期刊
TETRAHEDRON
卷 73, 期 19, 页码 2780-2785出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2017.03.077
关键词
Indirubin; Synthesis; Isatin; KBH4; Reductive coupling
资金
- Natural Science Foundation of Shaanxi Province, China [2014JM4095]
- Xi'an City Science and Technology Project [CXY1511(6)]
- Shaanxi Province education department key laboratory project [16JS110]
- NSFC Enhanced Base Construction projects [J1210063]
- Program for Changjiang Scholars and Innovative Research Team in University [IRT-15R55]
One step synthesis of the natural product indirubin by reductive coupling of isatin with KBH4 is described and a possible mechanism for the reaction is proposed. Eleven indirubin derivatives were obtained easily from the corresponding substituted isatin. (C) 2017 Elsevier Ltd. All rights reserved.
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