Editor’s Highlight: Base Excision Repair Variants and Pesticide Exposure Increase Parkinson’s Disease Risk

DNA repair pathways underlie a common genetic mechanism modulating onset in polyglutamine diseases

(2016) Conceição Bettencourt et al.   ANNALS OF NEUROLOGY

Genome-wide gene-environment interaction analysis of pesticide exposure and risk of Parkinson's disease

(2016) Joanna M. Biernacka et al.   PARKINSONISM & RELATED DISORDERS

Identification of Genetic Factors that Modify Clinical Onset of Huntington’s Disease

(2015) Jong-Min Lee et al.   CELL

Mitochondrial dysfunction and mitophagy in Parkinson's: from familial to sporadic disease

(2015) Brent J. Ryan et al.   TRENDS IN BIOCHEMICAL SCIENCES

Progress in unraveling the genetic etiology of Parkinson disease in a genomic era

(2015) Aline Verstraeten et al.   TRENDS IN GENETICS

ERCC6L2 Mutations Link a Distinct Bone-Marrow-Failure Syndrome to DNA Repair and Mitochondrial Function

(2014) Hemanth Tummala et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Prediction of paraquat exposure and toxicity in clinically ill poisoned patients: a model based approach

(2014) Klintean Wunnapuk et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease

(2014) Mike A Nalls et al.   NATURE GENETICS

Mitochondrial DNA damage: Molecular marker of vulnerable nigral neurons in Parkinson's disease

(2014) Laurie H. Sanders et al.   NEUROBIOLOGY OF DISEASE

Exposure to Mitochondrial Genotoxins and Dopaminergic Neurodegeneration in Caenorhabditis elegans

(2014) Claudia P. González-Hunt et al.   PLoS One

Mitochondrial DNA Damage as a Peripheral Biomarker for Mitochondrial Toxin Exposure in Rats

(2014) Laurie H. Sanders et al.   TOXICOLOGICAL SCIENCES

ACUTE EXPOSURE OFDrosophila melanogasterTO PARAQUAT CAUSES OXIDATIVE STRESS AND MITOCHONDRIAL DYSFUNCTION

(2013) Ravikumar Hosamani et al.   ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY

Oxidative damage to macromolecules in human Parkinson disease and the rotenone model

(2013) Laurie H. Sanders et al.   FREE RADICAL BIOLOGY AND MEDICINE

The current and projected economic burden of Parkinson's disease in the United States

(2013) Stacey L. Kowal et al.   MOVEMENT DISORDERS

LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: Reversal by gene correction

(2013) Laurie H. Sanders et al.   NEUROBIOLOGY OF DISEASE

Paraquat-Induced Ultrastructural Changes and DNA Damage in the Nervous System Is Mediated via Oxidative-Stress-Induced Cytotoxicity in Drosophila melanogaster

(2013) Syed Hassan Mehdi et al.   TOXICOLOGICAL SCIENCES

DNA Repair Genes in Parkinson's Disease

(2012) Mehmet Gencer et al.   Genetic Testing and Molecular Biomarkers

Impact of DNA polymorphisms in key DNA base excision repair proteins on cancer risk

(2012) B Karahalil et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Pesticide exposure and Parkinson's disease: Epidemiological evidence of association

(2012) Carmen Freire et al.   NEUROTOXICOLOGY

Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease

(2012) A. G. Fitzmaurice et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prostate Cancer and Ambient Pesticide Exposure in Agriculturally Intensive Areas in California

(2011) M. Cockburn et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Toxin Models of Mitochondrial Dysfunction in Parkinson's Disease

(2011) Terina N. Martinez et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial DNA toxicity compromises mitochondrial dynamics and induces hippocampal antioxidant defenses

(2011) Knut H. Lauritzen et al.   DNA REPAIR

Rotenone, Paraquat, and Parkinson’s Disease

(2011) Caroline M. Tanner et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Parkinson’s disease risk from ambient exposure to pesticides

(2011) Anthony Wang et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Paraquat induces behavioral changes and cortical and striatal mitochondrial dysfunction

(2011) A. Czerniczyniec et al.   FREE RADICAL BIOLOGY AND MEDICINE

Heritability of Parkinson disease in Swedish twins: a longitudinal study

(2011) Karin Wirdefeldt et al.   NEUROBIOLOGY OF AGING

Gene–environment interactions: Key to unraveling the mystery of Parkinson's disease

(2011) Hui-Ming Gao et al.   PROGRESS IN NEUROBIOLOGY

DNA repair deficiency in neurodegeneration

(2011) Dennis Kjølhede Jeppesen et al.   PROGRESS IN NEUROBIOLOGY

Increased Reactive Oxygen Species Production in the Brain After Repeated Low-Dose Pesticide Paraquat Exposure in Rats. A Comparison with Peripheral Tissues

(2010) Katarzyna Kuter et al.   NEUROCHEMICAL RESEARCH

Gene–environment interactions in Parkinson's disease and other forms of parkinsonism

(2010) Jeffery M. Vance et al.   NEUROTOXICOLOGY

Parkinson's Disease and Residential Exposure to Maneb and Paraquat From Agricultural Applications in the Central Valley of California

(2009) S. Costello et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Dopamine Transporter Genetic Variants and Pesticides in Parkinson’s Disease

(2009) Beate R. Ritz et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Pesticide exposure and risk of Parkinson's disease: A family-based case-control study

(2008) Dana B Hancock et al.   BMC Neurology

Meeting Report: Consensus Statement—Parkinson’s Disease and the Environment: Collaborative on Health and the Environment and Parkinson’s Action Network (CHE PAN) Conference 26–28 June 2007

(2008) Jeff Bronstein et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Pesticide/Environmental Exposures and Parkinson's Disease in East Texas

(2008) Amanpreet S. Dhillon et al.   Journal of Agromedicine