Structural insights into the extracellular recognition of the human serotonin 2B receptor by an antibody

Structure of the adenosine A2A receptor bound to an engineered G protein

(2016) Byron Carpenter et al.   NATURE

Successful Strategies to Determine High-Resolution Structures of GPCRs

(2016) Jin Xiang et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Structural insights into µ-opioid receptor activation

(2015) Weijiao Huang et al.   NATURE

Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser

(2015) Yanyong Kang et al.   NATURE

PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome

(2015) Wesley K Kroeze et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome

(2015) Wesley K Kroeze et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Preparation of microcrystals in lipidic cubic phase for serial femtosecond crystallography

(2014) Wei Liu et al.   Nature Protocols

Cheetah: software for high-throughput reduction and analysis of serial femtosecond X-ray diffraction data

(2014) Anton Barty et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Activation and allosteric modulation of a muscarinic acetylcholine receptor

(2013) Andrew C. Kruse et al.   NATURE

Structural Features for Functional Selectivity at Serotonin Receptors

(2013) D. Wacker et al.   SCIENCE

Serial Femtosecond Crystallography of G Protein-Coupled Receptors

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Exploiting structure similarity in refinement: automated NCS and target-structure restraints inBUSTER

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Structure-Function of the G Protein–Coupled Receptor Superfamily

(2012) Vsevolod Katritch et al.   Annual Review of Pharmacology and Toxicology

Mechanism of action of therapeutic monoclonal antibodies: Promises and pitfalls of in vitro and in vivo assays

(2012) Josée Golay et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Opportunities for functional selectivity in GPCR antibodies

(2012) David R. Webb et al.   BIOCHEMICAL PHARMACOLOGY

CrystFEL: a software suite for snapshot serial crystallography

(2012) Thomas A. White et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

PheVI:09 (Phe6.44) as a Sliding Microswitch in Seven-transmembrane (7TM) G Protein-coupled Receptor Activation

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Structure of a nanobody-stabilized active state of the β2 adrenoceptor

(2011) Søren G. F. Rasmussen et al.   NATURE

Crystal structure of the β2 adrenergic receptor–Gs protein complex

(2011) Søren G. F. Rasmussen et al.   NATURE

Structure of an Agonist-Bound Human A2A Adenosine Receptor

(2011) F. Xu et al.   SCIENCE

PHENIX: a comprehensive Python-based system for macromolecular structure solution

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Phase I Study of KW-0761, a Defucosylated Humanized Anti-CCR4 Antibody, in Relapsed Patients With Adult T-Cell Leukemia-Lymphoma and Peripheral T-Cell Lymphoma

(2010) Kazuhito Yamamoto et al.   JOURNAL OF CLINICAL ONCOLOGY

Therapeutic antibodies directed at G protein-coupled receptors

(2010) Catherine J. Hutchings et al.   mAbs

CXCR4 nanobodies (VHH-based single variable domains) potently inhibit chemotaxis and HIV-1 replication and mobilize stem cells

(2010) S. Jahnichen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystallizing membrane proteins using lipidic mesophases

(2009) Martin Caffrey et al.   Nature Protocols

Antibodies Against G-Protein Coupled Receptors: Novel Uses in Screening and Drug Development

(2008) Achla Gupta et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING