期刊
TALANTA
卷 175, 期 -, 页码 256-263出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.talanta.2017.07.038
关键词
DESs; Homopolymerization and Copolymerization; Surface radical chain-transfer reaction; Stationary phase; Hydrophilic interaction chromatography
资金
- NSFC [21475142, 21465023, 21675164]
- funds for Distinguished Young Scientists of Gansu [1506RJDA281]
- Hundred Talents Program
- Chinese Academy of Sciences
In this paper, deep eutectic solvents (DESs) were firstly used as new and green solvents for the preparation of polymer-grafted silica stationary phases. 1-Vinylimidazole and acrylic acid were homopolymerized and copolymerized on silica via surface radical chain-transfer reaction in the DESs. Three stationary phases including poly(1-vinylimidazole)-, poly(acrylic acid)-, poly(1-vinylimidazole-co-acrylic acid)-grafted silica were obtained and characterized by elemental analysis and Fourier transform infrared spectroscopy. Their hydrophilic interaction chromatographic properties were investigated for separation of nucleosides, nucleobases, saccharides and amino acids. The retention changes of nucleosides and nucleobases on these columns were investigated under different chromatographic conditions including acetonitrile content, salt concentration, pH of mobile phase and column temperature. The repeatability of these columns was also investigated. The results demonstrate that DESs can be used as new media for the synthesis of silica-based stationary phases by homopolymerization and copolymerization on the surface of porous silica particles.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据