CD4+CD25Hi FoxP3+ regulatory T cells in long-term cardiac xenotransplantation

Ex vivo-expanded baboon CD39 +  regulatory T cells prevent rejection of porcine islet xenografts in NOD-SCID IL-2rγ−/− mice reconstituted with baboon peripheral blood mononuclear cells

(2017) Dandan Huang et al.   XENOTRANSPLANTATION

Recombinant IL-33 prolongs leflunomide-mediated graft survival by reducing IFN-γ and expanding CD4+Foxp3+ T cells in concordant heart transplantation

(2016) Chen Dai et al.   LABORATORY INVESTIGATION

Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograft

(2016) Muhammad M. Mohiuddin et al.   Nature Communications

The role of all-trans retinoic acid in the biology of Foxp3+ regulatory T cells

(2015) Zhong-Min Liu et al.   Cellular & Molecular Immunology

Depletion of Foxp3+T Cells Abrogates Tolerance of Skin and Heart Allografts in Murine Mixed Chimeras Without the Loss of Mixed Chimerism

(2014) K. Shinoda et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Contribution of Regulatory T Cells and Effector T Cell Deletion in Tolerance Induction by Costimulation Blockade

(2014) B. Verbinnen et al.   JOURNAL OF IMMUNOLOGY

Genetically engineered pigs and target-specific immunomodulation provide significant graft survival and hope for clinical cardiac xenotransplantation

(2014) Muhammad M. Mohiuddin et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

An Anti-CD154 Domain Antibody Prolongs Graft Survival and Induces Foxp3+iTreg in the Absence and Presence of CTLA-4 Ig

(2013) D. F. Pinelli et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Foxp3+regulatory T cells are activated in spite of B7-CD28 and CD40-CD40L blockade

(2013) Isabel Vogel et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CTLA4Ig Inhibits Effector T Cells through Regulatory T Cells and TGF- 

(2013) C. M. Deppong et al.   JOURNAL OF IMMUNOLOGY

Outcome of Allogeneic Peripheral Blood Stem Cell Transplantation by Donor Graft CD3+/Tregs Ratio: A Single-Center Experience

(2012) Mario Delia et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Ex-vivo expanded baboon CD4+ CD25Hi Treg cells suppress baboon anti-pig T and B cell immune response

(2012) Avneesh K. Singh et al.   XENOTRANSPLANTATION

B-Cell Depletion Extends the Survival of GTKO.hCD46Tg Pig Heart Xenografts in Baboons for up to 8 Months

(2011) M. M. Mohiuddin et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics

(2010) C. G. Brunstein et al.   BLOOD

Cardiac allograft acceptance induced by blockade of CD40-CD40L costimulation is dependent on CD4+CD25+ regulatory T cells

(2010) Xiaofeng Jiang et al.   SURGERY

First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4+CD25+CD127− T regulatory cells

(2009) Piotr Trzonkowski et al.   CLINICAL IMMUNOLOGY

Regulatory T Cells Sequentially Migrate from Inflamed Tissues to Draining Lymph Nodes to Suppress the Alloimmune Response

(2009) Nan Zhang et al.   IMMUNITY

Regulatory T Cells and Immune Tolerance

(2008) Shimon Sakaguchi et al.   CELL