Article
Neurosciences
Kharma C. Foucher, Chun-Hao Huang, Burcu Aydemir
Summary: The study revealed that greater energy used during walking was associated with lower self-reported physical activity, while lower hip abductor strength was linked to decreased physical activity. Together, these variables could predict 55.5% of the variance in self-reported physical activity, indicating potential intervention targets to promote physical activity in this population.
Article
Orthopedics
P. Corrigan, T. Neogi, L. Frey-Law, S. R. Jafarzadeh, N. Segal, M. C. Nevitt, C. E. Lewis, J. J. Stefanik
Summary: This study aimed to investigate the relationship between pain sensitization and poor physical functioning in individuals with knee osteoarthritis (OA). The results showed that heightened pain sensitivity was associated with worse self-reported function and slower walking speed. However, its impact on performance-based function was minimal.
OSTEOARTHRITIS AND CARTILAGE
(2023)
Article
Rehabilitation
Hiroshige Tateuchi, Masahide Yagi, Haruhiko Akiyama, Koji Goto, Kazutaka So, Yutaka Kuroda, Noriaki Ichihashi
Summary: The study aimed to identify muscle function-based clinical phenotypes in patients with hip osteoarthritis (OA) and determine their association with disease progression. The findings suggest that phenotypes based on muscle strength balance may be associated with disease progression.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2023)
Article
Geriatrics & Gerontology
Rikke S. Kamper, Julian Alcazar, Lars L. Andersen, Bryan Haddock, Niklas Rye Jorgensen, Peter Hovind, Charlotte Suetta
Summary: The study investigated the relationship between chronic low-grade inflammation and age-related muscle decline and physical performance. Results showed that with age, levels of certain inflammatory biomarkers in the blood increased significantly, correlating with decreased muscle strength and physical function.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2021)
Article
Orthopedics
Junya Sekita, Naonobu Takahira, Genki Iwamura, Hiroyuki Watanabe, Atsushi Kusaba, Saiji Kondo
Summary: The study focused on female patients with hip osteoarthritis and found that preoperative muscle strength, age, weight, physical activity, and disease duration are significant factors affecting postoperative muscle strength, with the impact of preoperative muscle strength on knee extensor strength depending on age.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Review
Medicine, General & Internal
Ji-Qian Wu, Xin-Chong Che
Summary: This study aims to investigate the therapeutic effects of isokinetic muscle strength training on improving muscle function in patients with knee osteoarthritis. Data will be collected from various databases and quality assessment and risk assessment will be conducted to provide accurate results and conclusions.
Article
Rehabilitation
Allison Schroeder, Na Wang, David T. Felson, Cora E. Lewis, Michael C. Nevitt, Neil A. Segal
Summary: The study aimed to investigate the association between variability in peak knee flexor and extensor torque and worsening of knee pain and physical function. Results indicated that patients with greater variability in knee flexor torque were more likely to experience worsening pain and physical function, suggesting that this factor could help identify patients who may benefit from targeted therapies.
AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION
(2021)
Article
Orthopedics
Burcu Aydemir, Chun-Hao Huang, Kharma C. Foucher
Summary: The study found that the association between muscle strength and physical activity level in individuals with knee osteoarthritis is mediated by kinesiophobia, rather than pain. Knee extension strength is directly related to physical activity level, suggesting that muscle strength can influence physical activity indirectly or directly.
JOURNAL OF ORTHOPAEDIC RESEARCH
(2022)
Article
Geriatrics & Gerontology
Mengyu Cao, Junsong Lian, Xisheng Lin, Jinwei Liu, Chao Chen, Shuaixuan Xu, Shuang Ma, Fang Wang, Nihui Zhang, Xiaolei Qi, Guogang Xu, Nan Peng
Summary: This study investigates the consistency between the latest diagnostic criteria for sarcopenia, AWGS 2019, and other common criteria in China. The study also analyzes the changes in muscle mass, muscle strength, and physical function with age and their impact on sarcopenia diagnosis. The results show that AWGS 2019 is highly consistent with other criteria and that the effects of age on muscle strength and function are more significant than on muscle mass.
Review
Geriatrics & Gerontology
Pedro Lopez, Anderson Rech, Maria Petropoulou, Robert U. Newton, Dennis R. Taaffe, Daniel A. Galvao, Douglas J. P. Turella, Sandro R. Freitas, Regis Radaelli
Summary: This study conducted a systematic review and network meta-analysis to examine the effectiveness of different resistance exercise velocity modes in older adults. The results showed that high-velocity resistance exercise was most effective for improving fast walking speed, timed-up and go, and 5-times sit-to-stand, while traditional resistance exercise was most effective for 30-second sit-to-stand and 6-minute walking. Therefore, individualized prescriptions based on contraction velocity should be used to address specific functional needs.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Multidisciplinary Sciences
Chong Kim, Kathryn L. Colborn, Stef van Buuren, Timothy Loar, Jennifer E. Stevens-Lapsley, Andrew J. Kittelson
Summary: This study developed and tested personalized predictions for functional recovery after Total Knee Arthroplasty surgery using a novel neighbors-based prediction approach. Predictions were generated by estimating a patient's prognosis from the observed recovery data of similar patients, and the optimal number of matches was determined based on low bias, accurate coverage, and acceptable precision. The predictions were well-calibrated in out-of-sample testing, showing potential to guide care decisions both before and after TKA surgery.
SCIENTIFIC REPORTS
(2021)
Article
Rehabilitation
Andrew Hislop, Natalie J. Collins, Kylie Tucker, Adam Semciw
Summary: This study found that there is an association between multidirectional hip strength and physical function and balance in people with knee osteoarthritis. Hip strength is strongly related to physical function and dynamic balance, and clinicians should consider multidirectional hip strength when developing exercise programs for patients with knee osteoarthritis.
MUSCULOSKELETAL SCIENCE AND PRACTICE
(2023)
Article
Pharmacology & Pharmacy
Cristiano Carvalho, Fabio Viadanna Serrao, Leticia Mancini, Paula Regina Mendes da Silva Serrao
Summary: The study found that individuals with isolated patellofemoral osteoarthritis (PFOA) exhibit impairments in muscle capacity of the knee and hip, as well as higher levels of pain, stiffness, and compromised physical functioning compared to healthy controls.
THERAPEUTIC ADVANCES IN CHRONIC DISEASE
(2021)
Article
Cardiac & Cardiovascular Systems
Valentina Muollo, Toni Tatangelo, Laura Ghiotto, Valentina Cavedon, Chiara Milanese, Mauro Zamboni, Federico Schena, Andrea P. Rossi
Summary: This study investigated the association between handgrip strength and muscle function of the lower limbs, as well as predictors of appendicular lean mass index in older adults with obesity. Results showed that handgrip strength was weakly associated with lower limbs muscle function and physical performance, while BMI was a significant predictor for ALMI in both genders. In the group of men, markers related to strength and power of the lower limbs were found to better explain variations in ALMI compared to handgrip strength.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2022)
Article
Physiology
Sara A. Harper, Brennan J. Thompson
Summary: Assessing neuromuscular capacity in older adults is crucial for determining age-related functional decline risks; Minimal dose eccentric resistance training can improve muscle quality and functional performance in older adults; Improved exercise tolerance may enhance exercise participation and overall health in older adult populations.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Orthopedics
Anthony Hipsley, Michelle Hall, David J. Saxby, Kim L. Bennell, Xinyang Wang, Adam L. Bryant
Summary: Quadriceps strength deficits following anterior cruciate ligament reconstruction (ACLR) are associated with cartilage volume changes. In the early years after ACLR, higher quadriceps strength is correlated with lower cartilage volume on the medial tibia. Restoring quadriceps strength may reduce the likelihood of early tibiofemoral joint cartilage degeneration.
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
(2022)
Article
Rehabilitation
Kelly J. Bower, Shamala Thilarajah, Gavin Williams, Yong-Hao Pua, Dawn Tan, Ross A. Clark
Summary: The study aimed to examine the validity, predictive ability, and responsiveness of standing centre of pressure variables in subacute stroke patients. The results showed that some centre of pressure variables were moderately correlated with gait speed and step test scores, and also predicted falls risk. However, the standing centre of pressure variables had limited validity in reflecting dynamic balance and falls risk.
DISABILITY AND REHABILITATION
(2023)
Review
Rheumatology
Yuri Lopes Lima, Hopin Lee, David M. Klyne, Fiona L. Dobson, Rana S. Hinman, Kim L. Bennell, Michelle Hall
Summary: This scoping review identified potential mediators of nonsurgical interventions on pain and physical function in knee osteoarthritis. Variables such as body weight, systemic inflammation, knee muscle strength, and self-efficacy were found to partially mediate the effects of interventions such as diet plus exercise, exercise, and high-expectation communication.
ARTHRITIS CARE & RESEARCH
(2023)
Article
Medicine, General & Internal
Kim L. Bennell, Sarah Schwartz, Pek Ling Teo, Stephanie Hawkins, Dave Mackenzie, Fiona McManus, Karen E. Lamb, Alexander J. Kimp, Ben Metcalf, David J. Hunter, Rana S. Hinman
Summary: The study evaluated the effectiveness of an unsupervised 12-week online yoga program for knee osteoarthritis, showing that yoga improved physical function but had less significant effects on knee pain during walking, and the benefits were not sustained after 24 weeks.
ANNALS OF INTERNAL MEDICINE
(2022)
Article
Rehabilitation
Yong-Hao Pua, Cheryl Lian-Li Poon, Felicia Jie-Ting Seah, John Wei-Ming Tan, Ee-Lin Woon, Hwei-Chi Chong, Julian Thumboo, Ross Allan Clark, Seng-Jin Yeo
Summary: After total knee arthroplasty, the improvement of quadriceps strength and gait speed can be better interpreted by examining trajectory curves across levels of self-reported walking and stair climbing function. The study found that quadriceps strength and gait speed improved nonlinearly over time, and greater improvements were associated with higher levels of self-reported walking and stair climbing function at month-6. It was observed that among female patients with great difficulty in stair ascent and ambulation, quadriceps strength trajectory curves plateaued after 8 weeks post-surgery.
AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION
(2023)
Article
Sport Sciences
Rana S. Hinman, Michelle Hall, Sarah Comensoli, Kim L. Bennell
Summary: This update Position Statement provides the most recent evidence and guidance for health practitioners managing people with hip/knee osteoarthritis, emphasizing the importance of exercise in reducing joint pain, increasing physical function, and improving quality of life. Exercise dosage should be guided by the principles of the American College of Sports Medicine, and practitioners should actively monitor and promote adherence to exercise for optimal therapeutic benefits.
JOURNAL OF SCIENCE AND MEDICINE IN SPORT
(2023)
Article
Nutrition & Dietetics
Yong-Hao Pua, Laura Tay, Ross Allan Clark, Julian Thumboo, Ee-Ling Tay, Shi-Min Mah, Yee-Sien Ng
Summary: In older adults with no self-reported mobility limitations, height, weight, and body mass index (BMI) were found to be significantly associated with handgrip strength, with height showing the strongest association.
CLINICAL NUTRITION ESPEN
(2023)
Article
Orthopedics
Yong-Hao Pua, Bryan Yijia Tan, Juanita Low, Ee-Lin Woon, Seng-Jin Yeo, Ross A. Clark, Janet P. Bettger, Michelle J. Pereira, Chun-Yue Tan, Julian Thumboo
Summary: This study aimed to examine the association between pain, negative affect (anxiety and depression), and the discordance between self-reported measures and performance-based measures of physical function. The results showed that knee pain intensity was strongly associated with the discordance, while anxiety had a weak association, and depression had no significant association with the discordance.
JOURNAL OF ARTHROPLASTY
(2023)
Article
Public, Environmental & Occupational Health
Ziying Wu, Yilun Wang, Yuqing Zhang, Kim L. Bennell, Daniel K. White, Liusong Shen, Wei Ren, Jie Wei, Chao Zeng, Guanghua Lei
Summary: The COVID-19 pandemic has caused a decline in daily steps and physical activity levels. Studies show that over 7000 steps per day is the minimum standard for reducing the risk of all-cause mortality. The confinement period of COVID-19 has led to a significant decrease in daily steps among the general adult population.
JMIR PUBLIC HEALTH AND SURVEILLANCE
(2023)
Article
Rehabilitation
Aileen E. E. Scully, Dawn Tan, Beatriz Ito Ramos de Oliveira, Keith D. D. Hill, Ross Clark, Yong Hao Pua
Summary: A new clinician-rated tool (FOG Severity Tool-Revised) was developed to improve the assessment of freezing of gait (FOG) severity. This study investigated the validity and reliability of the tool in people with Parkinson's disease. The FOG Severity Tool-Revised demonstrated sufficient validity and reliability in this limited sample.
PHYSIOTHERAPY RESEARCH INTERNATIONAL
(2023)
Article
Geriatrics & Gerontology
Yong-Hao Pua, Laura Tay, Berend Terluin, Ross Allan Clark, Julian Thumboo, Ee-Ling Tay, Shi-Min Mah, Yee-Sien Ng
Summary: This study compared the clinical cutpoints of gait speed and 5-STS estimated using the ROC and APM methods. The results showed that the APM method provided more accurate cutpoints, which were closely related to self-reported walking difficulty, stair climbing difficulty, and mobility limitations.
ARCHIVES OF GERONTOLOGY AND GERIATRICS
(2023)
Article
Rehabilitation
Aileen Eugenia Scully, Dawn May Leng Tan, Beatriz IR. de Oliveira, Keith David Hill, Ross Clark, Yong Hao Pua
Summary: This study aims to investigate the validity and reliability of the Freezing of Gait Severity Tool (FOG Tool). After conducting a series of assessments on people with Parkinson's disease, it was found that the FOG Tool had strong associations with the Freezing of Gait Questionnaire and excellent test-retest reliability. Compared to the Timed Up and Go (TUG), the FOG Tool was more successful in triggering freezing.
DISABILITY AND REHABILITATION
(2023)
Article
Rehabilitation
Kenth Louis Joseph, Hanne Dagfinrud, Kare Birger Hagen, Kristine Roren Norden, Camilla Fongen, Ole-Martin Wold, Rana S. Hinman, Rachel K. Nelligan, Kim L. Bennell, Anne Therese Tveter
Summary: This study aimed to describe adherence to a 12-week web-based aerobic exercise program in patients with hip or knee osteoarthritis, compare characteristics between adherent and non-adherent individuals, and identify barriers for exercising. Results showed that half of the patients adhered to the program, and the most frequently reported barrier was sickness.
JOURNAL OF REHABILITATION MEDICINE
(2023)
Article
Geriatrics & Gerontology
Yong-Hao Pua, Berend Terluin, Laura Tay, Ross Allan Clark, Julian Thumboo, Ee-Ling Tay, Shi-Min Mah, Yee-Sien Ng
Summary: This study introduces and demonstrates the utility of an item response theory (IRT) method in estimating frailty index (FI) interpretation thresholds in community-dwelling adults, providing a new tool and reference for defining frailty.
ARCHIVES OF GERONTOLOGY AND GERIATRICS
(2024)
Article
Rheumatology
Belinda J. Lawford, Kim L. Bennell, Michelle Hall, Thorlene Egerton, Fiona McManus, Karen E. Lamb, Rana S. Hinman
Summary: The addition of an option grid and GP exercise recommendation to general OA information led to more favorable views that exercise was the best management option for the hypothetical knee problem, although the differences were small and of unclear clinical importance.
ACR OPEN RHEUMATOLOGY
(2023)
Article
Rheumatology
Walter P. Maksymowych, Nele Herregods, Nisha Varma, Arthur B. Meyers, Jennifer Stimec, Andrea S. Doria, Nikolay Tzaribachev, Tarimobo M. Otobo, Marion A. van Rossum, Joel Paschke, Stephanie Wichuk, Robert G. Lambert
Summary: This study aimed to investigate whether systematic calibration improves the scoring proficiency of JAMRIS-SIJ and whether contrast-enhancement enhances its performance. The results showed that calibrated readers achieved greater reliability in scoring specific inflammatory and structural lesions. Sensitivity and reliability for scoring inflammatory lesions were higher on fluid-sensitive sequences compared to contrast-enhanced sequences. Therefore, systematic calibration should be implemented before using JAMRIS-SIJ in clinical trials, and it is unlikely that contrast-enhanced MRI will improve the performance of this method.
SEMINARS IN ARTHRITIS AND RHEUMATISM
(2024)
Article
Rheumatology
L. van Ouwerkerk, S. A. Bergstra, T. D. Maarseveen, T. W. J. Huizinga, R. Knevel, C. F. Allaart
Summary: This study evaluated whether the initial use of glucocorticoid (GC) bridging in RA patients leads to a higher probability of long-term GC and bDMARD use. The results showed that patients who initially started GC had a higher risk of later GC use, but the risk of bDMARD use was not significantly increased.
SEMINARS IN ARTHRITIS AND RHEUMATISM
(2024)
Article
Rheumatology
ShuangHua Liu, YiMei Tan, WeiDong Huang, HongSheng Luo, BingCheng Pan, Shuan Wu
Summary: This study assessed the cardiovascular safety of zoledronic acid in the treatment of primary osteoporosis. The results showed that in women with primary osteoporosis, zoledronic acid may increase the risk of atrial fibrillation and arrhythmias, but the cardiovascular risk in men with osteoporosis is uncertain.
SEMINARS IN ARTHRITIS AND RHEUMATISM
(2024)