Human Beta Defensin 2 Selectively Inhibits HIV-1 in Highly Permissive CCR6+CD4+ T Cells

The loss of CCR6+ and CD161+ CD4+ T-cell homeostasis contributes to disease progression in SIV-infected rhesus macaques

(2017) C S McGary et al.   Mucosal Immunology

Mucosal stromal fibroblasts markedly enhance HIV infection of CD4+ T cells

(2017) Jason A. Neidleman et al.   PLoS Pathogens

Persistence of integrated HIV DNA in CXCR3 + CCR6 + memory CD4+ T cells in HIV-infected individuals on antiretroviral therapy

(2016) Gabriela Khoury et al.   AIDS

Th17 Cells Are Preferentially Infected Very Early after Vaginal Transmission of SIV in Macaques

(2016) Daniel J. Stieh et al.   Cell Host & Microbe

Human Th17 Cells Lack HIV-Inhibitory RNases and Are Highly Permissive to Productive HIV Infection

(2016) Aaron Christensen-Quick et al.   JOURNAL OF VIROLOGY

New insights into the heterogeneity of Th17 subsets contributing to HIV-1 persistence during antiretroviral therapy

(2016) Vanessa Sue Wacleche et al.   Retrovirology

Sequential Dysfunction and Progressive Depletion of Candida albicans-Specific CD4 T Cell Response in HIV-1 Infection

(2016) Fengliang Liu et al.   PLoS Pathogens

Innate Immune Functions of a-Defensins in the Small Intestine

(2013) Charles L. Bevins   DIGESTIVE DISEASES

Antiviral Mechanisms of Human Defensins

(2013) Sarah S. Wilson et al.   JOURNAL OF MOLECULAR BIOLOGY

Preferential HIV Infection of CCR6+ Th17 Cells Is Associated with Higher Levels of Virus Receptor Expression and Lack of CCR5 Ligands

(2013) Y. Alvarez et al.   JOURNAL OF VIROLOGY

Simian Immunodeficiency Virus Infects Follicular Helper CD4 T Cells in Lymphoid Tissues during Pathogenic Infection of Pigtail Macaques

(2013) Y. Xu et al.   JOURNAL OF VIROLOGY

Plasticity of TH17 cells in Peyer's patches is responsible for the induction of T cell–dependent IgA responses

(2013) Keiji Hirota et al.   NATURE IMMUNOLOGY

Lower HIV Provirus Levels Are Associated with More APOBEC3G Protein in Blood Resting Memory CD4+ T Lymphocytes of Controllers In Vivo

(2013) MariaPia De Pasquale et al.   PLoS One

Beta-defensins activate macrophages and synergize in pro-inflammatory cytokine expression induced by TLR ligands

(2012) Nicola Barabas et al.   IMMUNOBIOLOGY

Expansion of HIV-specific T follicular helper cells in chronic HIV infection

(2012) Madelene Lindqvist et al.   JOURNAL OF CLINICAL INVESTIGATION

CD4 T follicular helper cell dynamics during SIV infection

(2012) Constantinos Petrovas et al.   JOURNAL OF CLINICAL INVESTIGATION

Th17 cells confer long-term adaptive immunity to oral mucosal Candida albicans infections

(2012) N Hernández-Santos et al.   Mucosal Immunology

APOBEC3G expression and hypermutation are inversely associated with human immunodeficiency virus type 1 (HIV-1) burden in vivo

(2012) Yordanka Kourteva et al.   VIROLOGY

The Yin and Yang of Human Beta-Defensins in Health and Disease

(2012) Aaron Weinberg et al.   Frontiers in Immunology

Sigmoid Th17 populations, the HIV latent reservoir, and microbial translocation in men on long-term antiretroviral therapy

(2011) Duncan Chege et al.   AIDS

Memory CCR6+CD4+ T Cells Are Preferential Targets for Productive HIV Type 1 Infection Regardless of Their Expression of Integrin  7

(2011) P. Monteiro et al.   JOURNAL OF IMMUNOLOGY

Human CD90 Identifies Th17/Tc17 T Cell Subsets That Are Depleted in HIV-Infected Patients

(2011) M. Guillot-Delost et al.   JOURNAL OF IMMUNOLOGY

CD4+ T Cells, Including Th17 and Cycling Subsets, Are Intact in the Gut Mucosa of HIV-1-Infected Long-Term Nonprogressors

(2011) E. J. Ciccone et al.   JOURNAL OF VIROLOGY

NFAT and IRF Proteins Regulate Transcription of the Anti-HIV Gene,APOBEC3G

(2010) Melissa A. Farrow et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human  -Defensin 2 and 3 and Their Mouse Orthologs Induce Chemotaxis through Interaction with CCR2

(2010) J. Rohrl et al.   JOURNAL OF IMMUNOLOGY

Susceptibility of Human Th17 Cells to Human Immunodeficiency Virus and Their Perturbation during Infection

(2010) Aimee El Hed et al.   JOURNAL OF INFECTIOUS DISEASES

Generation of functional human T-cell subsets with HLA-restricted immune responses in HLA class I expressing NOD/SCID/IL2r null humanized mice

(2010) L. D. Shultz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Th17 cell dynamics in HIV infection

(2010) Nichole R Klatt et al.   Current Opinion in HIV and AIDS

CCR6 ligands inhibit HIV by inducing APOBEC3G

(2009) M. K. Lafferty et al.   BLOOD

Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis

(2009) Heather R. Conti et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Peripheral Blood CCR4+CCR6+ and CXCR3+CCR6+ CD4+ T Cells Are Highly Permissive to HIV-1 Infection

(2009) A. Gosselin et al.   JOURNAL OF IMMUNOLOGY

Defensins in Viral Infections

(2009) Jian Ding et al.   Journal of Innate Immunity

Cytoplasmic APOBEC3G Restricts Incoming Vif-Positive Human Immunodeficiency Virus Type 1 and Increases Two-Long Terminal Repeat Circle Formation in Activated T-Helper-Subtype Cells

(2009) M. L. Vetter et al.   JOURNAL OF VIROLOGY

Glycerol monolaurate prevents mucosal SIV transmission

(2009) Qingsheng Li et al.   NATURE

Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections

(2008) J. M. Brenchley et al.   BLOOD

Interleukin-17 in host defence against bacterial, mycobacterial and fungal pathogens

(2008) Meredith M. Curtis et al.   IMMUNOLOGY

Human beta defensin 2 promotes intestinal wound healing in vitro

(2008) Jan-Michel Otte et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Altered balance between Th17 and Th1 cells at mucosal sites predicts AIDS progression in simian immunodeficiency virus-infected macaques

(2008) V Cecchinato et al.   Mucosal Immunology

Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis

(2008) Djahida Bouskra et al.   NATURE

Simian immunodeficiency virus–induced mucosal interleukin-17 deficiency promotes Salmonella dissemination from the gut

(2008) Manuela Raffatellu et al.   NATURE MEDICINE

‘Self-Protection’ of Individual CD4+ T Cells against R5 HIV-1 Infection by the Synthesis of Anti-Viral CCR5 Ligands

(2008) Yongjun Guan et al.   PLoS One

APOBEC3G Inhibits Elongation of HIV-1 Reverse Transcripts

(2008) Kate N. Bishop et al.   PLoS Pathogens

HIV-1 Vif promotes the formation of high molecular mass APOBEC3G complexes

(2007) Ritu Goila-Gaur et al.   VIROLOGY