β-III-spectrin spinocerebellar ataxia type 5 mutation reveals a dominant cytoskeletal mechanism that underlies dendritic arborization

Periodic actin structures in neuronal axons are required to maintain microtubules

(2017) Yue Qu et al.   MOLECULAR BIOLOGY OF THE CELL

Genetic defects in β-spectrin and tau sensitize C. elegans axons to movement-induced damage via torque-tension coupling

(2017) Michael Krieg et al.   eLife

A Novel Missense Mutation in the Spectrin Beta Nonerythrocytic 2 Gene Likely Associated with Spinocerebellar Ataxia Type 5

(2016) Xu-Sheng Huang et al.   CHINESE MEDICAL JOURNAL

Prevalent presence of periodic actin–spectrin-based membrane skeleton in a broad range of neuronal cell types and animal species

(2016) Jiang He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Subcortical cytoskeleton periodicity throughout the nervous system

(2016) Elisa D’Este et al.   Scientific Reports

A human β-III-spectrin spinocerebellar ataxia type 5 mutation causes high-affinity F-actin binding

(2016) Adam W. Avery et al.   Scientific Reports

Removal of Drosophila Muscle Tissue from Larval Fillets for Immunofluorescence Analysis of Sensory Neurons and Epidermal Cells

(2016) Conrad M. Tenenbaum et al.   Jove-Journal of Visualized Experiments

Multicolour Multilevel STED nanoscopy of Actin/Spectrin Organization at Synapses

(2016) Sven C. Sidenstein et al.   Scientific Reports

Periodic F-actin structures shape the neck of dendritic spines

(2016) Julia Bär et al.   Scientific Reports

STED Nanoscopy Reveals the Ubiquity of Subcortical Cytoskeleton Periodicity in Living Neurons

(2015) Elisa D’Este et al.   Cell Reports

The Ret receptor regulates sensory neuron dendrite growth and integrin mediated adhesion

(2015) Peter Soba et al.   eLife

 -III spectrin underpins ankyrin R function in Purkinje cell dendritic trees: protein complex critical for sodium channel activity is impaired by SCA5-associated mutations

(2014) Y. L. Clarkson et al.   HUMAN MOLECULAR GENETICS

Spectrin Tetramer Formation Is Not Required for Viable Development inDrosophila

(2014) Mansi R. Khanna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Japanese SCA5 family with a novel three-nucleotide in-frame deletion mutation in the SPTBN2 gene: a clinical and genetic study

(2014) Ying Wang et al.   JOURNAL OF HUMAN GENETICS

Mutant  -III Spectrin Causes mGluR1  Mislocalization and Functional Deficits in a Mouse Model of Spinocerebellar Ataxia Type 5

(2014) K. R. Armbrust et al.   JOURNAL OF NEUROSCIENCE

Developmental mechanism of the periodic membrane skeleton in axons

(2014) Guisheng Zhong et al.   eLife

Sex-Specific Weight Loss Mediates Sexual Size Dimorphism in Drosophila melanogaster

(2013) Nicholas D. Testa et al.   PLoS One

A Family with Spinocerebellar Ataxia Type 5 Found to Have a Novel Missense Mutation within a SPTBN2 Spectrin Repeat

(2012) Ellen Cho et al.   CEREBELLUM

Case of Infantile Onset Spinocerebellar Ataxia Type 5

(2012) Francois-Dominique Jacob et al.   JOURNAL OF CHILD NEUROLOGY

Rational design of true monomeric and bright photoactivatable fluorescent proteins

(2012) Mingshu Zhang et al.   NATURE METHODS

Mitochondrial dysfunction and Purkinje cell loss in autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS)

(2012) M. Girard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Actin, Spectrin, and Associated Proteins Form a Periodic Cytoskeletal Structure in Axons

(2012) K. Xu et al.   SCIENCE

Mutations in the N-terminal Actin-Binding Domain of Filamin C Cause a Distal Myopathy

(2011) Rachael M. Duff et al.   AMERICAN JOURNAL OF HUMAN GENETICS

 -III Spectrin Is Critical for Development of Purkinje Cell Dendritic Tree and Spine Morphogenesis

(2011) Y. Gao et al.   JOURNAL OF NEUROSCIENCE

Pathogenic polyglutamine proteins cause dendrite defects associated with specific actin cytoskeletal alterations in Drosophila

(2011) S. B. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The single dendritic branch as a fundamental functional unit in the nervous system

(2010) Tiago Branco et al.   CURRENT OPINION IN NEUROBIOLOGY

 -III spectrin mutation L253P associated with spinocerebellar ataxia type 5 interferes with binding to Arp1 and protein trafficking from the Golgi

(2010) Y. L. Clarkson et al.   HUMAN MOLECULAR GENETICS

Spectrin mutations that cause spinocerebellar ataxia type 5 impair axonal transport and induce neurodegeneration inDrosophila

(2010) Damaris N. Lorenzo et al.   JOURNAL OF CELL BIOLOGY

Loss of  -III Spectrin Leads to Purkinje Cell Dysfunction Recapitulating the Behavior and Neuropathology of Spinocerebellar Ataxia Type 5 in Humans

(2010) E. M. Perkins et al.   JOURNAL OF NEUROSCIENCE

Transgene Rescue Identifies an Essential Function for Drosophila β Spectrin in the Nervous System and a Selective Requirement for Ankyrin-2–binding Activity

(2010) G. Harper Mazock et al.   MOLECULAR BIOLOGY OF THE CELL

A Guide to Simple and Informative Binding Assays

(2010) Thomas D. Pollard   MOLECULAR BIOLOGY OF THE CELL

Branching out: mechanisms of dendritic arborization

(2010) Yuh-Nung Jan et al.   NATURE REVIEWS NEUROSCIENCE

Opening of tandem calponin homology domains regulates their affinity for F-actin

(2010) Vitold E Galkin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Targeted deletion of  III spectrin impairs synaptogenesis and generates ataxic and seizure phenotypes

(2010) M. C. Stankewich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Skeletal dysplasias due to filamin A mutations result from a gain-of-function mechanism distinct from allelic neurological disorders†

(2009) Alice R. Clark et al.   HUMAN MOLECULAR GENETICS

A Two-amino Acid Mutation Encountered in Duchenne Muscular Dystrophy Decreases Stability of the Rod Domain 23 (R23) Spectrin-like Repeat of Dystrophin

(2009) Sébastien Legardinier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Disease-associated Substitutions in the Filamin B Actin Binding Domain Confer Enhanced Actin Binding Affinity in the Absence of Major Structural Disturbance: Insights from the Crystal Structures of Filamin B Actin Binding Domains

(2009) Gregory M. Sawyer et al.   JOURNAL OF MOLECULAR BIOLOGY

Exploiting position effects and the gypsy retrovirus insulator to engineer precisely expressed transgenes

(2008) Michele Markstein et al.   NATURE GENETICS

Drosophila Ankyrin 2 Is Required for Synaptic Stability

(2008) Iris Koch et al.   NEURON

A Presynaptic Giant Ankyrin Stabilizes the NMJ through Regulation of Presynaptic Microtubules and Transsynaptic Cell Adhesion

(2008) Jan Pielage et al.   NEURON