Elevated expression of protein arginine methyltransferase 5 predicts the poor prognosis of breast cancer

Flavonoids of Rosa roxburghii Tratt exhibit radioprotection and anti-apoptosis properties via the Bcl-2(Ca2+)/Caspase-3/PARP-1 pathway

(2016) Ping Xu et al.   APOPTOSIS

PtdIns(3,4,5)P3-dependent Rac Exchanger 1 (PREX1) Rac-Guanine Nucleotide Exchange Factor (GEF) Activity Promotes Breast Cancer Cell Proliferation and Tumor Growth via Activation of Extracellular Signal-regulated Kinase 1/2 (ERK1/2) Signaling

(2016) Heng-Jia Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A TGFβ-PRMT5-MEP50 axis regulates cancer cell invasion through histone H3 and H4 arginine methylation coupled transcriptional activation and repression

(2016) H Chen et al.   ONCOGENE

ART3 regulates triple-negative breast cancer cell function via activation of Akt and ERK pathways

(2016) Ling Tan et al.   Oncotarget

Coronin 2A (CRN5) expression is associated with colorectal adenoma-adenocarcinoma sequence and oncogenic signalling

(2015) Raphael H. Rastetter et al.   BMC CANCER

NF-κB: Regulation by Methylation

(2015) Tao Lu et al.   CANCER RESEARCH

The PRMT5 arginine methyltransferase: many roles in development, cancer and beyond

(2015) Nicole Stopa et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Targeting protein arginine methyltransferase 5 inhibits human hepatocellular carcinoma growth via the downregulation of beta-catenin

(2015) Baolai Zhang et al.   Journal of Translational Medicine

Proliferative role of TRAF4 in breast cancer by upregulating PRMT5 nuclear expression

(2015) Fan Yang et al.   TUMOR BIOLOGY

Myc and Omomyc functionally associate with the Protein Arginine Methyltransferase 5 (PRMT5) in glioblastoma cells

(2015) Maria Patrizia Mongiardi et al.   Scientific Reports

Correction: HP1β Is a Biomarker for Breast Cancer Prognosis and PARP Inhibitor Therapy

(2015) Young-Ho Lee et al.   PLoS One

Genetic Validation of the Protein Arginine Methyltransferase PRMT5 as a Candidate Therapeutic Target in Glioblastoma

(2014) Fengting Yan et al.   CANCER RESEARCH

Breast Cancer in Adolescent and Young Adult Women

(2014) Hanan Gewefel et al.   Clinical Breast Cancer

Breast cancer in China

(2014) Lei Fan et al.   LANCET ONCOLOGY

Identification of a Novel Compound That Suppresses Breast Cancer Invasiveness by Inhibiting Transforming Growth Factor-β Signaling via Estrogen Receptor α

(2014) Natsuka Goto et al.   Journal of Cancer

Overexpression of PRMT5 Promotes Tumor Cell Growth and Is Associated with Poor Disease Prognosis in Epithelial Ovarian Cancer

(2013) Xiangxiang Bao et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein–RNA interaction networks from large-scale CLIP-Seq data

(2013) Jun-Hao Li et al.   NUCLEIC ACIDS RESEARCH

PRMT5 Is Upregulated in Malignant and Metastatic Melanoma and Regulates Expression of MITF and p27Kip1

(2013) Courtney Nicholas et al.   PLoS One

Protein arginine methyltransferase 5 is a potential oncoprotein that upregulates G1 cyclins/cyclin-dependent kinases and the phosphoinositide 3-kinase/AKT signaling cascade

(2012) Tong-You W. Wei et al.   CANCER SCIENCE

The RAS/RAF/MEK/ERK and the PI3K/AKT signalling pathways: role in cancer pathogenesis and implications for therapeutic approaches

(2012) Antonella De Luca et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Protein Arginine Methyltransferase 5 Accelerates Tumor Growth by Arginine Methylation of the Tumor Suppressor Programmed Cell Death 4

(2011) M. A. Powers et al.   CANCER RESEARCH

Versatility of PRMT5-induced methylation in growth control and development

(2011) Vrajesh Karkhanis et al.   TRENDS IN BIOCHEMICAL SCIENCES

GATExplorer: Genomic and Transcriptomic Explorer; mapping expression probes to gene loci, transcripts, exons and ncRNAs

(2010) Alberto Risueño et al.   BMC BIOINFORMATICS

Targeting the RAF–MEK–ERK pathway in cancer therapy

(2009) Clara Montagut et al.   CANCER LETTERS

Protein Arginine Methylation in Mammals: Who, What, and Why

(2009) Mark T. Bedford et al.   MOLECULAR CELL