Mutational landscape of RNA-binding proteins in human cancers

Seten: a tool for systematic identification and comparison of processes, phenotypes, and diseases associated with RNA-binding proteins from condition-specific CLIP-seq profiles

(2017) Gungor Budak et al.   RNA

The distribution and mutagenesis of short coding INDELs from 1,128 whole exomes

(2015) Danny Challis et al.   BMC GENOMICS

The human RBPome: From genes and proteins to human disease

(2015) Yaseswini Neelamraju et al.   Journal of Proteomics

Ensembl 2016

(2015) Andrew Yates et al.   NUCLEIC ACIDS RESEARCH

Predictive genomics: A cancer hallmark network framework for predicting tumor clinical phenotypes using genome sequencing data

(2015) Edwin Wang et al.   SEMINARS IN CANCER BIOLOGY

Database of RNA binding protein expression and disease dynamics (READ DB)

(2015) Seyedsasan Hashemikhabir et al.   Database-The Journal of Biological Databases and Curation

Silent Mutations Make Some Noise

(2014) Siyuan Zheng et al.   CELL

SF3B1mutations constitute a novel therapeutic target in breast cancer

(2014) Sarah L Maguire et al.   JOURNAL OF PATHOLOGY

Pan-cancer network analysis identifies combinations of rare somatic mutations across pathways and protein complexes

(2014) Mark D M Leiserson et al.   NATURE GENETICS

A census of human RNA-binding proteins

(2014) Stefanie Gerstberger et al.   NATURE REVIEWS GENETICS

Ahnak functions as a tumor suppressor via modulation of TGFβ/Smad signaling pathway

(2014) I H Lee et al.   ONCOGENE

Potential predictive plasma biomarkers for cervical cancer by 2D-DIGE proteomics and Ingenuity Pathway Analysis

(2014) Xia Guo et al.   TUMOR BIOLOGY

Dissecting the expression landscape of RNA-binding proteins in human cancers

(2014) Bobak Kechavarzi et al.   GENOME BIOLOGY

Patterns of missplicing due to somatic U2AF1 mutations in myeloid neoplasms

(2013) B. Przychodzen et al.   BLOOD

RNA-binding protein PCBP2 modulates glioma growth by regulating FHL3

(2013) Wei Han et al.   JOURNAL OF CLINICAL INVESTIGATION

RBM5, 6, and 10 Differentially Regulate NUMB Alternative Splicing to Control Cancer Cell Proliferation

(2013) Elias G. Bechara et al.   MOLECULAR CELL

A compendium of RNA-binding motifs for decoding gene regulation

(2013) Debashish Ray et al.   NATURE

Mutational landscape and significance across 12 major cancer types

(2013) Cyriac Kandoth et al.   NATURE

Evidence for APOBEC3B mutagenesis in multiple human cancers

(2013) Michael B Burns et al.   NATURE GENETICS

IntOGen-mutations identifies cancer drivers across tumor types

(2013) Abel Gonzalez-Perez et al.   NATURE METHODS

Argonaute proteins: functional insights and emerging roles

(2013) Gunter Meister   NATURE REVIEWS GENETICS

The RNA-binding protein repertoire of embryonic stem cells

(2013) S Chul Kwon et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

Cancer systems biology in the genome sequencing era: Part 1, dissecting and modeling of tumor clones and their networks

(2013) Edwin Wang et al.   SEMINARS IN CANCER BIOLOGY

Cancer systems biology in the genome sequencing era: Part 2, evolutionary dynamics of tumor clonal networks and drug resistance

(2013) Edwin Wang et al.   SEMINARS IN CANCER BIOLOGY

RNA-binding proteins in Mendelian disease

(2013) Alfredo Castello et al.   TRENDS IN GENETICS

SF3B1 Mutations Are Associated with Alternative Splicing in Uveal Melanoma

(2013) S. J. Furney et al.   Cancer Discovery

The mutational landscape of chromatin regulatory factors across 4,623 tumor samples

(2013) Abel Gonzalez-Perez et al.   GENOME BIOLOGY

From specific to global analysis of posttranscriptional regulation in eukaryotes: posttranscriptional regulatory networks

(2012) S. C. Janga   Briefings in Functional Genomics

Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins

(2012) Alfredo Castello et al.   CELL

Versatility of RNA-Binding Proteins in Cancer

(2012) Laurence Wurth   COMPARATIVE AND FUNCTIONAL GENOMICS

The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts

(2012) Alexander G. Baltz et al.   MOLECULAR CELL

Functional impact bias reveals cancer drivers

(2012) Abel Gonzalez-Perez et al.   NUCLEIC ACIDS RESEARCH

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Emerging roles of RNA and RNA-binding protein network in cancer cells

(2011) Mee-Young Kim et al.   BMB Reports

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies

(2011) Brian D. Lehmann et al.   JOURNAL OF CLINICAL INVESTIGATION

Plectin promotes migration and invasion of cancer cells and is a novel prognostic marker for head and neck squamous cell carcinoma

(2011) Koji Katada et al.   Journal of Proteomics

Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes

(2011) Timothy A Graubert et al.   NATURE GENETICS

Predicting the functional impact of protein mutations: application to cancer genomics

(2011) Boris Reva et al.   NUCLEIC ACIDS RESEARCH

SLUG/SNAI2 and Tumor Necrosis Factor Generate Breast Cells With CD44+/CD24- Phenotype

(2010) Poornima Bhat-Nakshatri et al.   BMC CANCER

Pseudopodial Actin Dynamics Control Epithelial-Mesenchymal Transition in Metastatic Cancer Cells

(2010) Jay Shankar et al.   CANCER RESEARCH

Plectin-1 as a Novel Biomarker for Pancreatic Cancer

(2010) D. Bausch et al.   CLINICAL CANCER RESEARCH

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

RBPDB: a database of RNA-binding specificities

(2010) K. B. Cook et al.   NUCLEIC ACIDS RESEARCH

Reactome: a database of reactions, pathways and biological processes

(2010) D. Croft et al.   NUCLEIC ACIDS RESEARCH

A human functional protein interaction network and its application to cancer data analysis

(2010) Guanming Wu et al.   GENOME BIOLOGY

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

(2009) Gabriela Bindea et al.   BIOINFORMATICS

Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

(2009) Prateek Kumar et al.   Nature Protocols

Dissecting the expression dynamics of RNA-binding proteins in posttranscriptional regulatory networks

(2009) N. Mittal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA-binding proteins and post-transcriptional gene regulation

(2008) Tina Glisovic et al.   FEBS LETTERS

Expression patterns of epiplakin1 in pancreas, pancreatic cancer and regenerating pancreas

(2008) Tetsu Yoshida et al.   GENES TO CELLS

Neural RNA-binding protein Musashi1 inhibits translation initiation by competing with eIF4G for PABP

(2008) Hironori Kawahara et al.   JOURNAL OF CELL BIOLOGY

RNA-binding proteins in human genetic disease

(2008) Kiven E. Lukong et al.   TRENDS IN GENETICS