Crystal structure of a TAPBPR–MHC I complex reveals the mechanism of peptide editing in antigen presentation

TAPBPR bridges UDP-glucose:glycoprotein glucosyltransferase 1 onto MHC class I to provide quality control in the antigen presentation pathway

(2017) Andreas Neerincx et al.   eLife

Proofreading of Peptide—MHC Complexes through Dynamic Multivalent Interactions

(2017) Christoph Thomas et al.   Frontiers in Immunology

Interaction of TAPBPR, a tapasin homolog, with MHC-I molecules promotes peptide editing

(2016) Giora I. Morozov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Present Yourself! By MHC Class I and MHC Class II Molecules

(2016) Kenneth L. Rock et al.   TRENDS IN IMMUNOLOGY

Molecular mechanism of peptide editing in the tapasin–MHC I complex

(2016) Olivier Fisette et al.   Scientific Reports

F pocket flexibility influences the tapasin dependence of two differentially disease-associated MHC Class I proteins

(2015) Esam T. Abualrous et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Coupling between side chain interactions and binding pocket flexibility in HLA-B*44:02 molecules investigated by molecular dynamics simulations

(2015) Katja Ostermeir et al.   MOLECULAR IMMUNOLOGY

TAPBPR alters MHC class I peptide presentation by functioning as a peptide exchange catalyst

(2015) Clemens Hermann et al.   eLife

Pathways of Antigen Processing

(2013) Janice S. Blum et al.   Annual Review of Immunology

The Binding of TAPBPR and Tapasin to MHC Class I Is Mutually Exclusive

(2013) C. Hermann et al.   JOURNAL OF IMMUNOLOGY

Tapasin-related protein TAPBPR is an additional component of the MHC class I presentation pathway

(2013) Louise H. Boyle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dipeptides promote folding and peptide binding of MHC class I molecules

(2013) S. K. Saini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal Structure of the HLA-DM–HLA-DR1 Complex Defines Mechanisms for Rapid Peptide Selection

(2012) Wouter Pos et al.   CELL

Tapasin dependence of major histocompatibility complex class I molecules correlates with their conformational flexibility

(2011) Malgorzata Anna Garstka et al.   FASEB JOURNAL

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Super-resolution biomolecular crystallography with low-resolution data

(2010) Gunnar F. Schröder et al.   NATURE

HLA-DM captures partially empty HLA-DR molecules for catalyzed removal of peptide

(2010) Anne-Kathrin Anders et al.   NATURE IMMUNOLOGY

Insights into MHC Class I Peptide Loading from the Structure of the Tapasin-ERp57 Thiol Oxidoreductase Heterodimer

(2009) Gang Dong et al.   IMMUNITY

Effect of a tapasin mutant on the assembly of the mouse MHC class I molecule H2-Kd

(2009) Laura C Simone et al.   IMMUNOLOGY AND CELL BIOLOGY

Post-processing intensity measurements at favourable dose values

(2008) Kay Diederichs et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Differential tapasin dependence of MHC class I molecules correlates with conformational changes upon peptide dissociation: A molecular dynamics simulation study

(2008) Florian Sieker et al.   MOLECULAR IMMUNOLOGY