enzymatic resolution of its β-aminoester precursor are the key steps for a stereoselective installation of the three chiral centers present in the (3S,4aS,10aR)-eutomer of the medicinal drug quinagolide. The obtained data paves the way for an easy and practical attainment of chiral 3-substituted octahydrobenzo[g]quinolines that are privileged structures in medicinal chemistry.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Chemistry, Inorganic & Nuclear
Haiet Douib, Jessica Flores Gonzalez, Saskia Speed, Vincent Montigaud, Bertrand Lefeuvre, Vincent Dorcet, Francois Riobe, Olivier Maury, Abdelkrim Gouasmia, Boris Le Guennic, Olivier Cador, Fabrice Pointillart
Summary: Complex reactions between various metal ions and ligands lead to the formation of heteroleptic compounds, some of which exhibit interesting magnetic properties or near-infrared luminescence under certain conditions.
DALTON TRANSACTIONS
(2022)
Article
Chemistry, Multidisciplinary
Jose Maria Andres Castan, C. Amruth, Pierre Josse, Laura Abad Galan, Pablo Simon Marques, Magali Allain, Olivier Maury, Tangui Le Bahers, Philippe Blanchard, Cyrille Monnereau, Gregory C. Welch, Clement Cabanetos
Summary: In this study, the N-annulation of a benzothioxanthene imide (BTI) derivative was demonstrated, resulting in the unprecedented thiochromenocarbazole imide (TCI) molecule. The impact of this chemical modification on molecular structure and optoelectronic properties was investigated using various experimental methods, highlighting the potential of TCI for applications in electroluminescent devices. Additionally, TCI-based dimers were successfully prepared and embedded in solution-processed organic light emitting devices (OLEDs) with improved solubility in non-halogenated solvents and good film forming capabilities.
MATERIALS CHEMISTRY FRONTIERS
(2022)
Article
Chemistry, Multidisciplinary
Alexander M. Prophet, Kritanjan Polley, Gary J. Van Berkel, David T. Limmer, Kevin R. Wilson
Summary: The oxidation kinetics of iodide by ozone at the air-water interface is studied in single microdroplets. Molecular simulations and kinetic modeling are used to understand the underlying multiphase mechanism.
Article
Chemistry, Multidisciplinary
Rong Zhang, Jiajing Lan, Fei Wang, Shumei Chen, Jian Zhang
Summary: By utilizing 1,1'-ferrocene dicarboxylic acid as a chelating and surface protection ligand, we have synthesized multi-nuclear indium oxide clusters with varying nuclear sizes, including heptanuclear and thirteen-nuclear clusters. These clusters possess labile coordination sites, allowing for structural modification and self-assembly, resulting in the formation of various cluster structures.
Article
Chemistry, Multidisciplinary
Hui Wang, Hui Liu, Mingsen Wang, Jiaheng Hou, Yongjun Li, Yuancheng Wang, Yingjie Zhao
Summary: Two supramolecular complexes were prepared using CBs and M1, and their single-crystal structures were analyzed by SCXRD. The unexpected 1:2 self-assembly structure between M1 and CB[8] was discovered for the first time. These complexes exhibit unique photophysical properties and provide valuable information about the structure and photophysical properties of supramolecular complexes.
Article
Chemistry, Multidisciplinary
Chang-Hee Lee, Sookil Park, Sanggil Kim, Ji Young Hyun, Hyun Soo Lee, Injae Shin
Summary: The epidermal growth factor receptor (EGFR) is a cell-surface glycoprotein involved in cell proliferation and tumor development. This study used a fluorescently labeled EGFR to investigate its time-dependent endocytosis in live cells and found that appended glycans affect EGFR internalization. Additionally, the study detected sialic acid residues attached to EGFR on the live cell surface using FRET-based imaging. This research provides valuable insights into the cellular functions of EGFR.
Article
Chemistry, Multidisciplinary
Subhankar Sahu, Lokesh Kumar, Sumita Das, Dipti Gupta, Ruchi Anand
Summary: This study proposes a strategy that combines organic electronics with biosensor scaffolds to create a compact device for monitoring environmental aromatic pollution. By coupling biosensing protein MopR with an organic electrochemical transistor (OECT), a sensor module capable of efficient detection of phenol was designed. Exclusive phenol detection with minimal loss of sensitivity could be achieved in complex pollutant mixtures and real environmental samples.
Review
Chemistry, Multidisciplinary
Changseok Lee, Hyung-Joon Kang, Sungwoo Hong
Summary: The formation of C-N bonds through hydroamination reactions catalyzed by nickel hydrides has been a topic of recent interest. This approach offers a way to efficiently transform a variety of alkene and alkyne substrates into compounds enriched with C-N bonds. The review provides a concise overview of the underlying reaction mechanisms and aims to stimulate further progress in NiH-catalytic techniques and catalyst design.
Article
Chemistry, Multidisciplinary
Yueci Wu, Lu-Lu Sun, Hai-Hao Han, Xiao-Peng He, Weiguo Cao, Tony D. James
Summary: Drug-induced liver injury (DILI) is a common cause of acute liver failure in the USA and Europe, but most cases can be recovered or prevented by discontinuing the offending drug. Recent research has found that peroxynitrite (ONOO-) can be used as a potential indicator for early diagnosis of DILI, and there is an urgent need to establish a method to detect and track peroxynitrite in DILI cases. In this study, a FRET-based nano fluorescent probe CD-N-I was developed, which showed high selectivity and sensitivity in detecting peroxynitrite. The probe successfully detected exogenous peroxynitrite in live cells and endogenous peroxynitrite in APAP-induced liver injury of HepG2 cells.
Article
Chemistry, Multidisciplinary
Dmitry L. Lipilin, Mikhail O. Zubkov, Mikhail D. Kosobokov, Alexander D. Dilman
Summary: This article describes a direct photocatalytic method for the thiolation of unprotected acids, which was previously challenging. By using a thionocarbonate reagent with an N-O bond, the efficient conversion of carboxylic acids to thiols is achieved.
Article
Chemistry, Multidisciplinary
Jason Malenfant, Lucille Kuster, Yohann Gagne, Kouassi Signo, Maxime Denis, Sylvain Canesi, Mathieu Frenette
Summary: Raman microscopy can reveal compound-specific vibrational fingerprints without sample preparation. The combination of efficient theoretical calculations and a user-friendly software can accurately predict peak positions and provide match scores to assist with structure determination.
Article
Chemistry, Multidisciplinary
Jayoh A. Hernandez, Paul S. Micus, Sean Alec Lois Sunga, Luca Mazzei, Stefano Ciurli, Gabriele Meloni
Summary: Essential trace metals play crucial roles in the survival and virulence of bacterial pathogens. Helicobacter pylori requires nickel for colonization and persistence in the stomach, and NixA is an essential nickel transporter in this process. This study characterizes the selectivity and electrogenic nature of NixA-mediated nickel transport.
Article
Chemistry, Multidisciplinary
Tarali Devi, Kuheli Dutta, Jennifer Deutscher, Stefan Mebs, Uwe Kuhlmann, Michael Haumann, Beatrice Cula, Holger Dau, Peter Hildebrandt, Kallol Ray
Summary: This study emphasizes the importance of subtle electronic changes and secondary interactions in the stability of biologically relevant metal-dioxygen intermediates. It also shows that the role of the chloride ligand in stabilizing the Fe-III-(OOBu)-Bu-t moiety can extend to other anions, including the thiolate ligand.
Article
Chemistry, Multidisciplinary
Jacqueline R. Santhouse, Jeremy M. G. Leung, Lillian T. Chong, W. Seth Horne
Summary: By studying the folding kinetics and mechanism of the BdpA sequence, researchers found that altering the backbone connectivity can affect protein folding. This suggests that protein mimetic chains have a significant degree of plasticity in transitioning between unfolded and folded states.
Article
Chemistry, Multidisciplinary
Divanshu Gupta, Ralf Einholz, Holger F. Bettinger
Summary: This study presents the first direct spectroscopic evidence of a cyclic seven-membered iminoborane. Compared to linear amino-iminoboranes, this cyclic iminoborane exhibits weakened bond strength and lower Lewis acidity value. The study suggests that the reduced ring strain of cyclic iminoborane prevents nitrogen fixation but allows facile (2 + 2) cycloaddition reaction with C2H4.
Article
Chemistry, Multidisciplinary
Renny Mathew, Aniruddha Mazumder, Praveen Kumar, Julie Matula, Sharmarke Mohamed, Petr Brazda, Mahesh Hariharan, Brijith Thomas
Summary: This study reveals the packing arrangement of partially disordered nitro-perylenediimide (NO2-PDI) using a synergistic approach that combines 3D ED, ssNMR, and DFT techniques. By overcoming these challenges, this methodology opens up new avenues for material characterization, driving exciting advancements in the field.
