Inhibition of acute lethal pulmonary inflammation by the IDO–AhR pathway

Lung parenchyma-derived IL-6 promotes IL-17A-dependent acute lung injury after allogeneic stem cell transplantation

(2015) A. Varelias et al.   BLOOD

 -Mannan induces Th17-mediated pulmonary graft-versus-host disease in mice

(2015) H. Uryu et al.   BLOOD

A Distinct Function of Regulatory T Cells in Tissue Protection

(2015) Nicholas Arpaia et al.   CELL

Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR

(2015) Ulrike M. Litzenburger et al.   Oncotarget

Histone deacetylase inhibition regulates inflammation and enhances Tregs after allogeneic hematopoietic cell transplantation in humans

(2014) S. W. Choi et al.   BLOOD

Aryl hydrocarbon receptor control of a disease tolerance defence pathway

(2014) Alban Bessede et al.   NATURE

Current and emerging strategies for the prevention of graft-versus-host disease

(2014) Sung Won Choi et al.   Nature Reviews Clinical Oncology

Th17/Treg Imbalance in Murine Cystic Fibrosis Is Linked to Indoleamine 2,3-Dioxygenase Deficiency but Corrected by Kynurenines

(2013) Rossana G. Iannitti et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Alveolar Macrophages Contribute to Respiratory Tolerance by Inducing FoxP3 Expression in Naive T Cells

(2013) Michelle M. Coleman et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Cyclosporine A Drives a Th17- and Th2-Mediated Posttransplant Obliterative Airway Disease

(2013) P. H. Lemaître et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Vorinostat plus tacrolimus and mycophenolate to prevent graft-versus-host disease after related-donor reduced-intensity conditioning allogeneic haemopoietic stem-cell transplantation: a phase 1/2 trial

(2013) Sung Won Choi et al.   LANCET ONCOLOGY

Role of Tissue Protection in Lethal Respiratory Viral-Bacterial Coinfection

(2013) A. M. Jamieson et al.   SCIENCE

Immune insufficiency during GVHD is due to defective antigen presentation within dendritic cell subsets

(2012) K. A. Markey et al.   BLOOD

Brain indoleamine 2,3-dioxygenase contributes to the comorbidity of pain and depression

(2012) Hyangin Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

The Role of Alveolar Epithelial Cells in Initiating and Shaping Pulmonary Immune Responses: Communication between Innate and Adaptive Immune Systems

(2012) Olga D. Chuquimia et al.   PLoS One

Indoleamine 2,3 dioxygenase and metabolic control of immune responses

(2012) David H. Munn et al.   TRENDS IN IMMUNOLOGY

Contribution of IL-17–producing γδ T cells to the efficacy of anticancer chemotherapy

(2011) Yuting Ma et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Pharmacodynamic Evaluation of the Target Efficacy of SB939, an Oral HDAC Inhibitor with Selectivity for Tumor Tissue

(2011) V. Novotny-Diermayr et al.   MOLECULAR CANCER THERAPEUTICS

An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor

(2011) Christiane A. Opitz et al.   NATURE

Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells

(2011) Maria T Pallotta et al.   NATURE IMMUNOLOGY

Histone deacetylases as regulators of inflammation and immunity

(2011) Melanie R. Shakespear et al.   TRENDS IN IMMUNOLOGY

Induction of IDO-1 by Immunostimulatory DNA Limits Severity of Experimental Colitis

(2010) M. A. Ciorba et al.   JOURNAL OF IMMUNOLOGY

SB939, a Novel Potent and Orally Active Histone Deacetylase Inhibitor with High Tumor Exposure and Efficacy in Mouse Models of Colorectal Cancer

(2010) V. Novotny-Diermayr et al.   MOLECULAR CANCER THERAPEUTICS

Inducing the tryptophan catabolic pathway, indoleamine 2,3-dioxygenase (IDO), for suppression of graft-versus-host disease (GVHD) lethality

(2009) L. K. Jasperson et al.   BLOOD

Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft-versus-host disease

(2009) T. Yi et al.   BLOOD

Interferon-γ-Responsive Nonhematopoietic Cells Regulate the Immune Response to Mycobacterium tuberculosis

(2009) Ludovic Desvignes et al.   IMMUNITY

Lung interstitial macrophages alter dendritic cell functions to prevent airway allergy in mice

(2009) Denis Bedoret et al.   JOURNAL OF CLINICAL INVESTIGATION

Cutting Edge: Negative Regulation of Dendritic Cells through Acetylation of the Nonhistone Protein STAT-3

(2009) Yaping Sun et al.   JOURNAL OF IMMUNOLOGY

Interferon-γ Regulates Idiopathic Pneumonia Syndrome, a Th17+CD4+T-Cell–mediated Graft-versus-Host Disease

(2008) Nora Mauermann et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The impact of soluble tumor necrosis factor receptor etanercept on the treatment of idiopathic pneumonia syndrome after allogeneic hematopoietic stem cell transplantation

(2008) G. A. Yanik et al.   BLOOD

Absence of donor Th17 leads to augmented Th1 differentiation and exacerbated acute graft-versus-host disease

(2008) T. Yi et al.   BLOOD

The role of indoleamine 2,3-dioxygenase in the induction of immune tolerance: focus on hematology

(2008) A. Curti et al.   BLOOD

Histone deacetylase inhibition modulates indoleamine 2,3-dioxygenase–dependent DC functions and regulates experimental graft-versus-host disease in mice

(2008) Pavan Reddy et al.   JOURNAL OF CLINICAL INVESTIGATION

Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease

(2008) Luigina Romani et al.   NATURE

Indoleamine 2,3-dioxygenase is a critical regulator of acute graft-versus-host disease lethality

(2007) L. K. Jasperson et al.   BLOOD