Article
Respiratory System
Xiucheng Liu, Hao Qin, Zheng Li, Yin Lv, Shoujie Feng, Wei Zhuang, Xiaoyu Quan, Chen Guo, Chang Chen, Hao Zhang
Summary: Inspiratory hyperoxia has special significance for the malignant phenotype of lung cancer cells, inhibiting metastasis and improving long-term survival by inducing significant intracellular metabolic changes.
EUROPEAN RESPIRATORY JOURNAL
(2022)
Article
Medicine, General & Internal
Ji-ling Guo, Han-bing Wang, Hong Wang, Yue Le, Jian He, Xue-qin Zheng, Zhi-hao Zhang, Guang-rong Duan
Summary: This paper presents 3 cases of air embolism associated with endoscopic medical procedures, highlighting the importance of early recognition and prompt hyperbaric oxygen therapy to prevent serious consequences.
Review
Emergency Medicine
Chiao-Zhu Li, Chiao-Ching Li, Meng-Chi Lin, Wei-Shih Tseng
Summary: Acute carbon monoxide (CO) poisoning can result in sudden hearing loss, which is a rare symptom. This study reports a case of a 42-year-old woman who developed acute hearing loss after exposure to high concentration of CO and achieved partial recovery with a combination of corticosteroid and hyperbaric oxygen therapy.
HONG KONG JOURNAL OF EMERGENCY MEDICINE
(2023)
Article
Medicine, General & Internal
Awni Alshurafa, Mohammed Alkhatib, Mohammad Abu-Tineh, Mohamed A. Yassin
Summary: Sickle cell leg ulcers (SCLUs) are chronic and painful complications of sickle cell disease, caused by skin vaso-occlusion, chronic inflammation, and endothelial dysfunction. Managing SCLUs is challenging and various treatments have been attempted, but there are no official recommendations for the best effective treatment. We report a successful case of a 34-year-old male patient with non-transfusion-dependent sickle cell disease, whose chronic left ankle ulcer was completely resolved with hyperbaric oxygen therapy.
FRONTIERS IN MEDICINE
(2023)
Article
Medicine, General & Internal
Awni Alshurafa, Mohammad Elhissi, Mohamed A. Yassin
Summary: Avascular necrosis (AVN) is a serious complication of sickle cell disease that requires challenging and controversial management. Early AVN can be treated conservatively, while advanced stages usually require surgery. Hyperbaric oxygen therapy can be used as an adjunctive treatment to control symptoms and improve the quality of life for AVN patients.
FRONTIERS IN MEDICINE
(2022)
Review
Immunology
Katherine A. Young, Hakim A. Ali, Kristi J. Beermann, John M. Reynolds, Laurie D. Snyder
Summary: Long term outcomes in lung transplant are limited by chronic lung allograft dysfunction (CLAD) development, with antibody-mediated rejection (AMR) recognized as a risk factor. High levels of HLA antibodies in lung transplant candidates may predispose them to AMR, CLAD, and higher mortality after transplant. The management of sensitized patients in lung transplant is crucial in improving outcomes.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Medicine, General & Internal
Je Seop Lee, Yong Sung Cha, Jihye Lim
Summary: There is currently no consensus on the number of hyperbaric oxygen therapy (HBO2) sessions within 24 hours of hospital admission for acute carbon monoxide (CO) poisoning. This study found that the number of HBO2 sessions implemented within 24 hours did not significantly affect neurocognitive outcomes in patients with CO poisoning.
FRONTIERS IN MEDICINE
(2023)
Review
Orthopedics
Motasem Salameh, Isam S. Moghamis, Osama Kokash, Ghalib O. Ahmed
Summary: This study reports a case series of pre-collapse avascular necrosis of the femoral head treated with hyperbaric oxygen, showing satisfactory clinical outcomes with significantly improved pain scores and low complications rate.
INTERNATIONAL ORTHOPAEDICS
(2021)
Article
Critical Care Medicine
Yoonsuk Lee, Yong Sung Cha, Sung Hwa Kim, Hyun Kim
Summary: Early initiation of HBO2 treatment within 6 hours post carbon monoxide exposure resulted in better neurocognitive outcomes at 6 months compared to treatment initiated within 6-24 hours. Increasing treatment delay interval was associated with worse prognosis.
CRITICAL CARE MEDICINE
(2021)
Article
Clinical Neurology
Joseph C. C. Maroon
Summary: This case study demonstrates the positive effects of HBO2 therapy on cognition, memory, cerebral perfusion, and physical function, as well as its role in regulating telomere length and inflammatory proteins.
FRONTIERS IN NEUROLOGY
(2022)
Review
Biochemistry & Molecular Biology
Julie Vinkel, Bjoern Arenkiel, Ole Hyldegaard
Summary: The perception of sepsis has changed, recognizing it as an imbalance in host cellular functions triggered by invading pathogens. Hyperbaric oxygen (HBO2) treatment has shown improvement in survival for patients with necrotizing soft tissue infections and sepsis models, possibly by affecting oxidative phosphorylation and cellular processes. This article argues for the protective effects of HBO2 treatment on tissue damage and the upregulation of anti-inflammatory measures in sepsis.
Article
Environmental Sciences
Pathan Mohsin Khan, Anna Lombardo, Emilio Benfenati, Kunal Roy
Summary: This study proposed QSPR models for predicting the hydrolysis half-life of organic chemicals under different pH and temperature conditions. The models found that specific functional groups and atom pairs in the molecules can affect the hydrolysis half-life, with aliphatic ether and ether groups leading to shorter half-lives, while higher unsaturation and nitrogen content contribute to longer half-lives. Additionally, it was observed that branched and compact molecules have shorter half-lives compared to straight chain analogues.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Emergency Medicine
Nicolas Delvau, Andrea Penaloza, Veronique Franssen, Frederic Thys, Pierre-Marie Roy, Philippe Hantson
Summary: Cardiac arrest (CA) following CO poisoning leads to high mortality and remains challenging to treat. We report a case of asystole in an CO-poisoned patient which failed to resuscitate after 101 minutes of CPR. Calculation of COHbt(1/2) using a single compartmental model suggested that prolonging CPR time may be beneficial for successful return of spontaneous circulation (ROSC).
INTERNATIONAL JOURNAL OF EMERGENCY MEDICINE
(2023)
Article
Dermatology
Richard Simman, Aurel Mihani, Jill Michalak, Marvin Heyboer
Summary: This case series evaluates the use of hyperbaric oxygen therapy (HBOT) in diverse clinical scenarios where limited information is available. The results show that all patients benefited from HBOT and experienced clinical improvement without adverse events. Healthcare providers may encounter unique situations when considering HBOT administration and may need to consult with experts or device manufacturers for optimal patient care.
WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
(2022)
Article
Neurosciences
Jiameng Wang, Long Xu, Qianqian Ge, Lianbi Xue, Yaling Liu, Cong Wang, Yue Wu, Yun Liu, Lichao Chen, Yutong Zhuang, Xiaoli Geng, Xueling Chen, Bo Wang, Qiuhong Yu, Jianghong He, Xudong Zhao
Summary: In this study, real-time EEG recordings were obtained from patients with disorders of consciousness (DOC) during hyperbaric oxygen (HBO) therapy. The results showed an increase in the duration of microstate C after 20 min of HBO therapy. Additionally, in patients with a higher CRS-R score, the transition probabilities between microstate A and microstate C significantly increased during HBO treatment.
FRONTIERS IN NEUROSCIENCE
(2023)
