Magnetic Resonance and Ultrastructural Characterization of PEGylation-associated Vacuolation in Nonclinical Models

Quantitative Detection of PEGylated Biomacromolecules in Biological Fluids by NMR

(2016) Rohan D. A. Alvares et al.   ANALYTICAL CHEMISTRY

PEGylation of Biopharmaceuticals: A Review of Chemistry and Nonclinical Safety Information of Approved Drugs

(2016) Peter L. Turecek et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Direct quantitative13C-filtered1H magnetic resonance imaging of PEGylated biomacromolecules in vivo

(2016) Rohan D. A. Alvares et al.   MAGNETIC RESONANCE IN MEDICINE

Evaluation of Nonacog Beta Pegol Long-term Safety in the Immune-deficient Rowett Nude Rat (Crl:NIH-Foxn1rnu)

(2016) Caroline E. Rasmussen et al.   TOXICOLOGIC PATHOLOGY

Proton magnetic resonance spectroscopy in oncology: the fingerprints of cancer?

(2015) Roberto García Figueiras et al.   Diagnostic and Interventional Radiology

PEGylated Biopharmaceuticals

(2015) Inge A. Ivens et al.   TOXICOLOGIC PATHOLOGY

Proton magnetic resonance spectroscopy in oncology: the fingerprints of cancer?

(2015) Roberto García Figueiras et al.   Diagnostic and Interventional Radiology

Pharmacokinetics, metabolism and distribution of PEGs and PEGylated proteins: quo vadis?

(2014) Andreas Baumann et al.   DRUG DISCOVERY TODAY

High Molecular Weight Polyethylene Glycol Cellular Distribution and PEG-associated Cytoplasmic Vacuolation Is Molecular Weight Dependent and Does Not Require Conjugation to Proteins

(2013) Daniel G. Rudmann et al.   TOXICOLOGIC PATHOLOGY

Determination of 40 kDa polyethylene glycol (PEG) excretion after subcutaneous administration of certolizumab pegol to rats

(2012) T Parton et al.   INFLAMMATORY BOWEL DISEASES

The PEG Moiety of Certolizumab Pegol is Rapidly Cleared From the Blood of Humans by the Kidneys Once it is Cleaved From the Fabʼ

(2012) T Parton et al.   INFLAMMATORY BOWEL DISEASES

Evidence for Metabolic Cleavage of a PEGylated Protein in Vivo Using Multiple Analytical Methodologies

(2012) Victoria L. Elliott et al.   MOLECULAR PHARMACEUTICS

Physiological Effect of Polyethylene Glycol Conjugation on Stroma-Free Bovine Hemoglobin in the Conscious Dog After Partial Exchange Transfusion

(2010) Charles D. Conover et al.   ARTIFICIAL ORGANS