Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit

mir-34b/c and mir-449a/b/c are required for spermatogenesis, but not for the first cleavage division in mice

(2015) S. Yuan et al.   Biology Open

miR-34: from bench to bedside

(2015) Massimiliano Agostini et al.   Oncotarget

A positive feedback between p53 and miR-34 miRNAs mediates tumor suppression

(2014) N. Okada et al.   GENES & DEVELOPMENT

MiR-34a deficiency accelerates medulloblastoma formationin vivo

(2014) Theresa Thor et al.   INTERNATIONAL JOURNAL OF CANCER

IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis

(2014) Matjaz Rokavec et al.   JOURNAL OF CLINICAL INVESTIGATION

miR-34/449 miRNAs are required for motile ciliogenesis by repressing cp110

(2014) Rui Song et al.   NATURE

Two miRNA clusters, miR-34b/c and miR-449, are essential for normal brain development, motile ciliogenesis, and spermatogenesis

(2014) J. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-34 Cooperates with p53 in Suppression of Prostate Cancer by Joint Regulation of Stem Cell Compartment

(2014) Chieh-Yang Cheng et al.   Cell Reports

Oligoasthenoteratozoospermia and Infertility in Mice Deficient for miR-34b/c and miR-449 Loci

(2014) Stefano Comazzetto et al.   PLoS Genetics

MicroRNA-34a regulates cardiac ageing and function

(2013) Reinier A. Boon et al.   NATURE

MicroRNA-449 and MicroRNA-34b/c Function Redundantly in Murine Testes by Targeting E2F Transcription Factor-Retinoblastoma Protein (E2F-pRb) Pathway

(2012) Jianqiang Bao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

miR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2

(2012) Jianwen Wei et al.   JOURNAL OF CELL BIOLOGY

Intact p53-Dependent Responses in miR-34–Deficient Mice

(2012) Carla P. Concepcion et al.   PLoS Genetics

MicroRNA-449 in cell fate determination

(2011) Muriel Lizé et al.   CELL CYCLE

Control of vertebrate multiciliogenesis by miR-449 through direct repression of the Delta/Notch pathway

(2011) Brice Marcet et al.   NATURE CELL BIOLOGY

miR-34 miRNAs provide a barrier for somatic cell reprogramming

(2011) Yong Jin Choi et al.   NATURE CELL BIOLOGY

Genome-wide analysis reveals conserved and divergent features of Notch1/RBPJ binding in human and murine T-lymphoblastic leukemia cells

(2011) H. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Capture of MicroRNA–Bound mRNAs Identifies the Tumor Suppressor miR-34a as a Regulator of Growth Factor Signaling

(2011) Ashish Lal et al.   PLoS Genetics

MicroRNA-449a levels increase by several orders of magnitude during mucociliary differentiation of airway epithelia

(2010) Muriel Lizé et al.   CELL CYCLE

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Notch signaling controls the balance of ciliated and secretory cell fates in developing airways

(2009) P.-N. Tsao et al.   DEVELOPMENT

miR-449a and miR-449b are direct transcriptional targets of E2F1 and negatively regulate pRb-E2F1 activity through a feedback loop by targeting CDK6 and CDC25A

(2009) X. Yang et al.   GENES & DEVELOPMENT

miR-449a targets HDAC-1 and induces growth arrest in prostate cancer

(2009) E J Noonan et al.   ONCOGENE

Downregulation of CCND1 and CDK6 by miR-34a induces cell cycle arrest

(2008) Fang Sun et al.   FEBS LETTERS

The impact of microRNAs on protein output

(2008) Daehyun Baek et al.   NATURE

The MYCN oncogene is a direct target of miR-34a

(2008) J S Wei et al.   ONCOGENE

A microRNA DNA methylation signature for human cancer metastasis

(2008) A. Lujambio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA