Screen for reactivation of MeCP2 on the inactive X chromosome identifies the BMP/TGF-β superfamily as a regulator of XIST expression

De Novo Loss-of-Function Mutations in USP9X Cause a Female-Specific Recognizable Syndrome with Developmental Delay and Congenital Malformations

(2016) Margot R.F. Reijnders et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Female mice lacking Xist RNA show partial dosage compensation and survive to term

(2016) Lin Yang et al.   GENES & DEVELOPMENT

De novo mutations ofKIAA2022in females cause intellectual disability and intractable epilepsy

(2016) Iris M de Lange et al.   JOURNAL OF MEDICAL GENETICS

A high-throughput small molecule screen identifies synergism between DNA methylation and Aurora kinase pathways for X reactivation

(2016) Derek Lessing et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dosage compensation of the sex chromosomes and autosomes

(2016) Christine M. Disteche   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Fitting the Puzzle Pieces: the Bigger Picture of XCI

(2016) Cheryl Maduro et al.   TRENDS IN BIOCHEMICAL SCIENCES

Bone Morphogenetic Proteins

(2016) Takenobu Katagiri et al.   Cold Spring Harbor Perspectives in Biology

TGF-β Signaling from Receptors to Smads

(2016) Akiko Hata et al.   Cold Spring Harbor Perspectives in Biology

Mutations in DDX3X Are a Common Cause of Unexplained Intellectual Disability with Gender-Specific Effects on Wnt Signaling

(2015) Lot Snijders Blok et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3

(2015) Colleen A. McHugh et al.   NATURE

Wild-type microglia do not reverse pathology in mouse models of Rett syndrome

(2015) Jieqi Wang et al.   NATURE

A comprehensive Xist interactome reveals cohesin repulsion and an RNA-directed chromosome conformation

(2015) A. Minajigi et al.   SCIENCE

A high-throughput screen of inactive X chromosome reactivation identifies the enhancement of DNA demethylation by 5-aza-2′-dC upon inhibition of ribonucleotide reductase

(2015) Alissa Minkovsky et al.   Epigenetics & Chromatin

Loss of Pol32 in Drosophila melanogaster Causes Chromosome Instability and Suppresses Variegation

(2015) Patrizia Tritto et al.   PLoS One

TGF-β signaling alters the pattern of liver tumorigenesis induced by Pten inactivation

(2014) S M Morris et al.   ONCOGENE

Genetic and pharmacological reactivation of the mammalian inactive X chromosome

(2014) S. Bhatnagar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Mbd1-Atf7ip-Setdb1 pathway contributes to the maintenance of X chromosome inactivation

(2014) Alissa Minkovsky et al.   Epigenetics & Chromatin

A prominent and conserved role for YY1 in Xist transcriptional activation

(2014) Mélanie Makhlouf et al.   Nature Communications

Genome-wide RNAi screens in human brain tumor isolates reveal a novel viability requirement for PHF5A

(2013) C. G. Hubert et al.   GENES & DEVELOPMENT

Characterization of Negative Feedback Network Motifs in the TGF-β Signaling Pathway

(2013) Daniel Nicklas et al.   PLoS One

Acetyl-CoA Carboxylase Regulates Global Histone Acetylation

(2012) Luciano Galdieri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibiting the Inhibitor: The Role of RNF12 in TGF-β Superfamily Signaling

(2012) Caroline S. Hill   MOLECULAR CELL

RNF12 Controls Embryonic Stem Cell Fate and Morphogenesis in Zebrafish Embryos by Targeting Smad7 for Degradation

(2012) Long Zhang et al.   MOLECULAR CELL

HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle

(2012) Matthew A. Deardorff et al.   NATURE

RNF12 initiates X-chromosome inactivation by targeting REX1 for degradation

(2012) Cristina Gontan et al.   NATURE

Multilayered chromatin analysis reveals E2f, Smad and Zfx as transcriptional regulators of histones

(2012) David Gokhman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cancer-Specific Requirement for BUB1B/BUBR1 in Human Brain Tumor Isolates and Genetically Transformed Cells

(2012) Yu Ding et al.   Cancer Discovery

Mutations and variants in the cohesion factor genesNIPBL,SMC1A, andSMC3in a cohort of 30 unrelated patients with Cornelia de Lange syndrome

(2010) Juan Pié et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Global survey of escape from X inactivation by RNA-sequencing in mouse

(2010) F. Yang et al.   GENOME RESEARCH

Drosophila CAF-1 regulates HP1-mediated epigenetic silencing and pericentric heterochromatin stability

(2010) H. Huang et al.   JOURNAL OF CELL SCIENCE

Maternal Rnf12/RLIM is required for imprinted X-chromosome inactivation in mice

(2010) JongDae Shin et al.   NATURE

RNF12 Is an X-Encoded Dose-Dependent Activator of X Chromosome Inactivation

(2009) Iris Jonkers et al.   CELL

Structure–activity relationship study of bone morphogenetic protein (BMP) signaling inhibitors

(2008) Gregory D. Cuny et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS