Common and Distinctive Functions of the Hippo Effectors Taz and Yap in Skeletal Muscle Stem Cell Function

The Hippo effector TAZ (WWTR1) transforms myoblasts and TAZ abundance is associated with reduced survival in embryonal rhabdomyosarcoma

(2016) Abdalla Mohamed et al.   JOURNAL OF PATHOLOGY

Characterization of Hippo Pathway Components by Gene Inactivation

(2016) Steven W. Plouffe et al.   MOLECULAR CELL

2016 update of the PRIDE database and its related tools

(2016) Juan Antonio Vizcaíno et al.   NUCLEIC ACIDS RESEARCH

Wnt signaling in bone and muscle

(2015) Michael A. Rudnicki et al.   BONE

Alternative Wnt Signaling Activates YAP/TAZ

(2015) Hyun Woo Park et al.   CELL

Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer

(2015) Fa-Xing Yu et al.   CELL

Aerobic glycolysis tunes YAP/TAZ transcriptional activity

(2015) E. Enzo et al.   EMBO JOURNAL

Yes-Associated Protein is up-regulated by mechanical overload and is sufficient to induce skeletal muscle hypertrophy

(2015) Craig A. Goodman et al.   FEBS LETTERS

YAP Drives Growth by Controlling Transcriptional Pause Release from Dynamic Enhancers

(2015) Giorgio G. Galli et al.   MOLECULAR CELL

Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway

(2015) Jung-Soon Mo et al.   NATURE CELL BIOLOGY

Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth

(2015) Francesca Zanconato et al.   NATURE CELL BIOLOGY

AMPK modulates Hippo pathway activity to regulate energy homeostasis

(2015) Wenqi Wang et al.   NATURE CELL BIOLOGY

YAP and TAZ: a nexus for Hippo signaling and beyond

(2015) Carsten Gram Hansen et al.   TRENDS IN CELL BIOLOGY

The Hippo pathway effector YAP is a critical regulator of skeletal muscle fibre size

(2015) K. I. Watt et al.   Nature Communications

Actin remodelling factors control ciliogenesis by regulating YAP/TAZ activity and vesicle trafficking

(2015) Jongshin Kim et al.   Nature Communications

Transcriptional Co-repressor Function of the Hippo Pathway Transducers YAP and TAZ

(2015) Minchul Kim et al.   Cell Reports

Selenoprotein W enhances skeletal muscle differentiation by inhibiting TAZ binding to 14-3-3 protein

(2014) Yeong Ha Jeon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Novel TAZ modulators enhance myogenic differentiation and muscle regeneration

(2014) Gun Hwa Park et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Hippo Transducer YAP1 Transforms Activated Satellite Cells and Is a Potent Effector of Embryonal Rhabdomyosarcoma Formation

(2014) Annie M. Tremblay et al.   CANCER CELL

YAP/TAZ Incorporation in the β-Catenin Destruction Complex Orchestrates the Wnt Response

(2014) Luca Azzolin et al.   CELL

Myomaker is essential for muscle regeneration

(2014) Douglas P. Millay et al.   GENES & DEVELOPMENT

Wnt7a stimulates myogenic stem cell motility and engraftment resulting in improved muscle strength

(2014) C. Florian Bentzinger et al.   JOURNAL OF CELL BIOLOGY

Dual role of YAP and TAZ in renewal of the intestinal epithelium

(2014) Masamichi Imajo et al.   NATURE CELL BIOLOGY

The Hippo signal transduction network in skeletal and cardiac muscle

(2014) H. Wackerhage et al.   Science Signaling

Energy Stress Regulates Hippo-YAP Signaling Involving AMPK-Mediated Regulation of Angiomotin-like 1 Protein

(2014) Michael DeRan et al.   Cell Reports

Cellular Mechanotransduction Relies on Tension-Induced and Chaperone-Assisted Autophagy

(2013) Anna Ulbricht et al.   CURRENT BIOLOGY

ErbB3 binding protein-1 (Ebp1) controls proliferation and myogenic differentiation of muscle stem cells

(2013) Nicolas Figeac et al.   DEVELOPMENTAL BIOLOGY

YAP and TAZ Regulate Skin Wound Healing

(2013) Min-Jung Lee et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Defining the Protein–Protein Interaction Network of the Human Hippo Pathway

(2013) Wenqi Wang et al.   MOLECULAR & CELLULAR PROTEOMICS

Constitutive Expression of Yes-Associated Protein (Yap) in Adult Skeletal Muscle Fibres Induces Muscle Atrophy and Myopathy

(2013) Robert N. Judson et al.   PLoS One

Six1 Regulates MyoD Expression in Adult Muscle Progenitor Cells

(2013) Yubing Liu et al.   PLoS One

Genomic insights into WNT/β-catenin signaling

(2013) Joseph Rosenbluh et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling

(2012) Fa-Xing Yu et al.   CELL

Organ Size Control by Hippo and TOR Pathways

(2012) Karen Tumaneng et al.   CURRENT BIOLOGY

Satellite cells are essential for skeletal muscle regeneration: the cell on the edge returns centre stage

(2012) F. Relaix et al.   DEVELOPMENT

Threonine-120 Phosphorylation Regulated by Phosphoinositide-3-Kinase/Akt and Mammalian Target of Rapamycin Pathway Signaling Limits the Antitumor Activity of Mammalian Sterile 20-Like Kinase 1

(2012) Filiz Kisaayak Collak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Hippo pathway member Yap plays a key role in influencing fate decisions in muscle satellite cells

(2012) R. N. Judson et al.   JOURNAL OF CELL SCIENCE

LKB1 tumor suppressor regulates AMP kinase/mTOR-independent cell growth and proliferation via the phosphorylation of Yap

(2012) H B Nguyen et al.   ONCOGENE

Hippo signaling in mammalian stem cells

(2012) Annie M. Tremblay et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Wnt signaling in myogenesis

(2012) Julia von Maltzahn et al.   TRENDS IN CELL BIOLOGY

Yap1 Acts Downstream of α-Catenin to Control Epidermal Proliferation

(2011) Karin Schlegelmilch et al.   CELL

Transcription factor TEAD4 regulates expression of Myogenin and the unfolded protein response genes during C2C12 cell differentiation

(2011) A Benhaddou et al.   CELL DEATH AND DIFFERENTIATION

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Regulation of Insulin-Like Growth Factor Signaling by Yap Governs Cardiomyocyte Proliferation and Embryonic Heart Size

(2011) M. Xin et al.   Science Signaling

Yap is a novel regulator of C2C12 myogenesis

(2010) Kevin I. Watt et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

BMP signalling permits population expansion by preventing premature myogenic differentiation in muscle satellite cells

(2010) Y Ono et al.   CELL DEATH AND DIFFERENTIATION

Chaperone-Assisted Selective Autophagy Is Essential for Muscle Maintenance

(2010) Verena Arndt et al.   CURRENT BIOLOGY

Regeneration of Mammalian Skeletal Muscle: Basic Mechanisms and Clinical Implications

(2010) Stefano Ciciliot et al.   CURRENT PHARMACEUTICAL DESIGN

The Crumbs Complex Couples Cell Density Sensing to Hippo-Dependent Control of the TGF-β-SMAD Pathway

(2010) Xaralabos Varelas et al.   DEVELOPMENTAL CELL

TAZ as a novel enhancer of MyoD-mediated myogenic differentiation

(2010) Hana Jeong et al.   FASEB JOURNAL

The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program

(2010) J. Cai et al.   GENES & DEVELOPMENT

Nuclear CDKs Drive Smad Transcriptional Activation and Turnover in BMP and TGF-β Pathways

(2009) Claudio Alarcón et al.   CELL

MOR23 Promotes Muscle Regeneration and Regulates Cell Adhesion and Migration

(2009) Christine A. Griffin et al.   DEVELOPMENTAL CELL

Phosphoinositide 3-Kinase/Akt Inhibits MST1-Mediated Pro-apoptotic Signaling through Phosphorylation of Threonine 120

(2009) Zengqiang Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An adult tissue-specific stem cell in its niche: A gene profiling analysis of in vivo quiescent and activated muscle satellite cells

(2009) Giorgia Pallafacchina et al.   Stem Cell Research

Syncoilin, an intermediate filament-like protein linked to the dystrophin associated protein complex in skeletal muscle

(2008) C. Moorwood   CELLULAR AND MOLECULAR LIFE SCIENCES

The CCN family of proteins: structure–function relationships

(2008) Kenneth P. Holbourn et al.   TRENDS IN BIOCHEMICAL SCIENCES