Unearthing a sesterterpene biosynthetic repertoire in the Brassicaceae through genome mining reveals convergent evolution

Draft Genome Sequence of Mentha longifolia and Development of Resources for Mint Cultivar Improvement

(2017) Kelly J. Vining et al.   Molecular Plant

plantiSMASH: automated identification, annotation and expression analysis of plant biosynthetic gene clusters

(2017) Satria A. Kautsar et al.   NUCLEIC ACIDS RESEARCH

(+)-Thalianatriene and (−)-Retigeranin B Catalyzed by Sesterterpene Synthases from Arabidopsis thaliana

(2017) Jie Shao et al.   ORGANIC LETTERS

Structure and Function of Fusicoccadiene Synthase, a Hexameric Bifunctional Diterpene Synthase

(2016) Mengbin Chen et al.   ACS Chemical Biology

Astellifadiene: Structure Determination by NMR Spectroscopy and Crystalline Sponge Method, and Elucidation of its Biosynthesis

(2016) Yudai Matsuda et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Genome-Based Discovery of an Unprecedented Cyclization Mode in Fungal Sesterterpenoid Biosynthesis

(2016) Masahiro Okada et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural Analyses of Short-Chain Prenyltransferases Identify an Evolutionarily Conserved GFPPS Clade in Brassicaceae Plants

(2016) Chengyuan Wang et al.   Molecular Plant

Interactive tree of life (iTOL) v3: an online tool for the display and annotation of phylogenetic and other trees

(2016) Ivica Letunic et al.   NUCLEIC ACIDS RESEARCH

Identification of a Dolabellane Type Diterpene Synthase and other Root-Expressed Diterpene Synthases in Arabidopsis

(2016) Qiang Wang et al.   Frontiers in Plant Science

An Unusual Chimeric Diterpene Synthase from Emericella variecolor and Its Functional Conversion into a Sesterterpene Synthase by Domain Swapping

(2015) Bin Qin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Molecular and functional evolution of the fungal diterpene synthase genes

(2015) Marc JC Fischer et al.   BMC MICROBIOLOGY

Genome sequencing of herb Tulsi (Ocimum tenuiflorum) unravels key genes behind its strong medicinal properties

(2015) Atul K. Upadhyay et al.   BMC PLANT BIOLOGY

Sesterterpenoids with Anticancer Activity

(2015) Antonio Evidente et al.   CURRENT MEDICINAL CHEMISTRY

Targeting cancer with sesterterpenoids: the new potential antitumor drugs

(2015) Caiguo Zhang et al.   Journal of Natural Medicines

A Century of Gibberellin Research

(2015) Peter Hedden et al.   JOURNAL OF PLANT GROWTH REGULATION

Genome Mining for Sesterterpenes Using Bifunctional Terpene Synthases Reveals a Unified Intermediate of Di/Sesterterpenes

(2015) Ying Ye et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multiple Levels of Regulation Determine Monoterpenoid Essential Oil Compositional Variation in the Mint Family

(2015) Amirhossein Ahkami et al.   Molecular Plant

The Pfam protein families database: towards a more sustainable future

(2015) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

Molecular Basis for Stellatic Acid Biosynthesis: A Genome Mining Approach for Discovery of Sesterterpene Synthases

(2015) Yudai Matsuda et al.   ORGANIC LETTERS

Arabidopsis thalianaisoprenyl diphosphate synthases produce the C25intermediate geranylfarnesyl diphosphate

(2015) Raimund Nagel et al.   PLANT JOURNAL

How cyclobutanes are assembled in nature – insights from quantum chemistry

(2014) Young J. Hong et al.   CHEMICAL SOCIETY REVIEWS

Transient expressions of synthetic biology in plants

(2014) Frank Sainsbury et al.   CURRENT OPINION IN PLANT BIOLOGY

Investigation of terpene diversification across multiple sequenced plant genomes

(2014) Alexander M. Boutanaev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sesterterpenoids

(2013) Lishu Wang et al.   NATURAL PRODUCT REPORTS

Peltate Glandular Trichomes of Colquhounia coccinea var. mollis Harbor a New Class of Defensive Sesterterpenoids

(2013) Chun-Huan Li et al.   ORGANIC LETTERS

Identification of Ophiobolin F Synthase by a Genome Mining Approach: A Sesterterpene Synthase from Aspergillus clavatus

(2013) Ryota Chiba et al.   ORGANIC LETTERS

Evolution of a Complex Locus for Terpene Biosynthesis in Solanum

(2013) Y. Matsuba et al.   PLANT CELL

Biochemical analysis of a multifunctional cytochrome P450 (CYP51) enzyme required for synthesis of antimicrobial triterpenes in plants

(2013) K. Geisler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

C–H⋯π interactions as modulators of carbocation structure – implications for terpene biosynthesis

(2013) Young J. Hong et al.   Chemical Science

Defense sesterterpenoid lactones from Leucosceptrum canum

(2012) Shi-Hong Luo et al.   PHYTOCHEMISTRY

Transcriptome mining, functional characterization, and phylogeny of a large terpene synthase gene family in spruce (Picea spp.)

(2011) Christopher I Keeling et al.   BMC PLANT BIOLOGY

Biosynthesis via carbocations: Theoretical studies on terpene formation

(2011) Dean J. Tantillo   NATURAL PRODUCT REPORTS

Defensive Sesterterpenoids with Unusual Antipodal Cyclopentenones from the Leaves ofLeucosceptrum canum

(2011) Shi-Hong Luo et al.   ORGANIC LETTERS

The Tomato Terpene Synthase Gene Family

(2011) V. Falara et al.   PLANT PHYSIOLOGY

Formation of plant metabolic gene clusters within dynamic chromosomal regions

(2011) B. Field et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Accelerated Profile HMM Searches

(2011) Sean R. Eddy   PLoS Computational Biology

Glandular Trichomes of Leucosceptrum canum Harbor Defensive Sesterterpenoids

(2010) Shi-Hong Luo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

FastTree 2 – Approximately Maximum-Likelihood Trees for Large Alignments

(2010) Morgan N. Price et al.   PLoS One

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Biosynthetic Gene-Based Secondary Metabolite Screening: A New Diterpene, Methyl Phomopsenonate, from the FungusPhomopsis amygdali

(2009) Tomonobu Toyomasu et al.   JOURNAL OF ORGANIC CHEMISTRY

pEAQ: versatile expression vectors for easy and quick transient expression of heterologous proteins in plants

(2009) Frank Sainsbury et al.   PLANT BIOTECHNOLOGY JOURNAL

Monoterpenes in the glandular trichomes of tomato are synthesized from a neryl diphosphate precursor rather than geranyl diphosphate

(2009) A. L. Schilmiller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Determination of absolute structure using Bayesian statistics on Bijvoet differences

(2008) Rob W. W. Hooft et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Functional plasticity of paralogous diterpene synthases involved in conifer defense

(2008) C. I. Keeling et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA