Article
Green & Sustainable Science & Technology
Ke Ren, Tianzuo Zhang, Xianfeng Tan, Yijie Zhai, Yueyang Bai, Xiaoxu Shen, Yuke Jia, Jinglan Hong
Summary: This study analyzed the environmental performance of mainstream ammonia synthesis in China using the LCA method, and found that the pulverized coal entrained flow gasification technology showed superiority in reducing the environmental burden, especially in categories such as global warming, freshwater ecotoxicity, and water depletion.
JOURNAL OF CLEANER PRODUCTION
(2021)
Article
Environmental Sciences
Jing Liu, Yu Zhuang, Chao Wang, Jian Du
Summary: The coal-to-synthetic natural gas (SNG)/methanol polygeneration process can solve the problems of the coal-to-natural gas project and achieve carbon emission reduction.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Green & Sustainable Science & Technology
Lufan Li, Xin Shao, Tung-Chai Ling
Summary: Cement production contributes to CO2 emissions, but solid wastes can replace cement clinker to produce composite cements with lower carbon footprints. However, existing life cycle assessment (LCA) studies often overlook the environmental burden from upstream processes and strength degradation after replacing cement. This study comprehensively compares the environmental performance of different composite cements through LCA, and recommends ternary composite cement and a calcination temperature of 600℃ as the optimal choices.
JOURNAL OF CLEANER PRODUCTION
(2023)
Article
Engineering, Environmental
Mateus Guimaraes da Silva, Antonio Carlos Luz Lisboa, Ronaldo Hoffmann, Pedro Daniel da Cunha Kemerich, Willian Fernando de Borba, Gabriel D'avila Fernandes, Ericklis Edson Boito de Souza
Summary: This study presents the first environmental impact assessment of rice straw methanol life cycle in Brazil, with focus on emissions from different stages of production process. Results show that removing rice straw from the field can reduce methane emissions but increase nitrous oxide and carbon dioxide emissions. The carbon footprint of rice straw methanol production is 8.09 x 10(-01) kg CO2eq per kg methanol, with biomethanol having the potential to reduce GHG emissions by 67-74% compared to fossil methanol.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2021)
Article
Thermodynamics
York Castillo Santiago, Aldemar Martinez Gonzalez, Osvaldo J. Venturini, Leandro A. Sphaier, Eric A. Ocampo Batlle
Summary: An energetic and environmental assessment of producer gas production from oil sludge gasification was conducted, and its potential use for electricity generation was analyzed. The results showed that oxygen gasification produced a higher gas LHV and achieved greater reductions in nonrenewable energy, respiratory organics, and carcinogens compared to air/steam gasification. The gasification system also had a lower carbon footprint compared to the incineration process.
Article
Thermodynamics
Changyifan Ren, Dianqi Hu, Yunan Chen, Liejin Guo
Summary: An auto-thermal supercritical water co-gasification system was developed for H2 and heat production from sewage sludge and coal. Thermodynamic analysis and life cycle environmental impact assessment were performed, showing the sensitivity of H2 yield to the proportion of preheated water and dry coal to dry sewage sludge. Adding 21% dry coal was necessary when the system was energy self-sufficient to treat sewage sludge directly.
ENERGY CONVERSION AND MANAGEMENT
(2023)
Article
Chemistry, Physical
Mehmet Utku Ozturk, Azize Ayol, Ozgun Tezer
Summary: Biomass gasification is an important renewable energy option for addressing environmental issues caused by fossil fuels and climate change. This study assessed the environmental impacts of olive pomace gasification for electricity generation, including the evaluation of its by-products biochar and tar. The analysis results show that the scenarios have very low impact values, particularly when biochar is beneficially used in different industries.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2023)
Article
Green & Sustainable Science & Technology
Ye Feng, Bo Yang, Yunbing Hou, Tian-Hong Duan, Lai Yang, Yixuan Wang
Summary: This study assessed the environmental impacts of UGCC with and without CCS through life cycle assessment, revealing that UGCC power plants have lower mid-point impact values but higher global warming potential compared to IGCC power plants. Additionally, UGCC power plants show superior end-point environmental benefits, but the implementation of CCS may result in an increase in damage to ecosystem quality and resources.
JOURNAL OF CLEANER PRODUCTION
(2021)
Article
Energy & Fuels
Yunqi Sun, Shuo Wang, Qing Yang, Jianlan Li, Liang Wang, Shihong Zhang, Haiping Yang, Hanping Chen
Summary: This study establishes a process-based model to assess the life cycle VOC emissions of a biomass gasification power plant in China. The results show that the implementation of air pollution control devices can significantly reduce VOC emissions in biomass gasification power generation. It is of great significance for the accurate control of VOC emissions in this technology.
Article
Chemistry, Physical
Huan Liu, Shuqin Liu
Summary: This study compares energy consumption and greenhouse gas emissions between underground coal gasification (UCG)-based hydrogen production (UCG-H-2) and surface coal gasification (SCG)-based hydrogen production (SCG-H-2) using life cycle assessment. Results show UCG-H-2 has significant energy saving advantage, and 80% capture rate can achieve a balance between energy consumption and emissions. Scenario analysis suggests UCG substitution for hydrogen production can reduce energy consumption significantly.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2021)
Article
Agricultural Engineering
Adrian Chun Minh Loy, Hatem Alhazmi, Serene Sow Mun Lock, Chung Loong Yiin, Kin Wai Cheah, Bridgid Lai Fui Chin, Bing Shen How, Suzana Yusup
Summary: This study examined the environmental footprints of H-2 production via catalytic gasification of wheat straw using straw-derived biochar catalysts. The hot spots in the process were identified, with product separation unit (P4) having the greatest environmental impact. The proposed biochar catalyst showed similar catalytic performance with metal-based catalysts but with lower environmental impact, as indicated by benchmarking analysis.
BIORESOURCE TECHNOLOGY
(2021)
Article
Thermodynamics
Kexin Yin, Ranran Wei, Jiuxu Ruan, Peizhe Cui, Zhaoyou Zhu, Yinglong Wang, Xinling Zhao
Summary: This study proposes a multi-objective assessment method to evaluate the entire life cycle of medical supplies, focusing on surgical masks, from an environmental and economic perspective. The results show that the energy consumption and environmental impacts are mainly concentrated in the collection, pretreatment, gasification, and waste heat recovery stages. Operating costs have a significant impact and using automatic equipment and improving energy consumption are crucial for reducing system costs.
Article
Green & Sustainable Science & Technology
Antonella Petrillo, Marta Travaglioni, Simona Di Fraia, Laura Vanoli, Domenico Cirillo, Maurizio La Villetta
Summary: This study presents an Italian case study of a pilot micro-trigeneration plant based on the gasification of wood chips and residual lignocellulosic biomass. Using Life Cycle Assessment techniques, the study provides an estimation of resource consumption and emissions from energy recovery. The results show that greenhouse gas emissions are very low, indicating that biomass can be considered a renewable source and a sustainable alternative to fossil fuels.
JOURNAL OF CLEANER PRODUCTION
(2021)
Article
Engineering, Environmental
Hanqiao Liu, Tong Liu, Guoxia Wei, Hailong Zhao, Tong Li, Fangkai Weng, Xin Guo, Yanzhang Wang, Yanfei Lin
Summary: This study compares economically-affordable and environmentally-friendly rural domestic waste treatment models with different gasification scales through life cycle assessment and life cycle cost analysis. The findings show that the county model has the smallest overall environmental impact, while the town model has the lowest economic cost.
Article
Environmental Sciences
Dongseong Kang, Jeehoon Han
Summary: Through a rigorous life cycle assessment, a technological scenario for producing methanol from blast furnace gas and natural gas was evaluated. The new scenario performed better in most environmental impact categories, except for fossil resource depletion. The robustness of the assessment results is dependent on the primary source used for energy generation displacement.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Green & Sustainable Science & Technology
Katarzyna Widera, Jacek Grabowski, Adam Smolinski
Summary: This paper presents the research results on the composition of ashes obtained from the combustion of fuel samples with various admixtures of waste materials. A statistical model based on discriminant analysis was constructed to identify the markers in the ash samples and indicate their contamination levels. The study found that five chemical elements, namely K, Ti, Zn, Ca, and Rb, have the highest discrimination ability and are the best indicators of contamination level.
Article
Engineering, Chemical
Artur Wodolazski, Adam Smolinski
Summary: This research investigates the modelling and simulation of biomass anaerobic dark fermentation in bio-hydrogen production in a continuous plug flow reactor. The study examines the effects of various factors, such as hydraulic retention time, pH, and feed rate, on the bio-hydrogen yield and production rates. The research also highlights the importance of metabolite proportions in influencing the efficiency of bio-hydrogen production.
Article
Energy & Fuels
Dorota Burchart, Magdalena Gazda-Grzywacz, Przemyslaw Grzywacz, Piotr Burmistrz, Katarzyna Zarebska
Summary: The gasification of Polish coal to produce hydrogen can help Poland become independent of oil and gas imports and facilitate the transition from gray to green hydrogen.
Article
Thermodynamics
Janusz Zdeb, Natalia Howaniec, Adam Smolinski
Summary: Mineralization of carbon dioxide using alkaline earth metals rich waste provides the opportunity for both carbon dioxide utilization and waste valorization. This study presents the results of an experimental investigation on a dry, direct carbonation method using bituminous coal derived fluidized bed fly ash under ambient conditions. The porous structure parameters of the process product were analyzed.
Article
Multidisciplinary Sciences
Jozef Dubinski, Bartlomiej Jura, Janusz Makowka, Tomasz Janoszek, Jacek Skiba, Robert Hildebandt, Adam Duda, Natalia Howaniec, Adam Smolinski
Summary: This paper presents an innovative hydro-cutting technology for bituminous coal excavation, and analyzes its effectiveness through in-situ experiments and modeling. The results show that the distance between the water nozzle outlet and sidewall, water jet pressure, and nozzle type significantly affect hydro-mining effectiveness. Experimental tests in a Polish coal mine demonstrate that water pressure in the range of 20-40 MPa has only a minor impact on coal structure, while high pressure of 80-100 MPa significantly affects it. The tests also reveal the importance of operating time and water jet distance in coal excavation effectiveness.
SCIENTIFIC REPORTS
(2023)
Article
Energy & Fuels
Pawel Baran, Stanislaw Koziol, Katarzyna Czerw, Adam Smolinski, Katarzyna Zarebska
Summary: This study investigates the sorption-dilatometric properties of hard coal samples with different vitrinite and inertinite content. The results show that the petrographic composition affects the behavior of the coal structure, leading to differences in the sorption-dilatometric properties.
Article
Biochemistry & Molecular Biology
Andrzej Bak, Jiri Kos, Gilles Degotte, Aleksandra Swietlicka, Tomas Strharsky, Dominika Pindjakova, Tomas Gonec, Adam Smolinski, Pierre Francotte, Michel Frederich, Violetta Kozik, Josef Jampilek
Summary: A series of 4-chlorocinnamanilides and 3,4-dichlorocinnamanilides were investigated for their antiplasmodial activity, and 23 compounds showed IC50 < 30 μM. The 3,4-dichlorocinnamanilides exhibited a broader range of activity compared to the 4-chlorocinnamanilides. The most effective agent was (2E)-N-[3,5-bis(trifluoromethyl)phenyl]-3-(3,4-dichlorophenyl)prop-2-en-amide with IC50 = 1.6 μM.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Green & Sustainable Science & Technology
Oleksandr Kuzmenko, Roman Dychkovskyi, Mykhailo Petlovanyi, Valentyn Buketov, Natalia Howaniec, Adam Smolinski
Summary: This study considers the use of backfilling systems in mining operations to preserve the surface and fully extract rich ores. The filling of mined-out stopes with a viscous fluidal solution has been found to form an artificial strong massif and conglomerate upon contact with the ore deposit. It has also been determined that exogenous fracturing significantly affects the stability of mining chambers.
Article
Engineering, Multidisciplinary
Piotr Zawadzki, Beata Koncak, Adam Smolinski
Summary: This paper analyzes the selection of a treatment system for municipal wastewater using the DuPont Water Solutions WAVE software. The results show that the application of 2-pass membrane systems enables the reclamation of water from municipal wastewater that meets the quality requirements for electrolyzer feedstock, with a conductivity of <5 mu S/cm. Depending on the case study, water reclamation ranged from 68.8% to 84.1% with energy consumption of 606.1 - 2694 kWh/d. The results highlight the importance of using software to simulate membrane system operation for selecting the most economical and cost-effective solution.
Article
Engineering, Multidisciplinary
Tomasz Siudyga, Karolina Wojtacha-Rychter, Argyrios Anagnostopoulos, Helena Navarro, Yulong Ding, Adam Smolinski, Malgorzata Magdziarczyk, Pawel Mierczynski, Jaroslaw Polanski
Summary: Energy storing systems can increase energy efficiency by addressing the intermittency issue of the current supply and demand. Thermochemical energy storage is a highly promising technology. This study experimentally investigates inductive heating as a method to directly couple power systems with thermal energy technologies for the first time. The results demonstrate the potential of waste red mud as an inductive material and its superior performance in terms of absorption capacity and desorption enthalpy compared to iron wires. The findings offer new utilization pathways for waste red mud while promoting research in the field of inductive heating.
Article
Chemistry, Medicinal
Andrzej Bak, Violetta Kozik, Aleksandra Swietlicka, Wojciech Baran, Adam Smolinski, Andrzej Zieba
Summary: The multistep synthesis of novel bis-terephthalthioamides based on methyl esters of amino acids was proposed using conventional heating and microwave-assisted approaches. The microwave-accelerated small-scale methodology resulted in significantly reduced reaction time, energy requirements, and slightly increased reaction yields when compared to conventional heating.
Article
Green & Sustainable Science & Technology
Maksym Kononenko, Oleh Khomenko, Ivan Sadovenko, Valeriy Sobolev, Yuliya Pazynich, Adam Smolinski
Summary: This study developed analytical models for the formation parameters of crumpling zones and crushing of the rock mass around the charging cavity during explosive loading, using the theory of elasticity and the main provisions of the quasi-static-wave hypothesis. Numerical modelling using the finite element method was also conducted to determine the radii of the crumpling, intensive fragmentation, and fracturing zones based on the stress-strain state of the rock mass under explosion. Comparison between analytical and numerical modelling results showed a difference in the radii values of 4%, 8%, and 6% for defined zones, respectively. These analytical models improve the accuracy of estimating rock mass destruction parameters by explosion and enhance drilling and blasting operations in mining.
JOURNAL OF SUSTAINABLE MINING
(2023)
Review
Chemistry, Multidisciplinary
Alicja Mikolajczyk, Uladzislau Zhdan, Sylvain Antoniotti, Adam Smolinski, Karolina Jagiello, Piotr Skurski, Moussab Harb, Tomasz Puzyn, Jaroslaw Polanski
Summary: Retrosynthesis is a valuable tool for simplifying the synthesis planning of organic molecules, and computer-assisted methods have enhanced its effectiveness. With the integration of computer technologies, retrosynthesis can now include database mining, reaction prediction, machine learning, and other data science tools, enabling the consideration of inorganic compounds and nanoparticles. The development of greener and more sustainable chemistry is also supported by retrosynthesis, as it allows for the selection of environmentally friendly processes and reactants. Additionally, recent advancements in computer technologies provide a chance to accurately control green and sustainable metrics at an early stage, leading to the emergence of predictive green and sustainable methods.
Article
Thermodynamics
Adam Smolinski, Natalia Howaniec
Summary: The paper presents the results of a systematic study on the co-gasification of sewage sludge blends with biomass waste using oxygen and steam. The experiments showed that gasification of sewage sludge alone was ineffective, but co-gasification with selected biomass resulted in higher gas production and better gas composition.
Article
Energy & Fuels
Artur Wodolazski, Malgorzata Magdziarczyk, Adam Smolinski
Summary: The main purpose of this paper is to conduct a techno-economic analysis on hydrogen production from biogas through steam reforming in a pilot plant. Process flow modeling is used to estimate the costs associated with equipment purchase and operation. The pilot plant installation successfully produced significant amounts of hydrogen from biomethane, showcasing its potential as an economically viable and environmentally friendly alternative. Waste-to-hydrogen conversion holds increasing importance in the global energy economy.
Article
Environmental Sciences
Toshimi Nakajima, Mao Kuragano, Makoto Yamada, Ryo Sugimoto
Summary: This study compared the contribution of submarine groundwater discharge (SGD) to river nutrient budgets at nearshore and embayment scales, and found that SGD-derived nutrients become more important at larger spatial scales.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Fan Liu, Lei Zhang, Chongyang Zhang, Ziguang Chen, Jingguang Li
Summary: NO2 emissions from wall-mounted gas stoves used for household heating have become a significant source of indoor pollution in Chinese urban areas. The high indoor concentration of NO2 poses potential health risks to residents. It is urgently necessary to establish relevant regulations and implement emission reduction technologies to reduce NO2 emissions from wall-mounted gas stoves.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Letter
Environmental Sciences
Hans Peter H. Arp, Raoul Wolf, Sarah E. Hale, Sivani Baskaran, Juliane Gluege, Martin Scheringer, Xenia Trier, Ian T. Cousins, Harrie Timmer, Roberta Hofman-Caris, Anna Lennquist, Andre D. Bannink, Gerard J. Stroomberg, Rosa M. A. Sjerps, Rosa Montes, Rosario Rodil, Jose Benito Quintana, Daniel Zahn, Herve Gallard, Tobias Mohr, Ivo Schliebner, Michael Neumann
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Philomina Onyedikachi Peter, Binessi Edouard Ifon, Francois Nkinahamira, Kayode Hassan Lasisi, Jiangwei Li, Anyi Hu, Chang-Ping Yu
Summary: This study investigates the relationship between dissolved organic matter (DOM) and Rare Earth Elements (REEs) in sediments from Yundang Lagoon, China. The results show four distinct fluorescent components, with protein-like substances being the most prevalent. Additionally, the total fluorescence intensity and LREE concentrations exhibit a synchronized increase from Outer to Inner to Songbai Lake core sediments. The findings demonstrate a strong correlation between DOM content and pollution levels.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Surya Gupta, Pasquale Borrelli, Panos Panagos, Christine Alewell
Summary: The objective of this study is to incorporate soil hydraulic properties into the erodibility factor (K) of USLE-type models. By modifying and improving the existing equations for soil texture and permeability, the study successfully included information on saturated hydraulic conductivity (Ksat) into the calculation of K factor. Using the Random Forest machine learning algorithm, two independent K factor maps with different spatial resolutions were generated. The results show that the decrease in K factor values has a positive impact on the modeling of soil erosion rates.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Jesmin Akter, Wendy J. M. Smith, Yawen Liu, Ilho Kim, Stuart L. Simpson, Phong Thai, Asja Korajkic, Warish Ahmed
Summary: The choice of workflow in wastewater surveillance has a significant impact on SARS-CoV-2 concentrations, while having minimal effects on HF183 and no effect on HAdV 40/41 concentrations. Certain components in the workflow can be interchangeable, but factors such as buffer type, chloroform, and homogenization speed can affect the recovery of viruses and bacteria.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Yu Luo, Xueting Yang, Diwei Wang, Hongmei Xu, Hongai Zhang, Shasha Huang, Qiyuan Wang, Ningning Zhang, Junji Cao, Zhenxing Shen
Summary: Atmospheric PM2.5, which can generate reactive oxygen species (ROS), is associated with cardiorespiratory morbidity and mortality. The study found that both the mass concentration of PM2.5 and the DTT activity were higher during the heating season than during the nonheating season. Combustion sources were the primary contributors to DTT activity during the heating season, while secondary formation dominated during the nonheating season. The study also revealed that biomass burning had the highest inherent oxidation potential among all sources investigated.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Erin L. Murphy, Leah R. Gerber, Chelsea M. Rochman, Beth Polidoro
Summary: Plastic pollution has devastating consequences for marine organisms. This study uses a trait-based framework to develop a vulnerability index for marine mammals, seabirds, and sea turtles in Hawai'i. The index ranks 63 study species based on their vulnerability to macroplastic pollution, providing valuable information for species monitoring and management priorities.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Kenji Maurice, Amelia Bourceret, Sami Youssef, Stephane Boivin, Liam Laurent-Webb, Coraline Damasio, Hassan Boukcim, Marc-Andre Selosse, Marc Ducousso
Summary: Growing pressure from climate change and agricultural land use is destabilizing soil microbial community interactions. Little is known about microbial community resistance and adaptation to disturbances, hindering our understanding of recovery latency and implications for ecosystem functioning. This study found that anthropic disturbance and natural disturbance have different effects on the topology and stability of soil microbial networks.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Yunhao Li, Yali Feng, Haoran Li, Yisong Yao, Chenglong Xu, Jinrong Ju, Ruiyu Ma, Haoyu Wang, Shiwei Jiang
Summary: Deep-sea mining poses a serious threat to marine ecosystems and human health by disturbing sediment and transmitting metal ions through the food chain. This study developed a new regenerative adsorption material, OMN@SA, which effectively removes metal ions. The adsorption mechanism and performance of the material for metal ion fixation were investigated.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Antonio Medici, Margherita Lavorgna, Marina Isidori, Chiara Russo, Elena Orlo, Giovanni Luongo, Giovanni Di Fabio, Armando Zarrelli
Summary: Valsartan, a widely used antihypertensive drug, has been detected in high concentrations in surface waters due to its unchanged excretion and incomplete degradation in wastewater treatment plants. This study investigated the degradation of valsartan and identified 14 degradation byproducts. The acute and chronic toxicity of these byproducts were evaluated in key organisms in the freshwater trophic chain.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Jiang Lin, Lianbao Chi, Qing Yuan, Busu Li, Mingbao Feng
Summary: This study investigated the photodegradation behavior and product formation of two representative pharmaceuticals in simulated estuary water. The study found that the formed transformation products of these pharmaceuticals have potential toxicity on marine organisms, including oxidative stress and damage to cellular components.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Hua Fang, Dongdong Jiang, Ye He, Siyi Wu, Yuehong Li, Ziqi Zhang, Haoting Chen, Zixin Zheng, Yan Sun, Wenxiang Wang
Summary: This study revealed that exposure to lower levels of air pollutants led to decreased pregnancy rates, with PM10, NO2, SO2, and CO emerging as the four most prominent pollutants. Individuals aged 35 and above exhibited heightened susceptibility to pollutants.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Ali Shaan Manzoor Ghumman, Rashid Shamsuddin, Amin Abbasi, Mohaira Ahmad, Yoshiaki Yoshida, Abdul Sami, Hamad Almohamadi
Summary: In this study, inverse vulcanized polysulfides (IVP) were synthesized by reacting molten sulfur with 4-vinyl benzyl chloride, and then functionalized using N-methyl D-glucamine (NMDG). The functionalized IVP showed a high mercury adsorption capacity and a machine learning model was developed to predict the amount of mercury removed. Furthermore, the functionalized IVP can be regenerated and reused, providing a sustainable and cost-effective adsorbent.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Rita Bonfiglio, Renata Sisto, Stefano Casciardi, Valeria Palumbo, Maria Paola Scioli, Erica Giacobbi, Francesca Servadei, Gerry Melino, Alessandro Mauriello, Manuel Scimeca
Summary: This study investigated the presence of aluminum in human colon cancer samples and its potential association with biological processes involved in cancer progression. Aluminum was found in tumor areas of 24% of patients and was associated with epithelial to mesenchymal transition (EMT) and cell death. Additional analyses revealed higher tumor mutational burden and mutations in genes related to EMT and apoptosis in aluminum-positive colon cancers. Understanding the molecular mechanisms of aluminum toxicity may improve strategies for the management of colon cancer patients.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)