Schizophrenia and the neurodevelopmental continuum:evidence from genomics

Prevalence and architecture of de novo mutations in developmental disorders

(2017)   NATURE

Mental health of extremely low birth weight survivors: A systematic review and meta-analysis.

(2017) Karen J. Mathewson et al.   PSYCHOLOGICAL BULLETIN

Annual Research Review: The role of the environment in the developmental psychopathology of autism spectrum condition

(2016) William Mandy et al.   JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY

Schizophrenia

(2016) Michael J Owen et al.   LANCET

Exome sequencing for bipolar disorder points to roles of de novo loss-of-function and protein-altering mutations

(2016) M Kataoka et al.   MOLECULAR PSYCHIATRY

Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population

(2016) Elise B Robinson et al.   NATURE GENETICS

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

(2016) Christian R Marshall et al.   NATURE GENETICS

The implications of the shared genetics of psychiatric disorders

(2016) Michael C O'Donovan et al.   NATURE MEDICINE

Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders

(2016) Tarjinder Singh et al.   NATURE NEUROSCIENCE

Increased burden of ultra-rare protein-altering variants among 4,877 individuals with schizophrenia

(2016) Giulio Genovese et al.   NATURE NEUROSCIENCE

What can we learn from the high rates of schizophrenia in people with 22q11.2 deletion syndrome?

(2016) Michael J. Owen et al.   World Psychiatry

Defining the Effect of the 16p11.2 Duplication on Cognition, Behavior, and Medical Comorbidities

(2016) Debra D’Angelo et al.   JAMA Psychiatry

Exome Sequencing of Familial Bipolar Disorder

(2016) Fernando S. Goes et al.   JAMA Psychiatry

Analysis of Intellectual Disability Copy Number Variants for Association With Schizophrenia

(2016) Elliott Rees et al.   JAMA Psychiatry

Common alleles contribute to schizophrenia in CNV carriers

(2015) K E Tansey et al.   MOLECULAR PSYCHIATRY

Copy number variation in bipolar disorder

(2015) E K Green et al.   MOLECULAR PSYCHIATRY

Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis

(2015) Po-Ru Loh et al.   NATURE GENETICS

Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

(2015)   NATURE NEUROSCIENCE

Novel Findings from CNVs Implicate Inhibitory and Excitatory Signaling Complexes in Schizophrenia

(2015) Andrew J. Pocklington et al.   NEURON

Insights into Autism Spectrum Disorder Genomic Architecture and Biology from 71 Risk Loci

(2015) Stephan J. Sanders et al.   NEURON

Psychiatric disorders in child and adolescent offspring of patients with schizophrenia and bipolar disorder: A controlled study

(2015) Vanessa Sanchez-Gistau et al.   SCHIZOPHRENIA RESEARCH

What have we learned from the Psychiatric Genomics Consortium

(2015) Michael C. O'Donovan   World Psychiatry

De novo CNVs in bipolar affective disorder and schizophrenia

(2014) Lyudmila Georgieva et al.   HUMAN MOLECULAR GENETICS

Copy number variation in schizophrenia in Sweden

(2014) J P Szatkiewicz et al.   MOLECULAR PSYCHIATRY

Synaptic, transcriptional and chromatin genes disrupted in autism

(2014) Silvia De Rubeis et al.   NATURE

De novo mutations in schizophrenia implicate synaptic networks

(2014) Menachem Fromer et al.   NATURE

A polygenic burden of rare disruptive mutations in schizophrenia

(2014) Shaun M. Purcell et al.   NATURE

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

New Approaches to Psychiatric Diagnostic Classification

(2014) Michael J. Owen   NEURON

Genomic insights into the overlap between psychiatric disorders: implications for research and clinical practice

(2014) Joanne L Doherty et al.   Genome Medicine

The Penetrance of Copy Number Variations for Schizophrenia and Developmental Delay

(2013) George Kirov et al.   BIOLOGICAL PSYCHIATRY

Reduced burden of very large and rare CNVs in bipolar affective disorder

(2013) Detelina Grozeva et al.   BIPOLAR DISORDERS

Analysis of copy number variations at 15 schizophrenia-associated loci

(2013) Elliott Rees et al.   BRITISH JOURNAL OF PSYCHIATRY

CNV analysis in a large schizophrenia sample implicates deletions at 16p12.1 and SLC1A1 and duplications at 1p36.33 and CGNL1

(2013) E. Rees et al.   HUMAN MOLECULAR GENETICS

Clinical Significance of De Novo and Inherited Copy-Number Variation

(2013) Anneke T. Vulto-van Silfhout et al.   HUMAN MUTATION

Genetics of bipolar disorder

(2013) Nick Craddock et al.   LANCET

Developmental brain dysfunction: revival and expansion of old concepts based on new genetic evidence

(2013) Andres Moreno-De-Luca et al.   LANCET NEUROLOGY

Evidence that duplications of 22q11.2 protect against schizophrenia

(2013) E Rees et al.   MOLECULAR PSYCHIATRY

CNVs conferring risk of autism or schizophrenia affect cognition in controls

(2013) Hreinn Stefansson et al.   NATURE

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

(2013) Stephan Ripke et al.   NATURE GENETICS

Progress in the Genetics of Polygenic Brain Disorders: Significant New Challenges for Neurobiology

(2013) Steven A. McCarroll et al.   NEURON

Family History of Schizophrenia and Bipolar Disorder as Risk Factors for Autism

(2012) Patrick F. Sullivan et al.   ARCHIVES OF GENERAL PSYCHIATRY

Preterm Birth and Psychiatric Disorders in Young Adult Life

(2012) Chiara Nosarti et al.   ARCHIVES OF GENERAL PSYCHIATRY

CNVs: Harbingers of a Rare Variant Revolution in Psychiatric Genetics

(2012) Dheeraj Malhotra et al.   CELL

Practitioner Review: What have we learnt about the causes of ADHD?

(2012) Anita Thapar et al.   JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY

Range of genetic mutations associated with severe non-syndromic sporadic intellectual disability: an exome sequencing study

(2012) Anita Rauch et al.   LANCET

Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder

(2012) S E Bergen et al.   MOLECULAR PSYCHIATRY

Genetic architectures of psychiatric disorders: the emerging picture and its implications

(2012) Patrick F. Sullivan et al.   NATURE REVIEWS GENETICS

Fecundity of Patients With Schizophrenia, Autism, Bipolar Disorder, Depression, Anorexia Nervosa, or Substance Abuse vs Their Unaffected Siblings

(2012) Robert A. Power et al.   JAMA Psychiatry

Neurodevelopmental hypothesis of schizophrenia

(2011) Michael J. Owen et al.   BRITISH JOURNAL OF PSYCHIATRY

Genome-wide survey implicates the influence of copy number variants (CNVs) in the development of early-onset bipolar disorder

(2011) L Priebe et al.   MOLECULAR PSYCHIATRY

De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia

(2011) G Kirov et al.   MOLECULAR PSYCHIATRY

High Frequencies of De Novo CNVs in Bipolar Disorder and Schizophrenia

(2011) Dheeraj Malhotra et al.   NEURON

Relative Burden of Large CNVs on a Range of Neurodevelopmental Phenotypes

(2011) Santhosh Girirajan et al.   PLoS Genetics

Rare Copy Number VariantsA Point of Rarity in Genetic Risk for Bipolar Disorder and SchizophreniaRare Copy Number Variants

(2010) Detelina Grozeva   ARCHIVES OF GENERAL PSYCHIATRY

Birth Weight, Schizophrenia, and Adult Mental Disorder

(2010) Kathryn M. Abel et al.   ARCHIVES OF GENERAL PSYCHIATRY

The Kraepelinian dichotomy – going, going … but still not gone

(2010) Nick Craddock et al.   BRITISH JOURNAL OF PSYCHIATRY

Rare chromosomal deletions and duplications in attention-deficit hyperactivity disorder: a genome-wide analysis

(2010) Nigel M Williams et al.   LANCET

Strong synaptic transmission impact by copy number variations in schizophrenia

(2010) J. T. Glessner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study

(2009) Paul Lichtenstein et al.   LANCET

Rare structural variants in schizophrenia: one disorder, multiple mutations; one mutation, multiple disorders

(2009) Jonathan Sebat et al.   TRENDS IN GENETICS

Rare Structural Variants Disrupt Multiple Genes in Neurodevelopmental Pathways in Schizophrenia

(2008) T. Walsh et al.   SCIENCE