期刊
SEMINARS IN PEDIATRIC SURGERY
卷 26, 期 3, 页码 154-158出版社
ELSEVIER SCIENCE INC
DOI: 10.1053/j.sempedsurg.2017.04.001
关键词
Congenital diaphragmatic hernia; Pulmonary hypertension; Cardiac function; Echocardiography; Diastolic; Systolic
Cardiac dysfunction is an important consequence of pulmonary hypertension in congenital diaphragmatic hernia and a determinant of disease severity. Increased afterload leads to right ventricular dilatation and diastolic dysfunction. Septal displacement and dysfunction impair left ventricular function, which may also be compromised by fetal hypoplasia. Biventricular failure contributes to systemic hypotension and hypoperfusion. Early and regular echocardiographic assessment of cardiac function and pulmonary artery pressure can guide therapeutic decision-making, including choice and timing of pulmonary vasodilators, cardiotropes, ECMO, and surgery. (C) 2017 Elsevier Inc. All rights reserved.
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