Article
Nutrition & Dietetics
Jiyoung Hwang, Dayeon Shin, Hyesook Kim, Oran Kwon
Summary: This study found that among pregnant Korean women, adherence to a dietary pattern characterized by high intakes of grains, vegetables, meat, and fish is associated with a lower risk of delivering small-for-gestational-age infants.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Public, Environmental & Occupational Health
Samantha M. Lee, Ruth Mitchell, Julia A. Knight, Tony Mazzulli, Caroline Relton, Elham Khodayari Moez, Rayjean J. Hung
Summary: This study found that early childhood CMV infection was associated with suboptimal total IQ at 8 years, but not at 15 years. Additionally, suboptimal attentional control at 8 years and reading comprehension at 9 years were also linked to CMV infection. Other cognitive measures assessed did not show association with CMV infection.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2021)
Article
Environmental Sciences
Midori Yamamoto, Akifumi Eguchi, Kenichi Sakurai, Shoji F. Nakayama, Makiko Sekiyama, Chisato Mori, Michihiro Kamijima
Summary: This study investigated the association between maternal and cord blood manganese levels and neurodevelopment in children. The results showed that both maternal and cord blood manganese levels were negatively associated with neurodevelopment in children up to 3 years of age, suggesting that excessive exposure to manganese during pregnancy may have adverse effects on neuromotor function in children.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Medicine, General & Internal
Camilla Fontana, Federica Marasca, Livia Provitera, Sara Mancinelli, Nicola Pesenti, Shruti Sinha, Sofia Passera, Sergio Abrignani, Fabio Mosca, Simona Lodato, Beatrice Bodega, Monica Fumagalli
Summary: Premature infants show hypomethylation of L1 promoter at birth, and an early intervention program can restore normal methylation levels and improve neurodevelopment in children. Mouse study suggests fine-tuning of L1 activity in perinatal brain, indicating a sensitive and vulnerable window for L1 epigenetic setting.
Article
Environmental Sciences
Chaochen Ma, Miyuki Iwai-Shimada, Shoji F. Nakayama, Tomohiko Isobe, Yayoi Kobayashi, Nozomi Tatsuta, Yu Taniguchi, Makiko Sekiyama, Takehiro Michikawa, Shin Yamazaki, Michihiro Kamijima
Summary: Prenatal cadmium exposure was negatively associated with neurodevelopment in boys, in children whose mothers smoked, and in children born to mothers with gestational diabetes. Further studies in other populations are needed to confirm our findings.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Environmental Sciences
Ines Amine, Alicia Guillien, Claire Philippat, Augusto Anguita-Ruiz, Maribel Casas, Montserrat de Castro, Audrius Dedele, Judith Garcia-Aymerich, Berit Granum, Regina Grazuleviciene, Barbara Heude, Line Smastuen Haug, Jordi Julvez, Monica Lopez-Vicente, Lea Maitre, Rosemary McEachan, Mark Nieuwenhuijsen, Nikos Stratakis, Marina Vafeiadi, John Wright, Tiffany Yang, Wen Lun Yuan, Xavier Basagana, Remy Slama, Martine Vrijheid, Valerie Siroux
Summary: This study aimed to identify a childhood general health score and assess its association with a wide range of pre- and post-natal environmental exposures. The results showed that prenatal exposure to a bluespace near residency and postnatal exposures to pets, high intakes of vegetables and more physical activity were associated with a higher child's general health score. On the other hand, prenatal and postnatal exposure to tobacco, indoor air pollutants, high intake of caffeinated drinks, and few contacts with friends and family were associated with a lower general health score.
ENVIRONMENTAL HEALTH
(2023)
Article
Neurosciences
Laura A. Beggan, Maria S. Mulhern, Hanne K. Maehre, Emeir M. Mcsorley, Alison J. Yeates, Alexis Zavez, Sally W. Thurston, Conrad Shamlaye, Edwin van Wijngaarden, Philip W. Davidson, Gary J. Myers, J. J. Strain, Edel O. Elvevoll
Summary: This study investigated the association between taurine concentrations and birth anthropometric measures and cognitive development in a high fish consuming population. The results showed no significant associations between taurine concentrations and these outcomes.
Article
Psychology, Clinical
Josephine Power, Stuart Watson, Wai Chen, Andrew Lewis, Marinus van IJzendoorn, Megan Galbally
Summary: This study finds that increasing maternal depressive symptoms during the perinatal period are associated with poorer executive function outcomes in children at the age of 4, independent of prenatal smoking, drinking, or antidepressant use. The chronicity, severity, and postpartum influences of depression may play crucial roles in determining childhood executive function outcomes.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Nutrition & Dietetics
Aya Hisada, Rieko Takatani, Midori Yamamoto, Hiroko Nakaoka, Kenichi Sakurai, Chisato Mori
Summary: Inadequate maternal iodine intake during pregnancy may have negative effects on fetal brain development and neurodevelopment in offspring. Lower iodine intake is associated with an increased risk of delayed fine motor and problem-solving abilities in children at 1 and 3 years old.
Article
Cardiac & Cardiovascular Systems
Carolina C. V. Silva, Susana Santos, Ryan L. Muetzel, Meike W. Vernooij, Bas B. van Rijn, Vincent W. V. Jaddoe, Hanan El Marroun
Summary: The study found that poor maternal cardiovascular health during pregnancy may impact offspring brain development in the long term, with higher maternal diastolic blood pressure in early pregnancy associated with lower offspring white matter mean diffusivity.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Psychiatry
Daphna G. Dollberg, Keren Hanetz-Gamliel
Summary: Research suggests that adverse childhood experiences (ACEs) are a risk factor for various affective disorders and are associated with parents' difficulty in regulating emotions and hyperarousal. Maternal mentalization can moderate these links and help parents regulate their arousal and protect children. During COVID-19, we examined the mediated links between ACEs and mothers' and children's psychopathology symptoms and found that maternal mentalization and the child's age play a moderating role in these links.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Public, Environmental & Occupational Health
Meghan Smith, Alexandra Leader, Wanny Roa, Ericka Jaramillo, Davina Lazala, Jose Flores, Claudia Cadet, Turaj Vazifedan, Suzanne Bentley, Lloyd Jensen
Summary: The HMS program aims to improve maternal health outcomes in the Dominican Republic by enhancing the knowledge levels of healthcare workers through training. Following the implementation of two HMS curricula (BAB and PE&E), there was a significant improvement in average knowledge score of healthcare workers, indicating that simulation-based training has a positive impact on knowledge acquisition and skills enhancement.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Nutrition & Dietetics
Josue Cruz-Rodriguez, Andres Diaz-Lopez, Josefa Canals-Sans, Victoria Arija
Summary: This prospective cohort study examined the association between maternal vitamin B12 status and neurodevelopmental outcomes of infants at 40 days postpartum. The study found that medium maternal vitamin B12 levels in the first trimester were associated with better motor, language, and cognitive skills in infants.
Review
Psychiatry
Janna McLellan, Danielle H. J. Kim, Matthew Bruce, Alexandra Ramirez-Celis, Judy van de Water
Summary: Autism spectrum disorder (ASD) is a neurodevelopmental disorder with multiple etiologies. Maternal immune system dysregulation is a prominent risk factor, and there is emerging evidence for its role as a potential biomarker and pathologically relevant mechanism for ASD development.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Multidisciplinary Sciences
Jeongok Park, Soo Yeon Kim, Kyoungjin Lee
Summary: This systematic review and meta-analysis examined the effectiveness of behavioral sleep interventions (BSIs) on child sleep problems, maternal sleep quality, and depression. The findings showed that BSI significantly reduced child sleep problems and improved maternal sleep quality in the intervention group. However, there were no significant differences in the number of child night awakenings and maternal depression between the intervention and control groups. Further research, including more randomized controlled trials, is needed to explore the effects of BSI taking into account factors such as children's age, intervention duration, and outcome measurement time points.
SCIENTIFIC REPORTS
(2022)
Article
Public, Environmental & Occupational Health
Yoonhee Shin, Eun Jeong Choi, Bomi Park, Hye Ah Lee, Eun-Kyung Lee, Hyesook Park
Summary: This study investigates the assumption of independent occurrence of diseases in the current multimorbidity correction method used in Global Burden of Disease studies. The study compares multimorbidity-adjusted years of lived with disability (YLD) calculated using actual data and Monte-Carlo simulations. The results show that there are no significant differences between the two methods for individuals over the age of 30, but caution is needed when applying the method to individuals under 30 years old.
JOURNAL OF PREVENTIVE MEDICINE & PUBLIC HEALTH
(2022)
Article
Environmental Sciences
Jiyoung Shin, Hyesook Park, Hae Soon Kim, Eui-Jung Kim, Kyoung-Nam Kim, Yun-Chul Hong, Mina Ha, Yangho Kim, Eunhee Ha
Summary: This study found an association between pre- and postnatal exposure to air pollutants and childhood behavior. Exposure to air pollutants during the first trimester of pregnancy and the first six months of infancy significantly affected behavioral problems in 5-year-old children, with boys being more vulnerable than girls.
ENVIRONMENTAL RESEARCH
(2022)
Article
Nutrition & Dietetics
Ui-Jeong Kim, Eun-Jeong Choi, Hyunjin Park, Hye-Ah Lee, Bomi Park, Haesoon Kim, Youngsun Hong, Seungyoun Jung, Hyesook Park
Summary: This study classified and analyzed the health-related behavior of children and adolescents, and found both direct and indirect effects of these behaviors on the risk of metabolic syndrome mediated by inflammation. The results showed a significant association between inactive lifestyle and metabolic syndrome, with interleukin-6 acting as a mediating factor. Therefore, appropriate health behavior interventions during childhood and adolescence are important for preventing metabolic syndrome.
Article
Nutrition & Dietetics
Jonghee Kim, Joanne F. Dorgan, Hyesook Kim, Oran Kwon, Yangha Kim, Yuri Kim, Kwang Suk Ko, Yoon Jung Park, Hyesook Park, Seungyoun Jung
Summary: The use of nutrition labels is associated with a lower risk of chronic kidney disease, especially in older adults.
Article
Environmental Sciences
Jaehyun Park, Woo Jin Kim, Jeeyoung Kim, Chan-Yeong Jeong, Hyesook Park, Yun-Chul Hong, Mina Ha, Yangho Kim, Sungho Won, Eunhee Ha
Summary: This study using a Korean birth cohort found that prenatal exposure to PM10 and NO2 can affect DNA methylation in the fetus, especially during midpregnancy.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Gastroenterology & Hepatology
Seung Yong Shin, Young Kim, Won-Seok Kim, Jung Min Moon, Kang-Moon Lee, Sung-Ae Jung, Hyesook Park, Eun Young Huh, Byung Chang Kim, Soo Chan Lee, Chang Hwan Choi
Summary: This study investigated the fecal microbiota profiles of Korean patients with inflammatory bowel disease (IBD) and identified bacterial biomarkers associated with disease phenotypes and prognosis. The findings may have implications for the diagnosis, prediction, and treatment of IBD.
INTESTINAL RESEARCH
(2022)
Article
Medicine, General & Internal
Hang A. Park, Federico E. Vaca, Kyunghee Jung-Choi, Hyesook Park, Ju Ok Park
Summary: Although individual socioeconomic status (SES) is difficult to modify, interventions targeting area-based SES can have an impact. In this study, we analyzed the effect of area-based SES on hospitalization for traumatic brain injury (TBI) and identified increasing inequality trends. This information can guide public health interventions.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Hyunjin Park, Seunghee Jun, Hye-Ah Lee, Hae Soon Kim, Young Sun Hong, Hyesook Park
Summary: The prevalence of obesity and metabolic syndrome (MetS) in the pediatric population has increased globally. This study evaluated the impact of childhood obesity and sarcopenic obesity on the risk of MetS in adolescence using cohort study data. Overweight and obesity were defined based on body mass index (BMI) percentiles, and sarcopenic obesity was defined using body composition data. The results showed that overweight and sarcopenic obese individuals have a higher overall risk of MetS components compared to normal people. Both overweight and sarcopenic obesity remained significantly associated with MetS indicators, even after adjusting for covariates. The study emphasizes the importance of early detection of childhood obesity and effective public health interventions.
Article
Public, Environmental & Occupational Health
Hyunjin Park, Ui-Jeong Kim, Eun Jeong Choi, Seunghee Jun, Bomi Park, Hye Ah Lee, Hae Soon Kim, Hyesook Park
Summary: This study found an association between exposure to secondhand smoke and components of metabolic syndrome (MetS) in adolescents aged 13-15 years. Specifically, higher levels of urinary cotinine, a marker of secondhand smoke exposure, were associated with lower levels of high-density lipoprotein cholesterol (HDL-C). These findings highlight the importance of addressing secondhand smoke exposure in adolescents to reduce their risk of cardiovascular disease in later life.
Article
Multidisciplinary Sciences
Jongmin Oh, Whanhee Lee, Choong-jong Kim, Yi Jun Kim, Hyesook Park, Ji Hyen Lee, Mi Hye Park, Seulbi Lee, Eunhee Ha, Kyung A. A. Lee
Summary: This study investigated the effects of COVID-19 infection on maternal and neonatal outcomes in Korea from the pre-Delta to the initial Omicron epidemic periods. The results showed that COVID-19 had little effect on maternal and neonatal outcomes, but infection in the second trimester was associated with postpartum hemorrhages, and neonatal intensive care unit admissions increased. The study suggests that the timely and successful policies of the government and academia in response to COVID-19 infections in newborns in Korea may cause an increase in NICU admissions, but simultaneously prevent adverse maternal and neonatal outcomes.
Article
Multidisciplinary Sciences
Sung Hee Lee, Eun Jeong Choi, Ui Jeong Kim, Hyunjin Park, Bomi Park, Hye Ah Lee, Hyesook Park
Summary: This study found that serum uric acid (SUA) and body mass index (BMI) trajectories in childhood are longitudinally associated with liver enzymes in adolescence. The levels of liver function enzymes such as AST, ALT, and gamma-GTP were also affected.
Article
Nutrition & Dietetics
Su Min Kim, Yoon Jung Park, Hyesook Kim, Oran Kwon, Kwang Suk Ko, Yuri Kim, Yangha Kim, Hyesook Park, Seungyoun Jung
Summary: Food insecurity may lead to poor diets and inflammation, negatively affecting skeletal muscle metabolism. In a study of Korean adults, higher food insecurity was associated with a greater inflammatory potential of diets and an increased risk of low muscle strength. This suggests that individuals with greater food insecurity may be at risk for a loss of muscle strength due to diets with higher inflammation levels.
Article
Public, Environmental & Occupational Health
Na-Young Jeong, Hyesook Park, Sanghoon Oh, Seung Eun Jung, Dong-Hyun Kim, Hyoung-Shik Shin, Hee Chul Han, Jong-Koo Lee, Jun Hee Woo, Byung-Joo Park, Nam-Kyong Choi
Summary: To assess post-vaccination adverse events, the Korea Disease Control and Prevention Agency established the COVID-19 Vaccine Safety Research Committee, which completed research on 15 adverse events using pseudonymized data. The committee also launched the COVID-19 Vaccine Safety Research Center to continue providing scientific evidence and serve as a model for future epidemics.
OSONG PUBLIC HEALTH AND RESEARCH PERSPECTIVES
(2023)
Article
Endocrinology & Metabolism
Hye Ah Lee, Hyesook Park
Summary: This study aimed to assess the effect of obesity phenotype on the incidence of diabetes. The results showed that individuals with metabolically healthy obesity had a higher risk of diabetes compared to those with metabolically healthy normal weight.
DIABETES OBESITY & METABOLISM
(2023)
Article
Pediatrics
Jung Eun Choi, Hye Ah Lee, Sung Won Park, Jung Won Lee, Ji Hyen Lee, Hyesook Park, Hae Soon Kim
Summary: This study aimed to evaluate the prevalence of obesity and metabolic syndrome among children and adolescents after the COVID-19 outbreak in Korea. The results showed that the mean body mass index (BMI) increased significantly among 2-9-year-olds, while there was a slight increase among 10-18-year-olds. The prevalence of metabolic syndrome in adolescents also increased.
