4.2 Review

Dietary Additive Probiotics Modulation of the Intestinal Microbiota

期刊

PROTEIN AND PEPTIDE LETTERS
卷 24, 期 5, 页码 382-387

出版社

BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/0929866524666170223143615

关键词

Probiotics; gut; microbiota; animal; modulation; mechanism

资金

  1. National Natural Science Foundation of China [31601955, 31472112]
  2. Start-up Fund of the Natural Science Foundation of Guangdong Province [2016A030310322]
  3. Special Fund for Agro-scientific Research in the Public Interest [201403047]
  4. Science and Technology Planning Project of Guangzhou [201607020035]

向作者/读者索取更多资源

The importance of the intestinal microbiota of animals is widely acknowledged because of its vital role in the health of animals. There are complex communities of microbiota, which colonize the gastrointestinal tract. Intestinal microbiota are conductive to animal health and the development of the host immune system. Probiotics are commonly used dietary additives where they provide the host with many beneficial functions, such as modulating intestinal homeostasis and promoting gut health. These beneficial effects of probiotics may accrue from the inhibiting the growth of pathogenic bacteria and promoting the growth of beneficial flora in the gastrointestinal tract. Probiotics colonization and its impact on gut microbiota members are highly species specific. Different probiotics have been shown to have dramatically different capacities of modulation physiological function. This review summarizes existing studies of the influence of dietary additive probiotics on the gut microbiota in different animals, such as humans, mice, pigs and chickens, to clarify the contribution of different kinds of probiotics to the intestinal microbiota. Moreover, the probable mechanism for the benefits of dietary supplementation with probiotics will be discussed.

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