Article
Chemistry, Analytical
Xinyu Bai, Wenkai Gao, Chaohui Zhou, Danyang Zhao, Yao Zhang, Nengqin Jia
Summary: A novel molecular imprint photoelectrochemical (PEC) sensor based on oriented single-crystalline TiO2 nanoarray (TNA) material was prepared for sensitive detection of diclofenac (DCF). The sensor exhibited good sensitivity and selectivity, with a wide detection range and low detection limit for DCF. It also showed good repeatability and stability.
Article
Chemistry, Physical
Teera Butburee, Yang Bai, Lianzhou Wang
Summary: Branched nanostructures, specifically branched titanium dioxide, show potential as photocatalysts for energy conversion applications. By using a one-pot hydrothermal synthesis method, researchers have successfully controlled the growth of these nanostructures from zero-dimensional to one-dimensional and two-dimensional structures, leading to improved photocatalytic performance in photoelectrochemical water splitting.
JOURNAL OF MATERIALS CHEMISTRY A
(2021)
Article
Materials Science, Ceramics
Lakshmana Reddy Nagappagari, Santosh S. Patil, Jaewon Lee, Eunoak Park, Yeon-Tae Yu, Kiyoung Lee
Summary: The study investigates the growth of well-aligned spaced TiO2 nanorod arrays on FTO substrate, which enhances the PEC performance. The calcination time ranging from 1 to 5 hours at 400 degrees Celsius significantly impacts the structure of the nanorods, resulting in spaced nanorods with improved transfer efficiency of internal charge carriers. The heterojunction formation with NiCo2S4 via the SILAR method improves PEC performance by reducing charge carrier recombination at the interface.
CERAMICS INTERNATIONAL
(2022)
Article
Chemistry, Analytical
Junhong Zhao, Jing Cheng, Yudong Sun, Jiang Liu, Wen Chen, Yi Xu, Jiao Yang, Yingchun Li
Summary: A novel photoelectrochemical sensor based on Z-scheme TiO2@Au@CdS and molecularly imprinted polymer (MIP) was developed for non-invasive detection of uric acid. The sensor showed desirable sensing performance with high sensitivity, selectivity, repeatability, and stability, and has potential for detecting other small molecules.
Article
Biophysics
Danyang Zhao, Yao Zhang, Shaowei Ji, Yao Lu, Xinyu Bai, Mengting Yin, Chusen Huang, Nengqin Jia
Summary: The proposed highly sensitive quenching molecular imprinting photoelectrochemical sensor demonstrates efficient detection of acrylamide with excellent specificity, sensitivity, and stability, making it suitable for monitoring potential risks in food samples.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Materials Science, Ceramics
S. Swathi, E. Sunil Babu, R. Yuvakkumar, G. Ravi, Arunachalam Chinnathambi, Sulaiman Ali Alharbi, Dhayalan Velauthapillai
Summary: Photoelectrochemical water splitting using semiconductor materials to generate hydrogen and oxygen is an important method. Synthesized materials can enhance bandgap by controlled size and morphology, improving PEC activity and photoconversion efficiency. Recently, ZnO nanostructures have attracted attention for their multifunctional properties and are considered outstanding for fabrication applications.
CERAMICS INTERNATIONAL
(2021)
Article
Chemistry, Analytical
Jiawen Wu, Panpan Ou, Yu Lin, Xuecai Tan, Fucun Wei, Yan Mi, Shaogang Liu, Kejing Huang
Summary: This study developed a highly efficient photoelectrochemical sensor for detecting chlorpyrifos in the environment by introducing oxygen vacancies and loading bismuth sulfide nanoparticles. The sensor showed high sensitivity and accuracy, making it suitable for detecting chlorpyrifos in vegetables.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Yun Cai, Fengyu Yuan, Fan Li, Huihui Kang, Daxiang Xue, Siping Huo, Fengjiao Yu, Jun Fang, Yang Yang
Summary: The Au/TiO2-based system with the right combination of electronic configuration, structural dynamics, and stability has attracted wide attention in PEC water splitting for hydrogen generation. In this study, Au nanoparticles were used to fabricate TiO2 nanowire arrays, resulting in significantly increased photocurrent density and improved PEC activity towards water oxidation when used as a photoanode. The dewetted Au nanoparticles played dual functions in regulating and passivating the TiO2 nanowires, leading to efficient charge carrier generation, transfer, and separation for boosted PEC water oxidation performance.
Article
Chemistry, Physical
Xin Yan, Ken Sakai, Hironobu Ozawa
Summary: Photoelectrochemical overall water splitting by semiconductor electrodes modified with functional molecules has attracted attention. Achieving overall water splitting using molecular-based photoanodes and Pt cathode is challenging due to the desorption of molecules. A pyridyl anchoring technique is demonstrated to improve the stability and efficiency of molecular-based photoanodes.
Article
Chemistry, Analytical
Rui Xu, Yu Du, Lei Liu, Dawei Fan, Liangguo Yan, Xuejing Liu, Huan Wang, Qin Wei, Huangxian Ju
Summary: A novel molecularly imprinted photoelectrochemical (PEC) sensor was designed for bisphenol A (BPA) analysis based on In2S3/Cd2+ sensitized flower-like AgBiS2, showing enhanced PEC response and wide detection range with low detection limit. The sensor utilized a bimetallic sulphide AgBiS2 with favorable surface morphology for fixing photoactive nanomaterials, and the combination of different sensitizers achieved satisfactory PEC basic response.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Multidisciplinary
Run Yuan, Bingdong Yan, Caiyan Lai, Xiaohong Wang, Yang Cao, Jinchun Tu, Yi Li, Qiang Wu
Summary: In this study, a visible light-driven PEC enzyme biosensor was proposed for the sensitive and rapid detection of glucose. The biosensor utilized CDs/branched TiO2 (B-TiO2) as the photoactive material and glucose oxidase (GOx) as the identification element. The biosensor showed good sensing performance with a detection range of 0 to 9.00 mM and a detection limit of 0.0430 mM for glucose under visible light.
Article
Engineering, Electrical & Electronic
Hoang Nhat Hieu, Nguyen Van Nghia, Nguyen Minh Vuong, Loan Le Thi Ngoc, Thanh Hai Phan
Summary: We reported a rational and simple approach to fabricate heterojunction CdS/CuO/ZnO branched nanowires as photoelectrodes for highly efficient water splitting. The optimized photoelectrode showed significantly enhanced photoconversion efficiency of 3.9% under solar simulation, which is much higher than other photoelectrodes.
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
(2022)
Article
Chemistry, Multidisciplinary
Jing Huang, Tao Chen, Mingyang Zhao, Ping Yi, Feifan Zhao, Bing He, Yang Wang, Yihuang Chen, Xueqin Liu, Zhen Li
Summary: In this study, a high energy electron beam was used to modify the surface structure of TiO2 nanorod arrays, leading to enhanced photoelectrochemical water splitting activity through the introduction of oxygen vacancies. The concentration of surface oxygen vacancies can be controlled by adjusting irradiation doses, which is key in influencing the photoelectrochemical performance. The photocurrent density is significantly increased after modification, without the need for typical doping or catalyst modification.
Article
Chemistry, Analytical
Delun Zheng, Jinbiao Xie, Shaoqin Zheng, Min Chen, Yaowen Chen, Wenhua Gao
Summary: Photoactive Co3O4@C/TiO2 composite with heterostructures was fabricated for efficient photoelectrochemical (PEC) detection. The honeycombed and thin-shelled Co3O4@C enhanced visible-light harvesting capacity, while the high porosity facilitated electrolyte infiltration and electronic transportation efficiency. The p-n-type heterojunction interface between Co3O4@C and TiO2 prevented recombination and enhanced migration of photo-induced charge carriers. The developed AChE/CS-GLD/Co3O4@C/TiO2/ITO sensing platform exhibited high sensitivity and specificity for chlorpyrifos detection.
MICROCHEMICAL JOURNAL
(2023)
Article
Physics, Applied
Gang Wang, Zhaowen Bai, Hongchang Wu, Xinmiao Zhang, Jiang Li, Mengjing Jin, Jinyuan Zhou, Erqing Xie, Xiaojun Pan
Summary: This work demonstrates a wire-shaped photoelectrochemical type ultraviolet photodetector based on a titanium dioxide nanotube array (TNAs) photoanode fabricated by electrochemical anodization. The detector exhibits high photocurrent density, high ON/OFF ratio, and fast response time, as well as visible-blind characteristics and excellent linear response under weak irradiation. These results are beneficial for the realization of omnidirectional and wearable optoelectronic devices.
APPLIED PHYSICS LETTERS
(2022)
Article
Nanoscience & Nanotechnology
Yaqi Liu, Fengyi Wang, Shuo Ge, Lu Zhang, Zuhao Zhang, Yunqing Liu, Yan Zhang, Shenguang Ge, Jinghua Yu
Summary: A strand displacement amplification (SDA)-assisted CRISPR/Cas12a electrochemiluminescence (ECL) biosensor was developed for ultrasensitive detection of Staphylococcus aureus (Sa)-16S rDNA. The biosensor utilized a porphyrinic Zr metal-organic framework (MOF) as a coreactant accelerator to enhance the ECL emission signal. The presence of Sa-16S rDNA triggered the SDA reaction, generating single-stranded DNA products (SP) that activated the CRISPR/Cas12a trans-cleavage and effectively extinguished the ECL signals. The ECL platform exhibited high sensitivity and specificity, making it suitable for clinical diagnosis.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Analytical
Qingxin Zhang, Manru Zhang, Zhiqiang Guo, Jingjing Li, Zhixue Zhu, Yu Wang, Su Liu, Jiadong Huang, Jinghua Yu
Summary: In this study, a low-background electrochemical biosensor based on a DNA tetrahedron-besieged primer and a DNAzyme-activated programmatic rolling circle amplification (RCA) was proposed for OTA detection in wine samples. The low-background detection was achieved by using the besieged primer and the target OTA-mediated DNAzyme activation initiated the programmatic RCA. The integration of the catalytic property of silver nanoclusters (AgNCs) with the electrochemical assay provided high sensitivity for OTA detection. This novel design showed great potential in food safety and environmental detection.
ANALYTICA CHIMICA ACTA
(2023)
Article
Chemistry, Physical
Shuai Yu, Xujie Gao, Shenguang Ge, Yuanchang Ma, Yaqi Han, Xingzhu Wang, Fumin Xue, Long Fu
Summary: The solubility of glimepiride in five binary solvent mixtures was measured using a gravimetric method. The solubility order in selected solvents was DMA + acetonitrile > DMA + methanol > DMA + ethanol > DMA + n-propanol approx. DMA + i-propanol. Solubility increased with temperature and DMA content. Four thermodynamic models were used to correlate the solubility data, with the NRTL and JAA models fitting the data the best. The solubility data in mixed solvents will be useful for the preparation and purification of this active pharmaceutical ingredient.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Chemistry, Analytical
Xu Li, Jiali Huang, Jiayu Ding, Mingzhen Xiu, Kang Huang, Kang Cui, Jing Zhang, Shiji Hao, Yan Zhang, Jinghua Yu, Yizhong Huang
Summary: In this study, a dual-mode lab-on-paper device was constructed using BiVO4/FeOOH nanocomposites as an efficient photoelectrochemical (PEC)/colorimetric signal reporter for sensitive detection of carcinoembryonic antigen (CEA). The nanocomposites with an FeOOH needle-like structure displayed enhanced PEC response activity, enabling quantitative detection of CEA with the PEC signal readout mode. Additionally, a colorimetric signal readout system was achieved through a smart folding technique, providing a dual-mode signal readout for the lab-on-paper device.
Article
Chemistry, Analytical
Qian Wang, Liang Lv, Wenhao Chi, Yujiao Bai, Wenqing Gao, Peihua Zhu, Jinghua Yu
Summary: A new porphyrin-based porous covalent organic framework (TAP-COF) with high surface areas and efficient electron transport was synthesized. The TAP-COF exhibited excellent peroxidase-like catalytic activity and was able to catalyze the oxidation of a substrate by hydrogen peroxide. Simple and rapid colorimetric methods for in situ hydrogen peroxide detection were developed using this TAP-COF nanozyme, which has potential applications in point-of-care testing, cell biology, and clinical diagnosis.
Article
Chemistry, Analytical
Huihui Shi, Yanfei Che, Yumeng Rong, Jiajun Wang, Yanhu Wang, Jinghua Yu, Yan Zhang
Summary: An integrated dual-signal bioassay was developed for ultrasensitive detection of thrombin. This method combined visualization with photoelectrochemical technique to achieve the detection. The bioassay demonstrated wide linear ranges, high selectivity, stability, and reproducibility under optimized conditions. Additionally, the proposed visual/photoelectrochemical transduction mechanism platform offered a lower background signal and more reliable detection results, providing an effective way for detecting other proteins and nucleic acids.
Article
Chemistry, Analytical
Wenli Xiu, Peini Zhao, Yujie Pan, Xiaoru Wang, Lina Zhang, Shenguang Ge, Jinghua Yu
Summary: A surface-enhanced Raman scattering (SERS) sensor was developed for rapid on-site determination of ethephon in food, based on the folding and assembly characteristics of paper fibers, the skeleton controllability of metal-organic framework materials (MOFs), and the morphology designability of plasmonic noble metal materials. The sensor used HKUST-1(Cu) assembled onto a carbon-treated chromatographic paper matrix to overcome poor affinity of SERS substrate for target molecules. With the coupling of biomimetic antibodies and a multi-stage progressive enhancement structure, the sensor achieved high specificity and sensitivity for ethephon detection with a linear range of 10-3 to 10 mg kg-1 and a low detection limit of around 1.39 x 10-4 mg kg-1.
ANALYTICA CHIMICA ACTA
(2023)
Article
Chemistry, Analytical
Li Shan, Yuanyuan Chen, Xiaoran Tan, Shenguang Ge, Lina Zhang, Lin Li, Jinghua Yu, Li Li
Summary: A newly designed two-in-one tetrahedral DNA (TDN) nanostructure with an antifouling surface and backbone-rigidified interfacial tracks was developed for highly sensitive and selective detection of miRNA-182-5p. The TDN-modified sensing interfaces demonstrated incomparable antifouling ability against protein samples and interfering miRNAs due to the strong hydrophilic capacity and special molecular conformations. The designed TDN-modified paper-based photoelectro-chemical sensor successfully quantified miRNA-182-5p with a low detection limit of 0.09 fM and high specificity in real samples, showing great promise for bioanalysis and clinical diagnosis.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Physical
Shanshan Li, Haihan Yu, Yuwen Wang, Shuai Wang, Lina Zhang, Peihua Zhu, Chaomin Gao, Jinghua Yu
Summary: A stable organic-inorganic Z-scheme heterostructure was constructed by covalently connecting COF-366-Fe and CeO2 through Schiff base reaction, which effectively integrated their respective properties and improved the separation and transfer of photoexcited carriers. The COF-366-Fe@CeO2 exhibited superior photocatalytic CO yield compared to COF-366-Fe and CeO2, indicating its potential as a highly-effective COF-based photocatalyst for artificial photosynthesis.
APPLIED SURFACE SCIENCE
(2023)
Article
Biophysics
Lin Li, Hui Tian, Guofu Wang, Suyue Ren, Tinglei Ma, Yixiang Wang, Shenguang Ge, Yan Zhang, Jinghua Yu
Summary: Ready-to-use in vitro diagnosis is crucial for cervical cancer prevention and treatment. A paper-film-based differential lateral flow biosensor is proposed, allowing simultaneous detection of two high-risk HPV types. The biosensor utilizes a CuCo2S4/ZnIn2S4 heterostructure on a paper-film chip and introduces surface sulfur vacancy for enhanced photoexcitation. Through sequential solution transfer, the biosensor activates the self-assembly of DNA and the cleavage activity of CRISPR-Cas12a, resulting in the release of polydopamine-coated gold nanoparticles. This intelligent biosensor achieves low limit-of-detection for HPV-18 and HPV-16 and provides a promising approach for home medical intelligent diagnosis.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Chemistry, Inorganic & Nuclear
Wenhao Wang, Lu Zhang, Yanli Kang, Xiaodong Yang, Shenguang Ge, Feng Yu
Summary: A TiO2-CoFe2O4 heterostructure was successfully prepared using a hydrothermal method for detecting toluene gas. The heterojunction exhibited a shorter bandgap and inhibited electron-hole pair recombination, leading to improved gas sensitivity. The response value of the heterojunction was significantly higher than that of pure TiO2 and CoFe2O4, especially under UV irradiation. Density functional theory was also applied in this study to explain the improvement in gas sensitivity through material energy band and adsorption energy calculations. This work provides valuable insights for the preparation of high-efficiency and high-sensitivity gas sensors.
DALTON TRANSACTIONS
(2023)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
