Genetic variation in the cholesterol transporter NPC1L1, ischaemic vascular disease, and gallstone disease

The ABCG5/8 Cholesterol Transporter and Myocardial Infarction Versus Gallstone Disease

(2014) Stefan Stender et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Liver-specific induction of Abcg5 and Abcg8 stimulates reverse cholesterol transport in response to ezetimibe treatment

(2014) Jessica B. Altemus et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Loss-of-Function Mutations in APOC3 and Risk of Ischemic Vascular Disease

(2014) Anders Berg Jørgensen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inactivating Mutations in NPC1L1 and Protection from Coronary Heart Disease

(2014)   NEW ENGLAND JOURNAL OF MEDICINE

Discovery and refinement of loci associated with lipid levels

(2013) Cristen J Willer et al.   NATURE GENETICS

Extreme Bilirubin Levels as a Causal Risk Factor for Symptomatic Gallstone Disease

(2013) Stefan Stender et al.   JAMA Internal Medicine

Effect of Long-Term Exposure to Lower Low-Density Lipoprotein Cholesterol Beginning Early in Life on the Risk of Coronary Heart Disease

(2012) Brian A. Ference et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Genetic Inhibition of CETP, Ischemic Vascular Disease and Mortality, and Possible Adverse Effects

(2012) Trine Holm Johannsen et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Remnant Cholesterol as a Causal Risk Factor for Ischemic Heart Disease

(2012) Anette Varbo et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial

(2011) Colin Baigent et al.   LANCET

New pathophysiological concepts underlying pathogenesis of pigment gallstones

(2011) Libor Vítek et al.   Clinics and Research in Hepatology and Gastroenterology

Sterol transporter adenosine triphosphate-binding cassette transporter G8, gallstones, and biliary cancer in 62,000 individuals from the general population

(2010) Stefan Stender et al.   HEPATOLOGY

PCSK9R46L, Low-Density Lipoprotein Cholesterol Levels, and Risk of Ischemic Heart Disease

(2010) Marianne Benn et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170 000 participants in 26 randomised trials

(2010)   LANCET

Ezetimibe prevents cholesterol gallstone formation in mice

(2010) Silvia Zúñiga et al.   LIVER INTERNATIONAL

Statin Use and the Risk of Cholecystectomy in Women

(2009) Chung–Jyi Tsai et al.   GASTROENTEROLOGY

Statin Use and Risk of Gallstone Disease Followed by Cholecystectomy

(2009) Michael Bodmer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The g.−762T>C polymorphism of the NPC1L1 gene is common in Chinese and contributes to a higher promoter activity and higher serum cholesterol levels

(2009) Chun-Wu Chen et al.   JOURNAL OF HUMAN GENETICS

Genetic variation at the NPC1L1 gene locus, plasma lipoproteins, and heart disease risk in the elderly

(2009) Eliana Polisecki et al.   JOURNAL OF LIPID RESEARCH

Extended-Release Niacin or Ezetimibe and Carotid Intima–Media Thickness

(2009) Allen J. Taylor et al.   NEW ENGLAND JOURNAL OF MEDICINE

An NPC1L1 gene promoter variant is associated with autosomal dominant hypercholesterolemia

(2009) B. Martín et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Rationale and design of IMPROVE-IT (IMProved Reduction of Outcomes: Vytorin Efficacy International Trial): Comparison of ezetimbe/simvastatin versus simvastatin monotherapy on cardiovascular outcomes in patients with acute coronary syndromes

(2008) Christopher P. Cannon et al.   AMERICAN HEART JOURNAL

Effect of Ezetimibe on the Prevention and Dissolution of Cholesterol Gallstones

(2008) Helen H. Wang et al.   GASTROENTEROLOGY

Effect of Statins Alone Versus Statins Plus Ezetimibe on Carotid Atherosclerosis in Type 2 Diabetes

(2008) Jerome L. Fleg et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Intensive Lipid Lowering with Simvastatin and Ezetimibe in Aortic Stenosis

(2008) Anne B. Rossebø et al.   NEW ENGLAND JOURNAL OF MEDICINE

Simvastatin with or without Ezetimibe in Familial Hypercholesterolemia

(2008) John J.P. Kastelein et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology

(2007) Debbie A. Lawlor et al.   STATISTICS IN MEDICINE