期刊
TRENDS IN BIOTECHNOLOGY
卷 35, 期 11, 页码 1049-1061出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tibtech.2017.08.008
关键词
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资金
- National Institutes of Health [DP5OD019876]
- NIH/NHLBI [U01 HL125215]
- National Science Foundation [1512553]
- Div Of Chem, Bioeng, Env, & Transp Sys
- Directorate For Engineering [1512553] Funding Source: National Science Foundation
Noninvasive engineering models are now being used for diagnosing and planning the treatment of cardiovascular disease. Techniques in computational modeling and additive manufacturing have matured concurrently, and results from simulations can inform and enable the design and optimization of therapeutic devices and treatment strategies. The emerging synergy between large-scale simulations and 3D printing is having a two-fold benefit: first, 3D printing can be used to validate the complex simulations, and second, the flow models can be used to improve treatment planning for cardiovascular disease. In this review, we summarize and discuss recent methods and findings for lever-aging advances in both additive manufacturing and patient-specific computational modeling, with an emphasis on new directions in these fields and remaining open questions.
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