Article
Cardiac & Cardiovascular Systems
Casey Crump, Jan Sundquist, Kristina Sundquist
Summary: This study found that preterm delivery is associated with an increased risk of stroke, which remains elevated for at least 40 years after delivery and is independent of other factors and familial influences.
Article
Cardiac & Cardiovascular Systems
Xuan Sun, Huijun Zhang, Xu Tong, Feng Gao, Yiming Deng, Gaoging Ma, Ning Ma, Dapeng Mo, Ligang Song, Lian Liu, Xiaochuan Huo, Zhongrong Miao
Summary: In patients with acute basilar artery occlusion, early neurological improvement (ENI) within 24 hours after endovascular treatment (EVT) can predict favorable outcomes at 90 days. Patients with higher NIHSS, lower white blood cell counts before surgery, without general anesthetics, and complete recanalization were more likely to achieve ENI.
JOURNAL OF THROMBOSIS AND THROMBOLYSIS
(2021)
Article
Clinical Neurology
Joonsang Yoo, Jimin Jeon, Minyoul Baik, Jinkwon Kim
Summary: Background and objective: This study aimed to investigate whether statin therapy is associated with a reduced risk of stroke in patients with moyamoya disease (MMD), a chronic and progressive cerebrovascular disease. The results showed that statin therapy was significantly associated with a reduced risk of stroke and all-cause mortality in MMD patients.
STROKE AND VASCULAR NEUROLOGY
(2023)
Article
Clinical Neurology
Jia You, Yu Guo, Ju-Jiao Kang, Hui-Fu Wang, Ming Yang, Jian-Feng Feng, Jin-Tai Yu, Wei Cheng
Summary: This study developed a novel cardiovascular disease (CVD) risk prediction model using machine learning algorithms. The model identified 10 predictors from a comprehensive range of health-related factors and achieved satisfactory discriminative performance, outperforming existing clinical models. The model can effectively predict the risk of CVD and has potential for early clinical interventions.
STROKE AND VASCULAR NEUROLOGY
(2023)
Article
Clinical Neurology
Visish M. Srinivasan, Katherine Karahalios, Vamsi P. Reddy, Lea Scherschinski, Joseph D. DiDomenico, Redi Rahmani, Joshua S. Catapano, Mohamed A. Labib, Kavelin Rumalla, Christopher S. Graffeo, Michael T. Lawton
Summary: The objective of this paper was to assess the applications of the STIO approach for cerebrovascular neurosurgery. A cohort study and systematic review were conducted, finding that the STIO approach was used in 25 cerebrovascular cases. The conclusion is that the STIO approach is a safe and effective skull base approach.
JOURNAL OF NEUROSURGERY
(2023)
Article
Clinical Neurology
Eliza Miller, Anni E. Kauko, Sarah Tom, Hannele Laivuori, Teemu A. Niiranen, Natalie Bello
Summary: The study found that adverse pregnancy outcomes are associated with an earlier onset of maternal cerebrovascular disease, especially in cases where women had more than one affected pregnancy.
Article
Clinical Neurology
Yuesong Pan, Runqi Wangqin, Hao Li, Aoming Jin, Jiejie Li, Jinxi Lin, Xia Meng, Ying Xian, Daniel T. Laskowitz, Yongjun Wang
Summary: This study found that elevated untreated baseline LDL-C level was associated with an increased short-term risk of ischemic stroke among patients with minor ischemic stroke or TIA. For patients with LDL-C >= 2.6 mmol/L, lipid-lowering treatment was associated with a significantly reduced risk of ischemic stroke at 3 months.
STROKE AND VASCULAR NEUROLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Naveed Sattar, John McMurray, Jan Boren, Araz Rawshani, Elmir Omerovic, Niklas Berg, Janita Halminen, Kristoffer Skoglund, Bjorn Eliasson, Hertzel C. Gerstein, Darren K. McGuire, Deepak Bhatt, Aidin Rawshani
Summary: The goal of this study was to analyze the trends in cardiovascular events and cardiometabolic risk factor levels in individuals with type 2 diabetes (T2D) and matched control subjects. The results showed a decreasing trend in the risk and rates of atherosclerotic complications and heart failure in individuals with T2D, although the incidence of heart failure has plateaued in recent years. Modifiable risk factors within target levels were associated with lower risks for outcomes.
Article
Clinical Neurology
Nan Wang, Xiaoqiong Wang, Jingjing Yang, Tongxin Bi, Sheng Zhang, Yinghe Xu, Gengge Wang, Yongpo Jiang
Summary: This study investigated the incidence and clinical characteristics of healthcare-associated infections in elderly patients with cerebrovascular disease in the ICU. Results showed that respiratory tract infections and Gram-negative bacteria were the main causes of HAIs, leading to higher hospitalization costs and duration for these patients.
WORLD NEUROSURGERY
(2023)
Article
Geriatrics & Gerontology
Stina Ek, Debora Rizzuto, Weili Xu, Amaia Calderon-Larranaga, Anna-Karin Welmer
Summary: Living alone, being physically inactive, and having poor self-rated health amplify the negative impact of an injurious fall on functional status. Among individuals who endure an injurious fall, the heterogeneity in long-term functional status is substantial, depending on the individuals' characteristics and behaviors.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2021)
Article
Neurosciences
Lotte Gerritsen, Emma L. Twait, Palmi Jonsson, Vilmundur Gudnason, Lenore J. Launer, Mirjam Geerlings
Summary: The study found that current depression is significantly associated with an increased risk of developing dementia, including Alzheimer's disease and non-Alzheimer's dementia. However, neither the glucocorticoid cascade nor vascular hypotheses fully explained the relationship between depression and dementia, suggesting multiple biological mechanisms may be involved.
JOURNAL OF ALZHEIMERS DISEASE
(2022)
Article
Clinical Neurology
Felipe A. A. Oliveira, Mario G. G. Dourado-Filho, Pedro A. A. Sampaio Rocha-Filho
Summary: The study aimed to assess whether migraine affects the divergence between the areas of diffusion and perfusion in ischemic stroke and the prognosis after the stroke. The results showed that there was no association between migraine and the absence or volume of the ischemic penumbra, as well as the stroke prognosis.
Article
Geriatrics & Gerontology
B. Gwen Windham, Michael E. Griswold, Radhikesh Ranadive, Kevin Sullivan, Thomas H. Mosley, Michelle M. Mielke, Clifford R. Jack, Dave Knopman, Ron Petersen, Prashanthi Vemuri
Summary: This study aimed to examine if the association between cerebral perfusion and gait speed is influenced by systolic blood pressure and age. The results showed that poorer cerebral perfusion is associated with slower gait speeds, particularly with older age, while higher perfusion can significantly attenuate age-related differences in gait speed.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Clinical Neurology
Shima Shahjouei, Georgios Tsivgoulis, Ghasem Farahmand, Eric Koza, Ashkan Mowla, Alireza Vafaei Sadr, Arash Kia, Alaleh Vaghefi Far, Stefania Mondello, Achille Cernigliaro, Annemarei Ranta, Martin Punter, Faezeh Khodadadi, Soheil Naderi, Mirna Sabra, Mahtab Ramezani, Ali Amini Harandi, Oluwaseyi Olulana, Durgesh Chaudhary, Aicha Lyoubi, Bruce C. Campbell, Juan F. Arenillas, Daniel Bock, Joan Montaner, Saeideh Aghayari Sheikh Neshin, Diana Aguiar de Sousa, Matthew S. Tenser, Ana Aires, Mercedes de Lera Alfonso, Orkhan Alizada, Elsa Azevedo, Nitin Goyal, Zabihollah Babaeepour, Gelareh Banihashemi, Leo H. Bonati, Carlo W. Cereda, Jason J. Chang, Miljenko Crnjakovic, Gian Marco De Marchis, Massimo Del Sette, Seyed Amir Ebrahimzadeh, Mehdi Farhoudi, Ilaria Gandoglia, Bruno Goncalves, Christoph J. Griessenauer, Mehmet Murat Hanci, Aristeidis H. Katsanos, Christos Krogias, Ronen R. Leker, Lev Lotman, Jeffrey Mai, Shailesh Male, Konark Malhotra, Branko Malojcic, Teresa Mesquita, Asadollah Mir Ghasemi, Hany Mohamed Aref, Zeinab Mohseni Afshar, Jusun Moon, Mika Niemela, Behnam Rezai Jahromi, Lawrence Nolan, Abhi Pandhi, Jong-Ho Park, Joao Pedro Marto, Francisco Purroy, Sakineh Ranji-Burachaloo, Nuno Reis Carreira, Manuel Requena, Marta Rubiera, Seyed Aidin Sajedi, Joao Sargento-Freitas, Vijay K. Sharma, Thorsten Steiner, Kristi Tempro, Guillaume Turc, Yasaman Ahmadzadeh, Mostafa Almasi-Dooghaee, Farhad Assarzadegan, Arefeh Babazadeh, Humain Baharvandat, Fabricio Buchadid Cardoso, Apoorva Dev, Mohammad Ghorbani, Ava Hamidi, Zeynab Sadat Hasheminejad, Sahar Hojjat-Anasri Komachali, Fariborz Khorvash, Firas Kobeissy, Hamidreza Mirkarimi, Elahe Mohammadi-Vosough, Debdipto Misra, Ali Reza Noorian, Peyman Nowrouzi-Sohrabi, Sepideh Paybast, Leila Poorsaadat, Mehrdad Roozbeh, Behnam Sabayan, Saeideh Salehizadeh, Alia Saberi, Mercedeh Sepehrnia, Fahimeh Vahabizad, Thomas Alexandre Yasuda, Mojdeh Ghabaee, Nasrin Rahimian, Mohammad Hossein Harirchian, Afshin Borhani-Haghighi, Mahmoud Reza Azarpazhooh, Rohan Arora, Saeed Ansari, Venkatesh Avula, Jiang Li, Vida Abedi, Ramin Zand
Summary: This multinational observational study found that SARS-CoV-2 infected patients had a higher rate of acute ischemic stroke, intracranial hemorrhage, and cerebral venous or sinus thrombosis. Compared to pre-pandemic population studies, these patients also had a significantly higher rate of large vessel occlusions, lower rate of small vessel occlusion, and lacunar infarction, as well as a considerable number of young stroke patients. Additionally, countries with lower health expenditures had a significantly lower rate of mechanical thrombectomy.
Article
Radiology, Nuclear Medicine & Medical Imaging
Wenjin Liu, Xiaoqin Huang, Xuebing Liu, Dakota Ortega, Li Chen, Zhensen Chen, Jie Sun, Lulu Wang, Thomas S. Hatsukami, Chun Yuan, Haige Li, Junwei Yang
Summary: The study found that uncontrolled hypertension is associated with subclinical cerebrovascular injury, affecting both small and medium-to-large arteries. The presence of intracranial plaque, vascular rarefaction, reduced cerebral blood flow, and increased white matter hyperintensity were all correlated with uncontrolled hypertension, particularly with uncontrolled diastolic blood pressure.
EUROPEAN RADIOLOGY
(2021)
Article
Health Care Sciences & Services
Josefine Persson, Lars-Ake Levin, Lukas Holmegaard, Petra Redfors, Katarina Jood, Christina Jern, Christian Blomstrand, Gunilla Forsberg-Warleby
HEALTH AND QUALITY OF LIFE OUTCOMES
(2017)
Article
Rehabilitation
Tamar Abzhandadze, Gunilla Forsberg-Warleby, Lukas Holmegaard, Petra Redfors, Christina Jern, Christian Blomstrand, Katarina Jood
JOURNAL OF REHABILITATION MEDICINE
(2017)
Article
Health Care Sciences & Services
Josefine Persson, Mattias Aronsson, Lukas Holmegaard, Petra Redfors, Kaj Stenlof, Katarina Jood, Christina Jern, Christian Blomstrand, Gunilla Forsberg-Warleby, Lars-Ake Levin
QUALITY OF LIFE RESEARCH
(2017)
Article
Behavioral Sciences
Josefine Persson, Lars-Ake Levin, Lukas Holmegaard, Petra Redfors, Mikael Svensson, Katarina Jood, Christina Jern, Christian Blomstrand, Gunilla Forsberg-Warleby
BRAIN AND BEHAVIOR
(2017)
Article
Clinical Neurology
Lukas Holmegaard, Christer Jensen, Petra Redfors, Christian Blomstrand, Christina Jern, Katarina Jood
ACTA NEUROLOGICA SCANDINAVICA
(2018)
Article
Multidisciplinary Sciences
Charlotte Blomgren, Hans Samuelssonm, Christian Blomstrand, Christina Jern, Katarina Jood, Lisbeth Claesson
Article
Behavioral Sciences
Carina U. Persson, Lukas Holmegaard, Petra Redfors, Christina Jern, Christian Blomstrand, Katarina Jood
BRAIN AND BEHAVIOR
(2020)
Article
Clinical Neurology
Lukas Holmegaard, Tara M. Stanne, Ulf Andreasson, Henrik Zetterberg, Kaj Blennow, Christian Blomstrand, Katarina Jood, Christina Jern
Summary: The study found distinct protein signatures in the plasma of patients with cryptogenic stroke and LAA stroke, with RANTES, IL-4, and IFN-gamma contributing the most significantly in both subtypes. Additionally, eotaxin and MCP-1 may serve as markers of occult atherosclerosis in cryptogenic stroke.
ACTA NEUROLOGICA SCANDINAVICA
(2021)
Article
Rehabilitation
Charlotte Wassenius, Lisbeth Claesson, Christian Blomstrand, Katarina Jood, Gunnel Carlsson
Summary: This study explores the experiences of stroke survivors in terms of occupational engagement and how it evolves over time and across contexts. The results indicate that occupational engagement plays a significant role in integrating the consequences of stroke into everyday life.
SCANDINAVIAN JOURNAL OF OCCUPATIONAL THERAPY
(2022)
Article
Clinical Neurology
Annie Pedersen, Emelie Almkvist, Lukas Holmegaard, Cecilia Lagging, Petra Redfors, Christian Blomstrand, Katarina Jood, Hans Samuelsson, Christina Jern
Summary: This study found that post-stroke fatigue (PSF) is common in the long term after ischemic stroke and has a complex interplay with sex and several other outcomes. Future studies should focus on causal relationships and interventions towards fatigue and coexisting features.
ACTA NEUROLOGICA SCANDINAVICA
(2022)
Article
Clinical Neurology
Tara M. Stanne, Annelie Angerfors, Bjorn Andersson, Cecilia Brannmark, Lukas Holmegaard, Christina Jern
Summary: This study profiles inflammation-related plasma proteins in ischemic stroke patients and controls, finding differentially regulated proteins during the acute-phase and later time points. These proteins may be involved in the pathogenesis and inflammatory processes of stroke.
Article
Rehabilitation
Charlotte Wassenius, Lisbeth Claesson, Christian Blomstrand, Katarina Jood, Gunnel Carlsson
Summary: This study explored the experiences of work and work incapacity among long-term stroke survivors through individual semi-structured interviews. The results highlighted the impact of work on everyday life and the need for a flexible approach in supporting return to work as part of daily life after stroke.
SCANDINAVIAN JOURNAL OF OCCUPATIONAL THERAPY
(2023)
Article
Genetics & Heredity
Anne-Katrin Giese, Markus D. Schirmer, Kathleen L. Donahue, Lisa Cloonan, Robert Irie, Stefan Winzeck, Mark J. R. J. Bouts, Elissa C. McIntosh, Steven J. Mocking, Adrian V. Dalca, Ramesh Sridharan, Huichun Xu, Petrea Frid, Eva Giralt-Steinhauer, Lukas Holmegaard, Jaume Roquer, Johan Wasselius, John W. Cole, Patrick F. McArdle, Joseph P. Broderick, Jordi Jimenez-Conde, Christina Jern, Brett M. Kissela, Dawn O. Kleindorfer, Robin Lemmens, Arne Lindgren, James F. Meschia, Tatjana Rundek, Ralph L. Sacco, Reinhold Schmidt, Pankaj Sharma, Agnieszka Slowik, Vincent Thijs, Daniel Woo, Bradford B. Worrall, Steven J. Kittner, Braxton D. Mitchell, Jonathan Rosand, Polina Golland, Ona Wu, Natalia S. Rost
NEUROLOGY-GENETICS
(2017)