Senescent cells expose and secrete an oxidized form of membrane-bound vimentin as revealed by a natural polyreactive antibody

The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4

(2015) C. Kang et al.   SCIENCE

BubR1 kinase: protection against aneuploidy and premature aging

(2015) Maria Kapanidou et al.   TRENDS IN MOLECULAR MEDICINE

Vimentin filament organization and stress sensing depend on its single cysteine residue and zinc binding

(2015) Dolores Pérez-Sala et al.   Nature Communications

Universal Marker and Detection Tool for Human Sarcoma Circulating Tumor Cells

(2014) Arun Satelli et al.   CANCER RESEARCH

B Cells and Humoral Immunity in Atherosclerosis

(2014) Dimitrios Tsiantoulas et al.   CIRCULATION RESEARCH

Circulating Tumor Cell Enumeration with a Combination of Epithelial Cell Adhesion Molecule- and Cell-Surface Vimentin-Based Methods for Monitoring Breast Cancer Therapeutic Response

(2014) A. Satelli et al.   CLINICAL CHEMISTRY

Error-free versus mutagenic processing of genomic uracil—Relevance to cancer

(2014) Hans E. Krokan et al.   DNA REPAIR

Cell-surface Vimentin: A mislocalized protein for isolating csVimentin+CD133−novel stem-like hepatocellular carcinoma cells expressing EMT markers

(2014) Abhisek Mitra et al.   INTERNATIONAL JOURNAL OF CANCER

Natural Antibodies Bridge Innate and Adaptive Immunity

(2014) Saswati Panda et al.   JOURNAL OF IMMUNOLOGY

Circulating microparticles carry oxidation-specific epitopes and are recognized by natural IgM antibodies

(2014) Dimitrios Tsiantoulas et al.   JOURNAL OF LIPID RESEARCH

The role of senescent cells in ageing

(2014) Jan M. van Deursen   NATURE

Relationship Between Oxidized LDL, IgM, and IgG Autoantibodies to ox-LDL Levels With Recurrent Cardiovascular Events in Swedish Patients With Previous Myocardial Infarction

(2013) M. Crisby et al.   ANGIOLOGY

Age-related changes of forkhead transcription factor FOXO1 in the liver of senescence-accelerated mouse SAMP8

(2013) Koji Tomobe et al.   ARCHIVES OF GERONTOLOGY AND GERIATRICS

Possible involvement of Hcn1 ion channel in learning and memory dysfunction in SAMP8 mice

(2013) Maruf Mohammad Akbor et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Immunosurveillance of senescent cells: the bright side of the senescence program

(2013) Adi Sagiv et al.   BIOGERONTOLOGY

Exome sequencing of senescence-accelerated mice (SAM) reveals deleterious mutations in degenerative disease-causing genes

(2013) Kumpei Tanisawa et al.   BMC GENOMICS

Non-Cell-Autonomous Tumor Suppression by p53

(2013) Amaia Lujambio et al.   CELL

Oxidation-specific epitopes as targets for biotheranostic applications in humans

(2013) Yury I. Miller et al.   CURRENT OPINION IN LIPIDOLOGY

The presence of a truncated base excision repair pathway in human spermatozoa that is mediated by OGG1

(2013) T. B. Smith et al.   JOURNAL OF CELL SCIENCE

Role of the Oxidative DNA Damage Repair Gene OGG1 in Colorectal Tumorigenesis

(2013) Christopher G. Smith et al.   JNCI-Journal of the National Cancer Institute

Plasma Protein Biomarkers of the Geriatric Syndrome of Frailty

(2013) K. Darvin et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Modification of cysteine residues by cyclopentenone prostaglandins: Interplay with redox regulation of protein function

(2013) Clara L. Oeste et al.   MASS SPECTROMETRY REVIEWS

Capacity of Lung Stroma to Educate Dendritic Cells Inhibiting Mycobacteria-Specific T-Cell Response Depends upon Genetic Susceptibility to Tuberculosis

(2013) Marina A. Kapina et al.   PLoS One

Fundamental roles of the innate-like repertoire of natural antibodies in immune homeostasis

(2013) Jaya Vas et al.   Frontiers in Immunology

IgM autoantibodies to distinct apoptosis-associated antigens correlate with protection from cardiovascular events and renal disease in patients with SLE

(2012) Caroline Grönwall et al.   CLINICAL IMMUNOLOGY

The SAMP8 Mouse: A Model to Develop Therapeutic Interventions for Alzheimers Disease

(2012) John E. Morley et al.   CURRENT PHARMACEUTICAL DESIGN

Age-dependent increases in the oxidative damage of DNA, RNA, and their metabolites in normal and senescence-accelerated mice analyzed by LC–MS/MS: Urinary 8-oxoguanosine as a novel biomarker of aging

(2012) Wei Gan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Engulfment and clearance of apoptotic cells based on a GlcNAc-binding lectin-like property of surface vimentin

(2012) Hirohiko Ise et al.   GLYCOBIOLOGY

Biochemical Characterization and N-terminomics Analysis of Leukolysin, the Membrane-type 6 Matrix Metalloprotease (MMP25)

(2012) Amanda E. Starr et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peptide mimotopes of malondialdehyde epitopes for clinical applications in cardiovascular disease

(2012) Shahzada Amir et al.   JOURNAL OF LIPID RESEARCH

Oxidized Phospholipids Are Present on Plasminogen, Affect Fibrinolysis, and Increase Following Acute Myocardial Infarction

(2012) Gregor Leibundgut et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Proteomic Screening of Glycoproteins in Human Plasma for Frailty Biomarkers

(2012) Kinza S. Shamsi et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Lymphocyte activation induces cell surface expression of an immunogenic vimentin isoform

(2012) Senada Bilalic et al.   TRANSPLANT IMMUNOLOGY

Protective Roles of Natural IgM Antibodies

(2012) Caroline Grönwall et al.   Frontiers in Immunology

Age-related changes of Nrf2 and phosphorylated GSK-3β in a mouse model of accelerated aging (SAMP8)

(2011) Koji Tomobe et al.   ARCHIVES OF GERONTOLOGY AND GERIATRICS

Vimentin in cancer and its potential as a molecular target for cancer therapy

(2011) Arun Satelli et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

GROα regulates human embryonic stem cell self-renewal or adoption of a neuronal fate

(2011) Ana Krtolica et al.   DIFFERENTIATION

Astrocytes in the aging brain express characteristics of senescence-associated secretory phenotype

(2011) Antero Salminen et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Divergent human populations show extensive shared IGK rearrangements in peripheral blood B cells

(2011) Katherine Jean Louise Jackson et al.   IMMUNOGENETICS

Relationship of IgG and IgM autoantibodies and immune complexes to oxidized LDL with markers of oxidation and inflammation and cardiovascular events: results from the EPIC-Norfolk Study

(2011) Amir Ravandi et al.   JOURNAL OF LIPID RESEARCH

Proteomic studies on protein modification by cyclopentenone prostaglandins: Expanding our view on electrophile actions

(2011) Beatriz Garzón et al.   Journal of Proteomics

IgM Promotes the Clearance of Small Particles and Apoptotic Microparticles by Macrophages

(2011) Michael L. Litvack et al.   PLoS One

Neuroprotective effects of icariin on memory impairment and neurochemical deficits in senescence-accelerated mouse prone 8 (SAMP8) mice

(2010) Xiao-Li He et al.   BRAIN RESEARCH

Quantitative assessment of markers for cell senescence

(2010) Conor Lawless et al.   EXPERIMENTAL GERONTOLOGY

Melatonin improves inflammation processes in liver of senescence-accelerated prone male mice (SAMP8)

(2010) Sara Cuesta et al.   EXPERIMENTAL GERONTOLOGY

Natural IgM and innate immune collectin SP-D bind to late apoptotic cells and enhance their clearance by alveolar macrophages in vivo

(2010) Michael L. Litvack et al.   MOLECULAR IMMUNOLOGY

Establishing Primary Adult Fibroblast Cultures From Rodents

(2010) Andrei Seluanov et al.   Jove-Journal of Visualized Experiments

The IgM Response to Modified LDL in Experimental Atherosclerosis

(2009) Marcella Van Leeuwen et al.   Annals of the New York Academy of Sciences

Active DNA Demethylation Mediated by DNA Glycosylases

(2009) Jian-Kang Zhu   Annual Review of Genetics

A higher level of IgM anti-oxidized LDL antibodies is associated with a lower severity of coronary atherosclerosis in patients on statins

(2009) L. Garrido-Sánchez et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Low levels of IgM antibodies to phosphorylcholine predict cardiovascular disease in 60-year old men: Effects on uptake of oxidized LDL in macrophages as a potential mechanism

(2009) Ulf de Faire et al.   JOURNAL OF AUTOIMMUNITY

Recruitment of vimentin to the cell surface by  3 integrin and plectin mediates adhesion strength

(2009) R. Bhattacharya et al.   JOURNAL OF CELL SCIENCE

Interleukin-6 maintains bone marrow-derived mesenchymal stem cell stemness by an ERK1/2-dependent mechanism

(2009) Katie L. Pricola et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Oxidation-specific epitopes are dominant targets of innate natural antibodies in mice and humans

(2009) Meng-Yun Chou et al.   JOURNAL OF CLINICAL INVESTIGATION

IgM Antibodies to Apoptosis-Associated Determinants Recruit C1q and Enhance Dendritic Cell Phagocytosis of Apoptotic Cells

(2009) Yifang Chen et al.   JOURNAL OF IMMUNOLOGY

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion

(2009) Francis Rodier et al.   NATURE CELL BIOLOGY

Neurochemistry, Neuropathology, and Heredity in SAMP8: A Mouse Model of Senescence

(2009) Koji Tomobe et al.   NEUROCHEMICAL RESEARCH

Senescence of Activated Stellate Cells Limits Liver Fibrosis

(2008) Valery Krizhanovsky et al.   CELL

Naturally occurring auto-antibodies in homeostasis and disease

(2008) Hans U. Lutz et al.   TRENDS IN IMMUNOLOGY

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor

(2008) Jean-Philippe Coppé et al.   PLOS BIOLOGY