Synthesis and biological evaluation of new 2-aryl-4-((4-aryl-1H-1,2,3-triazol-1-yl)methyl)thiazole derivatives

Synthesis and antimycobacterial screening of new thiazolyl-oxazole derivatives

(2017) Yogita K. Abhale et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Engineering another class of anti-tubercular lead: Hit to lead optimization of an intriguing class of gyrase ATPase inhibitors

(2016) Variam Ullas Jeankumar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Repurposing of a drug scaffold: Identification of novel sila analogues of rimonabant as potent antitubercular agents

(2016) Remya Ramesh et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Antimicrobial Screening of 2-Aryl-5-((2-arylthiazol-4-yl)methyl)-1,3,4-oxadiazole Derivatives

(2016) Pravin C. Mhaske et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Synthesis and biological screening of 2′-aryl/benzyl-2-aryl-4-methyl-4′,5-bithiazolyls as possible anti-tubercular and antimicrobial agents

(2015) Yogita K. Abhale et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Chemical and biological metal nanoparticles as antimycobacterial agents: A comparative study

(2015) Richa Singh et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Fused Heterocycles: Synthesis and Antitubercular Activity of Novel 6-Substituted-2-(4-methyl-2-substituted phenylthiazol-5-yl)H-imidazo[1,2-a]pyridine

(2015) Yogita K. Abhale et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Discovery of 4,5,6,7-Tetrahydrobenzo[1,2-d]thiazoles as Novel DNA Gyrase Inhibitors Targeting the ATP-Binding Site

(2015) Tihomir Tomašič et al.   JOURNAL OF MEDICINAL CHEMISTRY

1,2,3-Triazole derivatives as antitubercular agents: synthesis, biological evaluation and molecular docking study

(2015) Mubarak H. Shaikh et al.   MedChemComm

Identification of a new selective dopamine D4 receptor ligand

(2014) Dinithia Sampson et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Discovery of Novel 2-((Pyridin-3-yloxy)methyl)piperazines as α7 Nicotinic Acetylcholine Receptor Modulators for the Treatment of Inflammatory Disorders

(2014) Roger B. Clark et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and antiproliferative activity of conformationally restricted 1,2,3-triazole analogues of combretastatins in the sea urchin embryo model and against human cancer cell lines

(2013) Dmitry V. Demchuk et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and Inhibition Effects on 5-HT6Receptor of Benzothiazole Derivatives

(2013) Faisal Hayat et al.   BULLETIN OF THE KOREAN CHEMICAL SOCIETY

New insight into adenosine receptors selectivity derived from a novel series of [5-substituted-4-phenyl-1,3-thiazol-2-yl] benzamides and furamides

(2013) Gajanan S. Inamdar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis and anticonvulsant evaluation of N-(benzo[d]thiazol-2-ylcarbamoyl)-2-methyl-4-oxoquinazoline-3(4H)-carbothioamide derivatives: A hybrid pharmacophore approach

(2013) Sachin Malik et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Regioselective synthesis of novel 3-allyl-2-(substituted imino)-4-phenyl-3H-thiazole and 2,2′-(1,3-phenylene)bis(3-substituted-2-imino-4-phenyl-3H-thiazole) derivatives as antibacterial agents

(2013) Jafar Abbasi Shiran et al.   JOURNAL OF MOLECULAR STRUCTURE

Abyssomicins from the South China Sea Deep-Sea SedimentVerrucosisporasp.: Natural Thioether Michael Addition Adducts as Antitubercular Prodrugs

(2012) Qian Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and structure–activity relationships of tri-substituted thiazoles as RAGE antagonists for the treatment of Alzheimer’s disease

(2012) Yun Suk Lee et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Structure-Based Discovery of Substituted 4,5′-Bithiazoles as Novel DNA Gyrase Inhibitors

(2012) Matjaž Brvar et al.   JOURNAL OF MEDICINAL CHEMISTRY

Design, Synthesis, and Structure–Activity Correlations of Novel Dibenzo[b,d]furan, Dibenzo[b,d]thiophene, and N-Methylcarbazole Clubbed 1,2,3-Triazoles as Potent Inhibitors of Mycobacterium tuberculosis

(2012) Santhosh Reddy Patpi et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Antimicrobial Activities of Novel Series of 1-((4-Methyl-2-Substituted Thiazol-5-yl)Methyleneam INO)-2-Substituted Isothiourea Derivatives

(2012) Shivaji H. Shelke et al.   PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS

Synthesis and biological evaluation of some novel triazol-3-ones as antimicrobial agents

(2011) Santosh Pardeshi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Efficient synthesis and in vitro antitubercular activity of 1,2,3-triazoles as inhibitors of Mycobacterium tuberculosis

(2011) Poovan Shanmugavelan et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and biological activities of triazole derivatives as inhibitors of InhA and antituberculosis agents

(2011) Christophe Menendez et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Novel 1,2,3-Triazole Derivatives for Use againstMycobacterium tuberculosisH37Rv (ATCC 27294) Strain

(2011) Nubia Boechat et al.   JOURNAL OF MEDICINAL CHEMISTRY

Targeting tuberculosis through a small focused library of 1,2,3-triazoles

(2011) Guillermo R. Labadie et al.   MOLECULAR DIVERSITY

Pharmacological evaluation and characterizations of newly synthesized 1,2,4-triazoles

(2010) Navin B. Patel et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Triazole-Linked Inhibitors of Inosine Monophosphate Dehydrogenase from Human andMycobacterium tuberculosis

(2010) Liqiang Chen et al.   JOURNAL OF MEDICINAL CHEMISTRY

A novel screening method based on menadione mediated rapid reduction of tetrazolium salt for testing of anti-mycobacterial agents

(2010) Upasana Singh et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Design, synthesis and biological evaluation of novel triazole, urea and thiourea derivatives of quinoline against Mycobacterium tuberculosis

(2009) Ram Shankar Upadhayaya et al.   BIOORGANIC & MEDICINAL CHEMISTRY

The use of oxadiazole and triazole substituted naphthyridines as HIV-1 integrase inhibitors. Part 1: Establishing the pharmacophore

(2009) Brian A. Johns et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and anticancer activity of novel 3,4-diarylthiazol-2(3H)-ones (imines)

(2009) Zong-Ying Liu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and biological evaluation of new enantiomerically pure azole derivatives as inhibitors of Mycobacterium tuberculosis

(2009) Daniele Castagnolo et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Identification of a Metabolically Stable Triazolopyrimidine-Based Dihydroorotate Dehydrogenase Inhibitor with Antimalarial Activity in Mice

(2009) Ramesh Gujjar et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and evaluation of analgesic, anti-inflammatory and ulcerogenic activities of some triazolo- and 2-pyrazolyl-pyrido[2,3-d]-pyrimidines

(2008) Hend Hafez et al.   ACTA PHARMACEUTICA

Design and synthesis of some thiazolyl and thiadiazolyl derivatives of antipyrine as potential non-acidic anti-inflammatory, analgesic and antimicrobial agents

(2008) Sherif A.F. Rostom et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Clubbed [1,2,3] triazoles by fluorine benzimidazole: A novel approach to H37Rv inhibitors as a potential treatment for tuberculosis

(2008) Charansingh Gill et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

SAR study of clubbed [1,2,4]-triazolyl with fluorobenzimidazoles as antimicrobial and antituberculosis agents

(2008) Ganesh Rajaram Jadhav et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Bactericidal activity of 2-nitroimidazole against the active replicating stage of Mycobacterium bovis BCG and Mycobacterium tuberculosis with intracellular efficacy in THP-1 macrophages

(2008) Arshad Khan et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

A simple whole cell based high throughput screening protocol using Mycobacterium bovis BCG for inhibitors against dormant and active tubercle bacilli

(2008) Arshad Khan et al.   JOURNAL OF MICROBIOLOGICAL METHODS