期刊
VIROLOGY
卷 509, 期 -, 页码 71-81出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.virol.2017.05.019
关键词
Rhabdoviridae; Nucleorhabdovirus; Virus-vector interactions; Hemipteran; Planthopper; Transcriptomics
类别
资金
- NSF [CNS-1006860, EPS-1006860, EPS-0919443]
- National Science Foundation CAREER Grant [IOS-0953786]
- Division Of Integrative Organismal Systems
- Direct For Biological Sciences [0953786] Funding Source: National Science Foundation
Maize mosaic virus (MMV) is a plant-pathogenic rhabdovirus that is transmitted by the corn planthopper, Peregrinus maidis, in a propagative manner. P. maidis supports long-term MMV infections with no negative effects on insect performance. To elucidate whole-body transcriptome responses to virus infection, RNA-Seq was used to examine differential gene expression of virus-infected adult insects, and libraries were prepared from replicated groups of virus-exposed insects and non-exposed insects. From the 68,003 de novo-assembled transcripts, 144 were differentially-expressed (DE) during viral infection with comparable numbers up- and down-regulated. DE transcripts with similarity to genes associated with transposable elements (i.e., RNA directed DNA polymerases) were enriched and may represent a mechanisim for modulating virus infection. Comparison of the P. maidis DE transcripts to published propagative virus-responsive transcript databases for two other hopper vectors revealed that 16% of the DE transcripts were shared across the three systems and may represent conserved responses to propagative viruses.
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