Trade-offs between enzyme fitness and solubility illuminated by deep mutational scanning
出版年份 2017 全文链接
标题
Trade-offs between enzyme fitness and solubility illuminated by deep mutational scanning
作者
关键词
-
出版物
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 114, Issue 9, Pages 2265-2270
出版商
Proceedings of the National Academy of Sciences
发表日期
2017-02-15
DOI
10.1073/pnas.1614437114
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability
- (2016) Adi Goldenzweig et al. MOLECULAR CELL
- Plasmid-based one-pot saturation mutagenesis
- (2016) Emily E Wrenbeck et al. NATURE METHODS
- Software for the analysis and visualization of deep mutational scanning data
- (2015) Jesse D Bloom BMC BIOINFORMATICS
- Repurposing a Bacterial Quality Control Mechanism to Enhance Enzyme Production in Living Cells
- (2015) Jason T. Boock et al. JOURNAL OF MOLECULAR BIOLOGY
- The CamSol Method of Rational Design of Protein Mutants with Enhanced Solubility
- (2015) Pietro Sormanni et al. JOURNAL OF MOLECULAR BIOLOGY
- Comprehensive Sequence-Flux Mapping of a Levoglucosan Utilization Pathway in E. coli
- (2015) Justin R. Klesmith et al. ACS Synthetic Biology
- High-Resolution Sequence-Function Mapping of Full-Length Proteins
- (2015) Caitlin A. Kowalsky et al. PLoS One
- A Comprehensive, High-Resolution Map of a Gene’s Fitness Landscape
- (2014) Elad Firnberg et al. MOLECULAR BIOLOGY AND EVOLUTION
- Comprehensive mutational scanning of a kinasein vivoreveals substrate-dependent fitness landscapes
- (2014) Alexandre Melnikov et al. NUCLEIC ACIDS RESEARCH
- Community-Wide Assessment of Protein-Interface Modeling Suggests Improvements to Design Methodology
- (2011) Sarel J. Fleishman et al. JOURNAL OF MOLECULAR BIOLOGY
- Deep mutational scanning: assessing protein function on a massive scale
- (2011) Carlos L. Araya et al. TRENDS IN BIOTECHNOLOGY
- Role of conformational sampling in computing mutation-induced changes in protein structure and stability
- (2010) Elizabeth H. Kellogg et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Stability effects of mutations and protein evolvability
- (2009) Nobuhiko Tokuriki et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Directed evolution of an extremely stable fluorescent protein
- (2009) C. Kiss et al. PROTEIN ENGINEERING DESIGN & SELECTION
- Intense Neutral Drifts Yield Robust and Evolvable Consensus Proteins
- (2008) Shimon Bershtein et al. JOURNAL OF MOLECULAR BIOLOGY
- How Protein Stability and New Functions Trade Off
- (2008) Nobuhiko Tokuriki et al. PLoS Computational Biology
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search