High-throughput concentration-response analysis for omics datasets

Linking toxicity and adaptive responses across the transcriptome, proteome, and phenotype ofChlamydomonas reinhardtiiexposed to silver

(2014) Smitha Pillai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Benchmarking Organic Micropollutants in Wastewater, Recycled Water and Drinking Water with In Vitro Bioassays

(2013) Beate I. Escher et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Simplifying complexity: Mixture toxicity assessment in the last 20 years

(2013) Rolf Altenburger et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Incorporating New Technologies Into Toxicity Testing and Risk Assessment: Moving From 21st Century Vision to a Data-Driven Framework

(2013) Russell S. Thomas et al.   TOXICOLOGICAL SCIENCES

Transcriptomic analysis in the developing zebrafish embryo after compound exposure: Individual gene expression and pathway regulation

(2013) Sanne A.B. Hermsen et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Spatial and temporal variation in metabolic fingerprints of field-growing Myriophyllum spicatum

(2012) J. Riedl et al.   AQUATIC BOTANY

Mixture Toxicity Revisited from a Toxicogenomic Perspective

(2012) Rolf Altenburger et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Integrating pathway-based transcriptomic data into quantitative chemical risk assessment: A five chemical case study

(2012) Russell S. Thomas et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

Modeling Effective Dosages in Hormetic Dose-Response Studies

(2012) Regina G. Belz et al.   PLoS One

Concentration-Response Analysis of Differential Gene Expression in the Zebrafish Embryotoxicity Test Following Flusilazole Exposure

(2012) Sanne A. B. Hermsen et al.   TOXICOLOGICAL SCIENCES

Concentration–response concept in ecotoxicoproteomics: Effects of different phenanthrene concentrations to the zebrafish (Danio rerio) embryo proteome

(2011) Ulrike Gündel et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

A New Transcriptional Effect Level Index (TELI) for Toxicogenomics-based Toxicity Assessment

(2011) Na Gou et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Toward a unified approach to dose-response modeling in ecotoxicology

(2010) Christian Ritz   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Decision tree supported substructure prediction of metabolites from GC-MS profiles

(2010) Jan Hummel et al.   Metabolomics

Automated Dose-Response Analysis and Comparative Toxicogenomic Evaluation of the Hepatic Effects Elicited by TCDD, TCDF, and PCB126 in C57BL/6 Mice

(2010) Anna K. Kopec et al.   TOXICOLOGICAL SCIENCES

Anchoring metabolic changes to phenotypic effects in the chlorophyte Scenedesmus vacuolatus under chemical exposure

(2009) Frédéric Sans-Piché et al.   MARINE ENVIRONMENTAL RESEARCH

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Proteins in ecotoxicology - How, why and why not?

(2009) Marco F. L. Lemos et al.   PROTEOMICS

Simultaneous Inference in General Parametric Models

(2008) Torsten Hothorn et al.   BIOMETRICAL JOURNAL

A metabolomics approach to assessing phytotoxic effects on the green alga Scenedesmus vacuolatus

(2008) Christina Kluender et al.   Metabolomics

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH

Hormesis in mixtures — Can it be predicted?

(2008) Regina G. Belz et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Automated Quantitative Dose-Response Modeling and Point of Departure Determination for Large Toxicogenomic and High-Throughput Screening Data Sets

(2008) Lyle D. Burgoon et al.   TOXICOLOGICAL SCIENCES

Is the integration of hormesis and essentiality into ecotoxicology now opening Pandora's Box?

(2007) Ben J. Kefford et al.   ENVIRONMENTAL POLLUTION