Stat3 is a candidate epigenetic biomarker of perinatal Bisphenol A exposure associated with murine hepatic tumors with implications for human health

IL-6, through p-STAT3 rather than p-STAT1, activates hepatocarcinogenesis and affects survival of hepatocellular carcinoma patients: a cohort study

(2015) Jung-Ta Kao et al.   BMC GASTROENTEROLOGY

A Review: Phytochemicals Targeting JAK/STAT Signaling and IDO Expression in Cancer

(2015) Niroshaathevi Arumuggam et al.   PHYTOTHERAPY RESEARCH

STAT3 acts through pre-existing nucleosome-depleted regions bound by FOS during an epigenetic switch linking inflammation to cancer

(2015) Joseph D Fleming et al.   Epigenetics & Chromatin

Reinforcement of STAT3 activity reprogrammes human embryonic stem cells to naive-like pluripotency

(2015) Hongwei Chen et al.   Nature Communications

Epigenetics of cancer stem cells: Pathways and therapeutics

(2014) Samriddhi Shukla et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Perinatal bisphenol A exposure promotes dose-dependent alterations of the mouse methylome

(2014) Jung H Kim et al.   BMC GENOMICS

Liver Damage, Inflammation, and Enhanced Tumorigenesis after Persistent mTORC1 Inhibition

(2014) Atsushi Umemura et al.   Cell Metabolism

STAT3 Mediates Regorafenib-Induced Apoptosis in Hepatocellular Carcinoma

(2014) W.-T. Tai et al.   CLINICAL CANCER RESEARCH

Bisphenol A Promotes Human Prostate Stem-Progenitor Cell Self-Renewal and Increases In Vivo Carcinogenesis in Human Prostate Epithelium

(2014) Gail S. Prins et al.   ENDOCRINOLOGY

Dose-Dependent Incidence of Hepatic Tumors in Adult Mice following Perinatal Exposure to Bisphenol A

(2014) Caren Weinhouse et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Methylation patterns of estrogen receptor α promoter correlate with estrogen receptor α expression and clinicopathological factors in hepatocellular carcinoma

(2014) Binghua Dai et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Evolutionary Origin and Methylation Status of Human Intronic CpG Islands that Are Not Present in Mouse

(2014) Katrin Rademacher et al.   Genome Biology and Evolution

Development of a Novel Azaspirane That Targets the Janus Kinase-Signal Transducer and Activator of Transcription (STAT) Pathway in Hepatocellular Carcinomain Vitroandin Vivo

(2014) Chakrabhavi Dhananjaya Mohan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic variants within the second intron of theKCNQ1gene affect CTCF binding and confer a risk of Beckwith–Wiedemann syndrome upon maternal transmission

(2014) Julie Demars et al.   JOURNAL OF MEDICAL GENETICS

Role of estrogen in hepatocellular carcinoma: is inflammation the key?

(2014) Liang Shi et al.   Journal of Translational Medicine

Prenatal Exposure to BPA Alters the Epigenome of the Rat Mammary Gland and Increases the Propensity to Neoplastic Development

(2014) Eugen Dhimolea et al.   PLoS One

Maternal nutrition at conception modulates DNA methylation of human metastable epialleles

(2014) Paula Dominguez-Salas et al.   Nature Communications

The Role of Dietary Histone Deacetylases (HDACs) Inhibitors in Health and Disease

(2014) Shalome Bassett et al.   Nutrients

Epigenetic biomarkers in laboratory diagnostics: emerging approaches and opportunities

(2013) Juan Sandoval et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Perinatal bisphenol A exposure promotes hyperactivity, lean body composition, and hormonal responses across the murine life course

(2013) Olivia S. Anderson et al.   FASEB JOURNAL

DNA-methylation effect on cotranscriptional splicing is dependent on GC architecture of the exon-intron structure

(2013) S. Gelfman et al.   GENOME RESEARCH

Dichlorodiphenyltrichloroethane technical mixture regulates cell cycle and apoptosis genes through the activation of CAR and ERα in mouse livers

(2013) Yuliya A. Kazantseva et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Methylation and liver cancer

(2013) Chiara Raggi et al.   Clinics and Research in Hepatology and Gastroenterology

Epigenetic responses following maternal dietary exposure to physiologically relevant levels of bisphenol A

(2012) Olivia S. Anderson et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Fetal Liver Bisphenol A Concentrations and Biotransformation Gene Expression Reveal Variable Exposure and Altered Capacity for Metabolism in Humans

(2012) Muna S. Nahar et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Association of cyclin D and estrogen receptor α36 with hepatocellular adenomas of female mice under chronic endoplasmic reticulum stress

(2012) Mo Yin Lau et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Transgenerational Actions of Environmental Compounds on Reproductive Disease and Identification of Epigenetic Biomarkers of Ancestral Exposures

(2012) Mohan Manikkam et al.   PLoS One

DNA Methylation of Intronic Enhancers Directs Tissue-Specific Expression of Steroidogenic Factor 1/Adrenal 4 Binding Protein (SF-1/Ad4BP)

(2011) Erling A. Hoivik et al.   ENDOCRINOLOGY

An expression microarray approach for the identification of metastable epialleles in the mouse genome

(2011) Caren Weinhouse et al.   Epigenetics

Gender-specific methylation differences in relation to prenatal exposure to cigarette smoke

(2011) Susan K. Murphy et al.   GENE

DNA Methylation of the First Exon Is Tightly Linked to Transcriptional Silencing

(2011) Fabienne Brenet et al.   PLoS One

Perinatal Exposure to Oestradiol and Bisphenol A Alters the Prostate Epigenome and Increases Susceptibility to Carcinogenesis

(2010) Gail S. Prins et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Subtype Classification of Hepatocellular Adenoma

(2010) Paulette Bioulac-Sage et al.   DIGESTIVE SURGERY

Conserved role of intragenic DNA methylation in regulating alternative promoters

(2010) Alika K. Maunakea et al.   NATURE

IL-6/gp130/STAT3 signaling axis in cancer and the presence of in-frame gp130 somatic deletions in inflammatory hepatocellular tumors

(2009) Rafael Rosell et al.   Future Oncology

Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells

(2009) Madeleine P Ball et al.   NATURE BIOTECHNOLOGY

A human B cell methylome at 100−base pair resolution

(2009) Tibor A. Rauch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-18a Prevents Estrogen Receptor-α Expression, Promoting Proliferation of Hepatocellular Carcinoma Cells

(2008) Wan–Hsin Liu et al.   GASTROENTEROLOGY

Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours

(2008) Sandra Rebouissou et al.   NATURE

Shotgun bisulphite sequencing of the Arabidopsis genome reveals DNA methylation patterning

(2008) Shawn J. Cokus et al.   NATURE