Exploring the cause of aggregation and reduced Zn binding affinity by G85R mutation in SOD1 rendering amyotrophic lateral sclerosis

Metal-deficient SOD1 in amyotrophic lateral sclerosis

(2015) James B. Hilton et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Role of mitochondria in mutant SOD1 linked amyotrophic lateral sclerosis

(2014) Wenzhi Tan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Cu,Zn-Superoxide Dismutase without Zn Is Folded but Catalytically Inactive

(2014) Sean Nedd et al.   JOURNAL OF MOLECULAR BIOLOGY

PredictSNP: Robust and Accurate Consensus Classifier for Prediction of Disease-Related Mutations

(2014) Jaroslav Bendl et al.   PLoS Computational Biology

Structures of the E46K Mutant-Type α-Synuclein Protein and Impact of E46K Mutation on the Structures of the Wild-Type α-Synuclein Protein

(2013) Olivia Wise-Scira et al.   ACS Chemical Neuroscience

Features of wild-type human SOD1 limit interactions with misfolded aggregates of mouse G86R Sod1

(2013) David A Qualls et al.   Molecular Neurodegeneration

An emerging role for misfolded wild-type SOD1 in sporadic ALS pathogenesis

(2013) Melissa S. Rotunno et al.   Frontiers in Cellular Neuroscience

Discrete Molecular Dynamics: An Efficient And Versatile Simulation Method For Fine Protein Characterization

(2012) David Shirvanyants et al.   JOURNAL OF PHYSICAL CHEMISTRY B

All-Atom Molecular Dynamics Simulations Reveal Significant Differences in Interaction between Antimycin and Conserved Amino Acid Residues in Bovine and Bacterial bc 1 Complexes

(2011) Oleksandr Kokhan et al.   BIOPHYSICAL JOURNAL

Predicting the functional impact of protein mutations: application to cancer genomics

(2011) Boris Reva et al.   NUCLEIC ACIDS RESEARCH

Aggregation of Copper–Zinc Superoxide Dismutase in Familial and Sporadic ALS

(2009) Madhuri Chattopadhyay et al.   ANTIOXIDANTS & REDOX SIGNALING

Loss of Metal Ions, Disulfide Reduction and Mutations Related to Familial ALS Promote Formation of Amyloid-Like Aggregates from Superoxide Dismutase

(2009) Zeynep A. Oztug Durer et al.   PLoS One

A Limited Role for Disulfide Cross-linking in the Aggregation of Mutant SOD1 Linked to Familial Amyotrophic Lateral Sclerosis

(2008) Celeste M. Karch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structures of the G85R Variant of SOD1 in Familial Amyotrophic Lateral Sclerosis

(2008) Xiaohang Cao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Complete Loss of Post-translational Modifications Triggers Fibrillar Aggregation of SOD1 in the Familial Form of Amyotrophic Lateral Sclerosis

(2008) Yoshiaki Furukawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GROMACS 4:  Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

(2008) Berk Hess et al.   Journal of Chemical Theory and Computation

Dynamical roles of metal ions and the disulfide bond in Cu, Zn superoxide dismutase folding and aggregation

(2008) F. Ding et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ab Initio Folding of Proteins with All-Atom Discrete Molecular Dynamics

(2008) Feng Ding et al.   STRUCTURE

Metal-Coupled Folding of Cys2His2Zinc-Finger

(2007) Wenfei Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY