Article
Chemistry, Analytical
Yuhua Liu, Liju Tan, Kunpeng Wang, Jiangtao Wang
Summary: A magnetic molecularly imprinted probe was synthesized and successfully applied for the detection of malachite green in seawater, achieving satisfactory results.
Article
Biochemistry & Molecular Biology
Xiaoxiao Chen, Yang Liu, Pu Li, Yichen Xing, Chaobiao Huang
Summary: A method for the trace detection of chloramphenicol (CAP) was established using a dual recognition system with a fluorescence quenching of quantum dots (QDs) and specific recognition of molecularly imprinted polymer (MIP). The MIP@SiO2@QDs showed good detection selectivity for CAP and was successfully applied to quantify CAP in lake water with promising potential for on-site detection in environmental waters.
Review
Chemistry, Analytical
Rustem Kecili, Chaudhery Ghazanfar Hussain, Chaudhery Mustansar Hussain
Summary: This paper summarises the recent developments in the fabrication of MIPs-coated green CDs as powerful sensing platforms for the determination of various compounds in complex samples (i.e. biological, food and environmental matrices).
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Article
Materials Science, Biomaterials
Jixiang Wang, Xiaolei Li, Rong Zhang, Bingjie Fu, Mingcan Chen, Mengxue Ye, Wanyu Liu, Jingjing Xu, Guoqing Pan, Hongbo Zhang
Summary: In this study, a fluorescent sensor based on molecularly imprinted magnetic hahoysite nanotubes (MHNTs@FMIP5) was designed and synthesized for the effective detection and purification of OTC in actual environmental samples. The sensor exhibited low detection limit, excellent specificity, and potential applications.
JOURNAL OF MATERIALS CHEMISTRY B
(2022)
Review
Polymer Science
Roberta Del Sole, Giuseppe Mele, Ermelinda Bloise, Lucia Mergola
Summary: Molecular Imprinting Polymer (MIP) technology, focusing on the design of artificial receptors with predetermined selectivity, has gained attention in recent years, especially in the context of green synthesis. Research efforts have been directed towards utilizing biomass waste for preparing MIPs, showing promise as a sustainable alternative source for high-value carbon-based materials.
Article
Chemistry, Analytical
Jiadi Sun, Chen Chen, Yinzhi Zhang, Xiulan Sun
Summary: The novel fluorescent molecularly imprinted polymer SiO2@CdTe QDs@MIP proposed in this paper shows great potential for efficient PQ detection and adsorption. The synthesized MIP exhibits high detection sensitivity and adsorption capacity, offering an effective method for PQ detection and purification.
Article
Chemistry, Analytical
Tianhao Li, Zhiwei Deng, Jiaqi Bu, Hui Liu, Yanjing Yang, Shian Zhong
Summary: A test strip for selective detection of ferritin was developed by integrating molecular imprinting technology and multicolor fluorescence elements. The test strip showed high specificity for ferritin and allowed for rapid and visual detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Applied
Jingyao Qiu, Lihua Na, Yuanming Li, Wenfeng Bai, Jianpo Zhang, Li Jin
Summary: A ratiometric fluorescence sensor was constructed using CdTe quantum dots and N,S-GQDs for the visual detection and quantitative analysis of malachite green. The color of the sensor changed from red to blue under UV light, depending on the concentration of malachite green. The lowest detection limit was 0.4597 nmol/L.
Article
Food Science & Technology
Shujuan Chen, Wanlin Ouyang, Yiting Zhu, Jing Han, Yanan Zhang, Likou Zou, Juan Deng, Aiping Liu, Shuliang Liu, Yong Yang
Summary: An environmentally friendly nitrogen-sulfur-doped carbon quantum dots molecularly imprinted fluorescent probe (N,S-CDs@MIP) was developed for detecting thiamphenicol (TAP) in animal-derived foods. The probe showed fluorescence response to TAP in the range of 10.00 to 300.0 μg/L, with a detection limit of 6.20 μg/L. It was successfully applied to real milk, fish, and tap water with recoveries of 92.08-108.4%, which matched the results of high-performance liquid chromatography (HPLC) analysis (89.15%-110.7%). The developed probe is cost-effective and has a short detection time (30 min), providing a theoretical and practical basis for monitoring TAP residue levels.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Chemistry, Analytical
Li Liu, Maomin Peng, Ke Xu, Hong Xia, Xitian Peng, Lijun Peng, Jin Z. Zhang
Summary: Molecularly imprinted polymers with methylammonium lead halide perovskite quantum dots were prepared and used for the determination of benzo(a)pyrene. The interaction between MIP@MAPbBr(3) PQDs and BaP is a dynamic process, enhancing the PL intensity. The molecularly imprinted fluorescence assay shows good specificity and selectivity for BaP in complex mixtures.
Article
Chemistry, Analytical
Ping Li, Hao Fu, Zhenyu Bai, Xiaoyang Feng, Ji Qi, Xingliang Song, Xueping Hu, Lingxin Chen
Summary: An effective strategy is proposed to construct a highly sensitive ratiometric fluorescence sensing platform for microcystins (MCs) based on a dummy molecularly imprinted polymer using metformin as a template. The imprinted nanohybrids of carbon dots (CDs) combined with fluorescein isothiocyanate (FITC) are synthesized (CDs-FITC-SiO2@MIP), in which the CDs and FITC serve as assisted response signals and reference enhancement signals, respectively. This method has great potential for monitoring MCs in complex systems.
Review
Chemistry, Analytical
Myriam Diaz-Alvarez, Antonio Martin-Esteban
Summary: This paper reviews the development of optical sensors using a combination of quantum dots and molecularly imprinted polymers. These sensors overcome the limitations of traditional analytical methods and improve sensor selectivity and sensitivity.
Review
Chemistry, Analytical
Saeedeh Ansari, Saeed Masoum
Summary: This article mainly focuses on the design, sensing mechanisms, and properties of MIP/CDs-based fluorescent sensors in recent years, highlighting the importance and potential value of MIP/CDs in sensing systems.
Article
Polymer Science
Wenming Yang, Qunxiang Fang, Liming Zhang, Haiqin Yin, Changchun Wu, Wenwen Zhang, Weihong Huang, Xiaoni Ni
Summary: A novel molecular imprinted polymer based on KH-570 modified SiO2-coated CdTe quantum dots was developed as a fluorescence sensor for sensitive and selective detection of sulfadimidine (SM2). The sensors exhibited good structure, high sensitivity with a wide linear range, and were successfully applied in detecting SM2 in water samples with high recovery rates and low relative standard deviations, showing potential for real sample detection applications.
JOURNAL OF POLYMER RESEARCH
(2021)
Article
Chemistry, Applied
Yunyan Ren, Zhefeng Fan
Summary: In this study, nitrogen-doped carbon dot-based molecularly imprinted polymers (N-CDs@MIPs) were successfully prepared for the trace analysis of tobramycin in milk. The probe showed high sensitivity and selectivity compared to other techniques and can be an alternative method for the detection of tobramycin.
Article
Chemistry, Analytical
Qingyang Si, Yumeng Li, Ziling Huang, Chuanyi Liu, Xiaomei Chen, Jie Wei, Fuan Wang
Summary: In this study, a simple, efficient, and reliable dual-mode sensing system based on hemin-G-quadruplex (G4) DNAzyme was established to detect adenosine triphosphate (ATP) and assess fish freshness. The system enables highly sensitive and reliable analysis of target ATP, and the ATP level detected in perch samples was linearly correlated with microbial content. The proposed DNAzyme-based dual-mode strategy for freshness evaluation offers a promising and cost-effective method for food safety and quality monitoring.
ANALYTICA CHIMICA ACTA
(2023)
Article
Chemistry, Analytical
Rui Ge, Hanjie Dai, Shumin Zhang, Jie Wei, Tianhui Jiao, Qingmin Chen, Quansheng Chen, Xiaomei Chen
Summary: In this study, a photoelectrochemical (PEC) biosensor combined with recombinase polymerase amplification (RPA) technology (RPA-PEC) was proposed for rapid detection of multiple foodborne pathogens. The RPA was initiated on homemade three-dimensional screen-printed paper-based electrodes, forming a lab-on-paper platform. Using the DNA-PEC signaler, photocurrents were achieved after only 20 minutes of RPA, with superior detection performance compared to conventional agarose gel electrophoresis.
ANALYTICAL CHEMISTRY
(2023)
Correction
Chemistry, Applied
Xueqi Lin, Ning Li, Qiao Xiao, Yaping Guo, Jie Wei, Tianhui Jiao, Qingmin Chen, Quansheng Chen, Xiaomei Chen
Article
Chemistry, Analytical
Zisen Wu, Dongyan Chen, Haodi Liu, Anhui Lin, Quansheng Chen, Xiaomei Chen
Summary: A turn off-on fluorescent sensor based on Fe-MOF was developed for highly sensitive determination of TBHQ. The sensor showed good selectivity, reproducibility, and stability for TBHQ detection. The practicality of the method was demonstrated by the detection of TBHQ in soybean oil, providing consistent results with conventional high-performance liquid chromatography.
ANALYTICA CHIMICA ACTA
(2023)
Article
Chemistry, Applied
Yumeng Li, Qingyang Si, Chuanyi Liu, Ziling Huang, Qingmin Chen, Tianhui Jiao, Xiaomei Chen, Quansheng Chen, Jie Wei
Summary: Improper use of kanamycin can result in trace residues in animal-derived foods, posing a potential threat to public health. In this study, a nonenzymatic self-driven hybridization chain reaction (SHCR) amplifier was developed for kanamycin determination, with 5800-fold higher sensitivity than conventional HCR circuit. The self-sustainable SHCR aptasensor demonstrated highly sensitive and reliable analysis of kanamycin in buffer, milk, and honey samples, offering great potential for amplified detection of trace contaminants in liquid food matrices.
Article
Chemistry, Applied
Dongyan Chen, Zisen Wu, Yize Zhang, Dong Li, Jie Wei, Tianhui Jiao, Qingmin Chen, Munetaka Oyama, Quansheng Chen, Xiaomei Chen
Summary: This study developed a fluorescent platform based on a Tb-MOF for detecting propyl gallate (PG). The Tb-MOF exhibited multiple emissions and its fluorescence was weakened when PG was present. The sensor enabled rapid and selective determination of PG in soybean oil, providing a new route to monitor and reduce the overuse of PG.
Article
Food Science & Technology
Shang Wang, Silin Huang, Yuying Han, Jian Wu, Tianhui Jiao, Jie Wei, Xiaomei Chen, Qingmin Chen, Quansheng Chen
Summary: This study utilized the colorimetric sensing array (CSA) technique with two data collection blocks, imaging and visible near-infrared spectroscopy, to non-destructively predict the total volatile basic nitrogen (TVB-N) content in Fujian oysters. Three data fusion strategies coupled with variable selection approaches were applied to establish the partial least squares (PLS) model for prediction. The results demonstrated that the use of CSA has the potential for non-destructive monitoring of TVB-N content in Fujian oysters, with the high-level-VCPA strategy showing the best performance (Rp=0.9128) among the tested approaches.
Article
Agriculture, Multidisciplinary
Xin-Rong He, Yang Yang, Ye-Xin Chen, Shuai Kang, Fa-Jie Li, Dong-Xiao Li, Qing-Mei Liu, Gui-Xia Chen, Xiao-Mei Chen, Guang-Ming Liu
Summary: This study investigated the IgE epitope and structure-allergenicity relationship of Scy p 9. A hydrophobic bond was found to be important for maintaining the conformation of Scy p 9. Mutagenesis experiments revealed that key amino acid mutations reduced the IgE-binding capacity and surface hydrophobicity of the mutants. Ten linear epitopes were identified, with L-AA(187-205) showing the strongest IgE binding. IgE epitopes were mapped on the protruding surface of the Scy p 9 tertiary structure and were highly conserved among filamin genes.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Agriculture, Multidisciplinary
Jinjin Wang, Silun Li, Jie Wei, Tianhui Jiao, Qingmin Chen, Munetaka Oyama, Quansheng Chen, Xiaomei Chen
Summary: To prevent contamination of cereals by mycotoxins, a sensitive and rapid method for mycotoxin detection is essential. In this study, a screening-capture-integrated electrochemiluminescence (ECL) aptasensor based on mesoporous silica films (MSFs) was developed for the ultrasensitive and highly selective detection of deoxynivalenol (DON) in wheat. The sensor combines size screening and specific capture to achieve quantitative detection of DON, providing a new approach for early detection of wheat mildew.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Chemistry, Analytical
Zhi-Yong Guo, Chen Zhang, Lin-min Chen, Mei-huang Zeng, Qiu-hong Yao, Ting-Xiu Ye, He-zhou Luo, Xiao-mei Chen, Xi Chen
Summary: Shell-isolated colloid plasmonic nanomaterials-based nanoreactor is a versatile platform widely used in catalyst or SERS sensors. A competitive conjugative-mediated nanoreactor is introduced to determine glucose with SERS, which constructs glucose-conjugating nanoreactor using coordinated deposition colloidal gold nanoparticles with sodium nitroprusside framework (Au@SNF) and covalently bonded 4-mercaptopyridine (4-Mpy). The nanoreactor combines well-defined structure, conjugative-mediated mechanism, and internal standards method for improved signal indication and correction, enabling quantitative SERS detection of glucose in complex samples.
Article
Chemistry, Analytical
Xueqi Lin, Yuwen Fang, Quansheng Chen, Zhiyong Guo, Xi Chen, Xiaomei Chen
Summary: A portable fluorescent/colorimetric sensor based on G-quadruplex DNAzyme was constructed for rapid and dual-mode detection of ochratoxin A (OTA) in wheat. The sensor utilized OTA aptamers coupled with magnetic beads (MBs) to form a G-quadruplex DNAzyme structure that could catalyze an oxidation reaction and produce strong fluorescence. A magnet-controlled chip was designed to improve detection efficiency and sensitivity. A portable detection platform was built for on-site OTA detection.
Article
Chemistry, Analytical
Hanjie Dai, Shumin Zhang, Jie Wei, Tianhui Jiao, Qingmin Chen, Quansheng Chen, Xiaomei Chen
Summary: This study presents a self-powered photoelectrochemical (PEC) aptasensing platform for the detection of microcystin-LR (MC-LR). By integrating different types of semiconductor materials, the problem of inconspicuous photocurrent in PEC analysis is effectively solved. The constructed sensor exhibits high sensitivity, good anti-interference properties, and reproducibility.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Analytical
Xueqi Lin, Yuwen Fang, Jie Wei, Tianhui Jiao, Qingmin Chen, Quansheng Chen, Xiaomei Chen
Summary: In this study, a dual-mode sensor based on Gd2O3:Eu3+ nanoparticles was developed for the detection of aflatoxin B1 in grain. The Gd2O3:Eu3+ exhibited concentration-dependent magnetic relaxation switch and fluorescence responses, serving as a dual-mode signal probe. By combining immunologic recognition, magnetic separation, and the unique properties of Gd2O3:Eu3+, a dual-mode Sandwich immunoassay was constructed, enabling high sensitivity and strong anti-interference detection of aflatoxin B1.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Analytical
Hanjie Dai, Mingming Yin, Shumin Zhang, Jie Wei, Tianhui Jiao, Qingmin Chen, Quansheng Chen, Xi Chen, Munetaka Oyama, Xiaomei Chen
Summary: In this study, a novel paper-based photoelectrochemical sensor was developed for rapid and sensitive detection of Staphylococcus aureus. By utilizing specific modifications, the capture of S. aureus with high specificity was achieved, and signal enhancement was achieved using nanoflower probes. The sensor demonstrated rapid and ultrasensitive detection capabilities.
Article
Chemistry, Applied
Xueqi Lin, Rui Ge, Jie Wei, Tianhui Jiao, Qingmin Chen, Munetaka Oyama, Quansheng Chen, Xiaomei Chen
Summary: This study developed a magnetic-encoded fluorescent nanosphere-based immunosensor for simultaneous detection of multiple mycotoxins in wheat. The sensor showed high accuracy, selectivity, and sensitivity.
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)