Article
Chemistry, Applied
Chen Chen, Ximo Wang, Geoffrey I. N. Waterhouse, Xuguang Qiao, Zhixiang Xu
Summary: A highly sensitive molecularly imprinted surface-enhanced Raman scattering sensor has been developed for selective detection of histamine, showing good linearity and sensitivity. In spiked liquor samples, histamine was accurately detected with high recoveries.
Article
Engineering, Environmental
Shishir Venkatesh, Chi-Chung Yeung, Tan Li, Siu Chuen Lau, Qi-Jun Sun, Ling-Yi Li, Jin Hua Li, Michael H. W. Lam, Vellaisamy A. L. Roy
Summary: Histamine, a naturally occurring chemical in seafood, can cause undesirable inflammatory response when consumed in large amounts, hence the need for guidelines limiting its amount in fresh and processed seafood worldwide. Conventional histamine detection is slow and leads to bottlenecks in the supply chain, highlighting the importance of developing a rapid on-site detection system for seafood suppliers. The impedance-based histamine detection sensor described in the study can detect histamine levels in the range of 100-500 ppm and shows promise for detecting other food contaminants in aqueous solutions.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Materials Science, Multidisciplinary
Yaming Xu, Neng Qin, Zhaosu Liu, Hui Han, Si Yin Tee, Guijian Guan, Ming-Yong Han
Summary: This research achieves molecular imprinting in a highly crystalline inorganic matrix for the first time without the need for additional functional groups. The target molecules have strong multiple interactions with the crystalline matrix, resulting in stronger binding affinities and excellent imprinting effects. The study opens up new possibilities for molecular imprinting in visible light-responsive inorganic matrices.
ACS MATERIALS LETTERS
(2022)
Article
Biochemistry & Molecular Biology
Jihye Lee, Jin Chul Yang, Saifullah Lone, Woon Ik Park, Zhiqun Lin, Jinyoung Park, Suck Won Hong
Summary: This study presents a strategy for producing highly ordered arrays of surface-imprinted polymer patterns for MIP-based sensor platforms, allowing for efficient detection of small molecules. The use of evaporative self-assembly to create familiar yet ordered coffee-ring-like patterns offers a new approach for various applications.
Article
Chemistry, Analytical
Yuanyuan Yang, Yuanting Li, Wenlei Zhai, Xuejian Li, Dan Li, Hualin Lin, Sheng Han
Summary: The study presents a novel approach using molecularly imprinted polymer-based core-shell AuNP@polydopamine nanoparticles for reliable SERS recognition with molecular selectivity and high sensitivity. By combining electrokinetic preseparation and MIP trapping of charged molecules, the interface offers a label-free detection of charged molecules in real samples without pretreatment.
ANALYTICAL CHEMISTRY
(2021)
Review
Chemistry, Analytical
Rocio Arreguin-Campos, Kathia L. Jimenez-Monroy, Hanne Dilien, Thomas J. Cleij, Bart van Grinsven, Kasper Eersels
Summary: Foodborne illnesses have high costs globally, leading to the emergence of technologies in a multidisciplinary context to monitor and improve food preservation for safety along the food chain. These technologies focus on detecting and removing biological or chemical safety hazards, with imprinted polymers being synthetic receptors capable of recognizing contaminants.
Article
Materials Science, Multidisciplinary
Shahzad Ahmed, Arshiya Ansari, Ahmed S. Haidyrah, Anis Ahmad Chaudhary, Mohd Imran, Afzal Khan
Summary: In this study, an electrochemical biosensor for histamine detection was fabricated using a molecularly imprinted polymer. The sensor exhibited high selectivity and sensitivity, with excellent performance in various aspects.
ACS APPLIED POLYMER MATERIALS
(2022)
Article
Chemistry, Analytical
Linlin Wang, Yixin Nie, Peilin Wang, Ying Li, Qiang Ma, Dahai Yu
Summary: In this study, a novel ECL sensor based on bacterial imprinted polymers (BIP) technology was developed for the rapid detection of intestinal probiotics. The sensor exhibited improved analytical performance for bacteria detection and remarkable specific identification of bacterial serotypes.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Analytical
Shanshan Li, Tingting Zhong, Qingxia Long, Cuiping Huang, Liying Chen, Dujuan Lu, Xin Li, Zhiqing Zhang, Guanghui Shen, Xiaoyan Hou
Summary: An electrochemical sensor utilizing molecularly imprinted polymer (MIP) on gold nanoparticles (AuNPs) electrode was developed for histamine (HIS) determination, showing enhanced performance and successful detection in alcoholic beverages. The results were in good agreement with high-performance liquid chromatography (HPLC) method, indicating the reliability and applicability of the proposed methodology for HIS detection in beer and wine samples.
MICROCHEMICAL JOURNAL
(2021)
Article
Polymer Science
Joseph W. Lowdon, Hanne Dilien, Bart van Grinsven, Kasper Eersels, Thomas J. Cleij
Summary: The research focuses on developing a dye displacement assay based on MIP for colorimetric detection of the antibiotic amoxicillin in aqueous medium. The study includes developing an MIP through monolithic bulk polymerization and utilizing emulsion polymerization for more homogenous particle synthesis. The assay demonstrates high specificity and selectivity towards amoxicillin, offering a rapid semi-quantitative detection method.
Review
Polymer Science
Celia Cabaleiro-Lago, Sylwia Hasterok, Anette Gjoerloff Wingren, Helena Tassidis
Summary: Molecularly imprinted polymers (MIPs) and the imprinting technique provide polymeric material with recognition elements similar to natural antibodies. This review discusses the promising clinical applications of different MIP systems recently developed for disease diagnosis and treatment.
Article
Chemistry, Analytical
Yingjie Zhao, Li Tian, Xin Zhang, Zhuo Sun, Xiangyu Shan, Qian Wu, Ruizhan Chen, Juan Lu
Summary: A specificity recognition molecularly imprinted electrochemiluminescence sensor (MIECLS) for determination of clenbuterol (CLB) was established, with a detection limit of 3.3 x 10(-10) mol L-1. The sensor utilized Fe2O3 as the carrier to fix Ru(bpy)(3)(2+), and introduced molecular imprinted membranes (MIPs) with CLB as template molecules to achieve specificity identification, showing great potential in pork and liver samples testing.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Applied
Madanodaya Sundhoro, Srikanth R. Agnihotra, Brent Amberger, Keenan Augustus, Nazir D. Khan, Abigail Barnes, Joseph BelBruno, Lukasz Mendecki
Summary: Food allergies are a serious public health concern, and rapid detection of allergenic ingredients using molecularly imprinted polymers could greatly improve the quality of life for allergy sufferers. The MIP sensor demonstrated in this study is capable of detecting allergenic soy markers at concentrations as low as 100 parts-per-billion, providing a potential solution to the challenge of direct allergen detection in food analysis.
Article
Polymer Science
Xin Zhang, Pengfei Jiao, Yihan Ma, Yuping Wei
Summary: A new fluorescence sensor based on molecular imprinted polymers was designed by combining them with water-soluble manganese-doped zinc sulfide quantum dots (Mn2+: ZnS QDs). The sensor, known as MIP@QDs, showed rapid and selective fluorescence sensing of sulfanilamide in water samples. The experimental results demonstrated that the MIP@QDs has high selectivity and sensitivity towards sulfanilamide detection, with a quick response time of 5 minutes and an imprinting factor of 14.8.
Article
Chemistry, Analytical
Anggy Lusanna Gutierrez-Ortiz, Veronica Vida, Matjaz Peterka, Jasmina Tusar, Federico Berti, Luciano Navarini, Cristina Forzato
Summary: In this study, fluorescent polymeric imprinted nanoparticles were synthesized for selective binding of chlorogenic acid in coffee extract. The immobilization of nanoparticles on a functionalized glass surface allowed for fluorescence measurement of chlorogenic acid concentration.
Article
Chemistry, Multidisciplinary
Sudhirkumar Shinde, Anil Incel, Mona Mansour, Gustaf D. Olsson, Ian A. Nicholls, Cem Esen, Javier Urraca, Boerje Sellergren
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2020)
Article
Chemistry, Physical
Stefan Kuczera, Axel Ruter, Kevin Roger, Ulf Olsson
Article
Chemistry, Multidisciplinary
Alessandra Del Giudice, Axel Ruter, Nicolae Viorel Pavel, Luciano Galantini, Ulf Olsson
Article
Biochemistry & Molecular Biology
Mona Koder Hamid, Axel Ruter, Stefan Kuczera, Ulf Olsson
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2020)
Article
Polymer Science
Tjasa Gornik, Sudhirkumar Shinde, Lea Lamovsek, Maja Koblar, Ester Heath, Borje Sellergren, Tina Kosjek
Summary: This study demonstrated the potential of molecularly imprinted polymers as sorbents for removing SSRIs in water treatment, with optimized composition to achieve highest capacity, affinity, and selectivity. The MIPs showed stable performance, reusability, and superior sorption capabilities in wastewaters, making them better suited for use in wastewater treatment.
Article
Chemistry, Multidisciplinary
Zahra El-Schich, Yuecheng Zhang, Tommy Goransson, Nishtman Dizeyi, Jenny L. Persson, Emil Johansson, Remi Caraballo, Mikael Elofsson, Sudhirkumar Shinde, Borje Sellergren, Anette Gjorloff Wingren
Summary: Sialylations are crucial post-translational modifications in cellular events, especially in tumor cells where high levels of sialic acid (SA) expression are associated with increased invasive potential. The use of SA-MIPs as nanoprobes shows promise in detection and analysis of breast cancer cells.
APPLIED SCIENCES-BASEL
(2021)
Article
Biotechnology & Applied Microbiology
Theyencheri Narayanan, Axel Ruter, Ulf Olsson
Summary: This brief report presents an X-ray scattering investigation of self-assembled nanotubes formed by a short peptide, demonstrating the quantitative determination of nanotube dimensions and crystalline organization within their walls, using amyloid-beta(16-22) peptide nanotubes as an illustrative example.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Theyencheri Narayanan, Axel Ruter, Ulf Olsson
Summary: This review explores the structural investigations of self-assembled peptide nanotubes using X-ray scattering techniques. Compared to electron microscopy, scattering methods allow for studies of nanotubes in solution under the right physicochemical conditions and probe their formation mechanisms. Additionally, a combination of X-ray scattering methods enables the elucidation of structural organization from the molecular scale to the nanotube dimension.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Liliia Mavliutova, Elena Verduci, Sudhirkumar A. Shinde, Borje Sellergren
Summary: Aberrant glycosylation is linked to various diseases such as cancer, with sialic acid playing a key role in tumor-specific glycans. The development of molecularly imprinted polymers (MIPs) with high affinity for sialic acids is crucial for early cancer diagnosis. This study investigates the cooperative covalent/noncovalent imprinting approach for glycospecific MIPs, showing enhanced imprinting factors and selectivities by using three functional monomers and highlighting the importance of template counterions.
Article
Biochemistry & Molecular Biology
Yohannes Abere Ambaw, Sandra Rinne Dahl, Yan Chen, Tyge Greibrokk, Elsa Lundanes, Issam Lazraq, Sudhirkumar Shinde, Jayashree Selvalatchmanan, Markus R. Wenk, Borje Sellergren, Federico Torta
Summary: The study presents a rapid and selective extraction method using new low-cost molecularly imprinted and non-imprinted polymeric sorbents for lipid mediators from plasma and tissue samples. The method was validated by quantifying lipid mediators through liquid chromatography-tandem mass spectrometry, demonstrating advantages in extraction efficiency and reduction of non-specific interactions.
Article
Materials Science, Multidisciplinary
Mona Rouhi, Anil Incel, Sudhirkumar Shinde
Summary: This study presents a method for synthesizing a water-compatible oxyanion-imprinted neutral receptor and demonstrates its practical applications in solid-phase extraction and amino acid binding in aqueous media.
ACS APPLIED POLYMER MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Sudhirkumar Shinde, Mona Mansour, Liliia Mavliutova, Anil Incel, Celina Wierzbicka, Hussein Abdel-Shafy, Borje Sellergren
Summary: The study involved polymerizable hosts in anion imprinting to create receptors with high oxyanion affinity and specificity in both aqueous and non-aqueous environments. By comparing hydrophobic and hydrophilic crosslinking monomers, optimal conditions for oxyanion binding in different media were identified.
Article
Chemistry, Multidisciplinary
Thomas Hix-Janssens, Sudhirkumar Shinde, Rahma Abouhany, Julia Davies, Jessica Neilands, Gunnel Svensaeter, Boerje Sellergren
Summary: Periodontitis is a common oral condition that affects around 7% of adults and has potential links to cardiovascular and Alzheimer's diseases. The lack of accurate clinical methods for identifying at-risk patients leads to both underdiagnosis and overtreatment. Researchers have developed a monitoring approach using high-affinity microcontact imprinted polymer-based receptors and surface plasmon resonance-based biosensor technology to quantify gingipain levels, which are key virulence factors in periodontitis, in biofluids and patient samples.
Article
Biochemical Research Methods
Giuliana Grasso, Eduardo M. Sommella, Fabrizio Merciai, Rahma Abouhany, Sudhirkumar A. Shinde, Pietro Campiglia, Borje Sellergren, Carlo Crescenzi
Summary: In this study, three novel polymeric capture phases were developed for the selective extraction of a biomarker and its analogue drug related to neurodegenerative diseases. The results demonstrated high affinity of the sorbents towards the biomarker and drug. This approach offers a valuable tool for developing efficient analytical procedures.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Physical
Axel Rueter, Stefan Kuczera, Joakim Stenhammar, Thomas Zinn, Theyencheri Narayanan, Ulf Olsson
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2020)