Selective lowering of synapsins induced by oligomeric α-synuclein exacerbates memory deficits
出版年份 2017 全文链接
标题
Selective lowering of synapsins induced by oligomeric α-synuclein exacerbates memory deficits
作者
关键词
-
出版物
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 114, Issue 23, Pages E4648-E4657
出版商
Proceedings of the National Academy of Sciences
发表日期
2017-05-23
DOI
10.1073/pnas.1704698114
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Molecular and Biological Compatibility with Host Alpha-Synuclein Influences Fibril Pathogenicity
- (2016) Kelvin C. Luk et al. Cell Reports
- Neurodegenerative Diseases: Expanding the Prion Concept
- (2015) Lary C. Walker et al. Annual Review of Neuroscience
- Pathological Interface Between Oligomeric Alpha-Synuclein and Tau in Synucleinopathies
- (2015) Urmi Sengupta et al. BIOLOGICAL PSYCHIATRY
- Nurr1 and Retinoid X Receptor Ligands Stimulate Ret Signaling in Dopamine Neurons and Can Alleviate -Synuclein Disrupted Gene Expression
- (2015) N. Volakakis et al. JOURNAL OF NEUROSCIENCE
- Definition of a Molecular Pathway Mediating -Synuclein Neurotoxicity
- (2015) J. Burre et al. JOURNAL OF NEUROSCIENCE
- α-Synuclein strains cause distinct synucleinopathies after local and systemic administration
- (2015) W. Peelaerts et al. NATURE
- Inhibition of amyloid-β plaque formation by α-synuclein
- (2015) Teresa Bachhuber et al. NATURE MEDICINE
- Parkinson-causing α-synuclein missense mutations shift native tetramers to monomers as a mechanism for disease initiation
- (2015) Ulf Dettmer et al. Nature Communications
- Quaternary Structure Defines a Large Class of Amyloid-β Oligomers Neutralized by Sequestration
- (2015) Peng Liu et al. Cell Reports
- Recurrent turnover of senescent cells during regeneration of a complex structure
- (2015) Maximina H Yun et al. eLife
- Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivo
- (2014) Edward Rockenstein et al. BRAIN
- Cell-to-cell transmission of pathogenic proteins in neurodegenerative diseases
- (2014) Jing L Guo et al. NATURE MEDICINE
- Single App knock-in mouse models of Alzheimer's disease
- (2014) Takashi Saito et al. NATURE NEUROSCIENCE
- Addition of exogenous α-synuclein preformed fibrils to primary neuronal cultures to seed recruitment of endogenous α-synuclein to Lewy body and Lewy neurite–like aggregates
- (2014) Laura A Volpicelli-Daley et al. Nature Protocols
- Brain amyloid-β oligomers in ageing and Alzheimer’s disease
- (2013) Sylvain E. Lesné et al. BRAIN
- Overview and Findings from the Religious Orders Study
- (2013) David A. Bennett et al. Current Alzheimer Research
- SYN2 is an autism predisposing gene: loss-of-function mutations alter synaptic vesicle cycling and axon outgrowth
- (2013) Anna Corradi et al. HUMAN MOLECULAR GENETICS
- In VivoCross-linking Reveals Principally Oligomeric Forms of α-Synuclein and β-Synuclein in Neurons and Non-neural Cells
- (2013) Ulf Dettmer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Properties of native brain α-synuclein
- (2013) Jacqueline Burré et al. NATURE
- Self-propagation of pathogenic protein aggregates in neurodegenerative diseases
- (2013) Mathias Jucker et al. NATURE
- NURR1 in Parkinson disease—from pathogenesis to therapeutic potential
- (2013) Mickael Decressac et al. Nature Reviews Neurology
- Defining the Native State of α-Synuclein
- (2013) Dennis Selkoe et al. Neurodegenerative Diseases
- The Function of α-Synuclein
- (2013) Jacob T. Bendor et al. NEURON
- Large -synuclein oligomers inhibit neuronal SNARE-mediated vesicle docking
- (2013) B.-K. Choi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Neurotoxicity of Amyloid -Protein: Synaptic and Network Dysfunction
- (2013) L. Mucke et al. Cold Spring Harbor Perspectives in Medicine
- Native α-synuclein induces clustering of synaptic-vesicle mimics via binding to phospholipids and synaptobrevin-2/VAMP2
- (2013) Jiajie Diao et al. eLife
- Seizures and Epileptiform Activity in the Early Stages of Alzheimer Disease
- (2013) Keith A. Vossel et al. JAMA Neurology
- The Membrane Fusion Enigma: SNAREs, Sec1/Munc18 Proteins, and Their Accomplices—Guilty as Charged?
- (2012) Josep Rizo et al. Annual Review of Cell and Developmental Biology
- Inhibitory Interneuron Deficit Links Altered Network Activity and Cognitive Dysfunction in Alzheimer Model
- (2012) Laure Verret et al. CELL
- The Amyloid State of Proteins in Human Diseases
- (2012) David Eisenberg et al. CELL
- Characterization of CpG island DNA methylation of impairment-related genes in a rat model of cognitive aging
- (2012) Rebecca Haberman et al. Epigenetics
- Specificity Protein 1 (Sp1)-dependent Activation of the Synapsin I Gene (SYN1) Is Modulated by RE1-silencing Transcription Factor (REST) and 5′-Cytosine-Phosphoguanine (CpG) Methylation
- (2012) Francesco Paonessa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- α-Synuclein in Central Nervous System and from Erythrocytes, Mammalian Cells, andEscherichia coliExists Predominantly as Disordered Monomer
- (2012) Bruno Fauvet et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice
- (2012) Kelvin C. Luk et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Soluble -Synuclein Is a Novel Modulator of Alzheimer's Disease Pathophysiology
- (2012) M. E. Larson et al. JOURNAL OF NEUROSCIENCE
- Accumulation of Toxic -Synuclein Oligomer within Endoplasmic Reticulum Occurs in -Synucleinopathy In Vivo
- (2012) E. Colla et al. JOURNAL OF NEUROSCIENCE
- The Complex PrPc-Fyn Couples Human Oligomeric A with Pathological Tau Changes in Alzheimer's Disease
- (2012) M. Larson et al. JOURNAL OF NEUROSCIENCE
- The many faces of α-synuclein: from structure and toxicity to therapeutic target
- (2012) Hilal A. Lashuel et al. NATURE REVIEWS NEUROSCIENCE
- -Synuclein-Induced Down-Regulation of Nurr1 Disrupts GDNF Signaling in Nigral Dopamine Neurons
- (2012) M. Decressac et al. Science Translational Medicine
- SYN1 loss-of-function mutations in autism and partial epilepsy cause impaired synaptic function
- (2011) Anna Fassio et al. HUMAN MOLECULAR GENETICS
- Soluble Aβ oligomer production and toxicity
- (2011) Megan E. Larson et al. JOURNAL OF NEUROCHEMISTRY
- Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice
- (2011) Cristian A Lasagna-Reeves et al. Molecular Neurodegeneration
- α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation
- (2011) Tim Bartels et al. NATURE
- In vivo demonstration that -synuclein oligomers are toxic
- (2011) B. Winner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Pathologic Cascade Leading to Synaptic Dysfunction in -Synuclein-Induced Neurodegeneration
- (2010) D. A. Scott et al. JOURNAL OF NEUROSCIENCE
- Synergistic Interactions between A , Tau, and -Synuclein: Acceleration of Neuropathology and Cognitive Decline
- (2010) L. K. Clinton et al. JOURNAL OF NEUROSCIENCE
- Increased Expression of α-Synuclein Reduces Neurotransmitter Release by Inhibiting Synaptic Vesicle Reclustering after Endocytosis
- (2010) Venu M. Nemani et al. NEURON
- Selective Disruption of the Cerebral Neocortex in Alzheimer's Disease
- (2010) Rahul S. Desikan et al. PLoS One
- The synapsins: Key actors of synapse function and plasticity
- (2010) F. Cesca et al. PROGRESS IN NEUROBIOLOGY
- -Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro
- (2010) J. Burre et al. SCIENCE
- Forebrain overexpression of α-synuclein leads to early postnatal hippocampal neuron loss and synaptic disruption
- (2009) Youngshin Lim et al. EXPERIMENTAL NEUROLOGY
- Synaptic Depression and Aberrant Excitatory Network Activity in Alzheimer’s Disease: Two Faces of the Same Coin?
- (2009) Jorge J. Palop et al. NEUROMOLECULAR MEDICINE
- Synapsin-I- and synapsin-II-null mice display an increased age-dependent cognitive impairment
- (2008) A. Corradi et al. JOURNAL OF CELL SCIENCE
- Formation of Toxic Oligomeric α-Synuclein Species in Living Cells
- (2008) Tiago Fleming Outeiro et al. PLoS One
- Mechanisms of Hybrid Oligomer Formation in the Pathogenesis of Combined Alzheimer's and Parkinson's Diseases
- (2008) Igor F. Tsigelny et al. PLoS One
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started