期刊
RNA BIOLOGY
卷 14, 期 12, 页码 1672-1677出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/15476286.2017.1356565
关键词
alpha-proteobacteria; rhizobia; riboregulation; sRNA; RNA-binding proteins
资金
- Spanish Ministerio de Economia y Competitividad ERDF [BFU2013-48282-C2-2-P]
- program of Formacion Post-doctoral from Spanish Ministerio de Economia y Competitividad
Extensive work in model enterobacteria has evidenced that the RNA chaperone Hfq and several endoribonucleases, such as RNase E or RNase III, serve pivotal roles in small RNA-mediated post-transcriptional silencing of gene expression. Characterization of these protein hubs commonly provide global functional and mechanistic insights into complex sRNA regulatory networks. The legume endosymbiont Sinorhizobium meliloti is a non-classical model bacterium with a very complex lifestyle in which riboregulation is expected to play important adaptive functions. Here, we discuss current knowledge about RNA silencing in S. meliloti from the perspective of the activity of Hfq and a recently discovered endoribonuclease (YbeY) exhibiting unprecedented catalytic versatility for the cleavage of single- and double-stranded RNA molecules.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据