期刊
SCIENCE CHINA-LIFE SCIENCES
卷 61, 期 2, 页码 170-177出版社
SCIENCE PRESS
DOI: 10.1007/s11427-017-9163-4
关键词
epigenetics; histone mark; histone modifications; structure; plant
类别
资金
- National Key R&D Program of China [2016YFA0503200]
- National Natural Science Foundation of China [31622032]
- Chinese Academy of Sciences
In eukaryotes, epigenetic-based mechanisms are involved in almost all the important biological processes. Amongst different epigenetic regulation pathways, the dynamic covalent modifications on histones are the most extensively investigated and characterized types. The covalent modifications on histone can be read by specific protein domains and then subsequently trigger downstream signaling events. Plants generally possess epigenetic regulation systems similar to animals and fungi, but also exhibit some plant-specific features. Similar to animals and fungi, plants require distinct protein domains to specifically read modified histones in both modification-specific and sequence-specific manners. In this review, we will focus on recent progress of the structural studies on the recognition of the epigenetic marks on histones by plant reader proteins, and further summarize the general and exceptional features of plant histone mark readers.
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