Article
Veterinary Sciences
Kelly Buckle, Rudolfo Bueno, Andrew McFadden, Mary van Andel, Richard Spence, Carolyn Hamill, Wendi Roe, Emilie Vallee, Fernanda Castillo-Alcala, Ronel Abila, Blesilda Verin, Bolortuya Purevsuren, Ashish Sutar, Htun Htun Win, Myo Thiha, Khin Ohnmar Lwin, Syseng Khounsy, Sengxay Phonthasy, Viliddeth Souriya, Chattouphone Keokhamphet, Jonathan Arzt, Anna Ludi, Valerie Mioulet
Summary: This study investigated the presence of FMDV RNA in healthy cattle and buffalo in Laos and Myanmar, revealing that 7.3% of animals had detectable FMDV RNA on their mucosal surfaces, suggesting subclinical infection may play a role in FMD epidemiology. Additionally, a high percentage of animals tested positive for NSP antibodies, indicating previous exposure to FMDV.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Environmental Sciences
Zhicheng Du, Philip Hopke, Tia Marks, Shao Lin, Wangjian Zhang, Yuantao Hao
Summary: This study investigated the relationship between meteorological factors and the risk of hand, foot, and mouth disease (HFMD) in four cities in Guangdong Province. The results showed nonlinear and interactive relationships between temperature, humidity, and HFMD risk, as well as the impact of wind speed and sunshine duration on other meteorological factors. Additionally, increased gross domestic product per capita and per capital area of parks and green land were found to strengthen the interactive effects of humidity on other meteorological factors.
ENVIRONMENTAL RESEARCH LETTERS
(2022)
Article
Virology
Jonathan Arzt, Ian H. Fish, Miranda R. Bertram, George R. Smoliga, Ethan J. Hartwig, Steven J. Pauszek, Lauren Holinka-Patterson, Fayna C. Diaz-San Segundo, Tatjana Sitt, Elizabeth Rieder, Carolina Stenfeldt
Summary: Research showed that cattle can be simultaneously infected with two different serotypes of foot-and-mouth disease virus (FMDV), with different outcomes depending on the timing of exposure to the viruses. Dominant interserotypic recombinant FMDVs were discovered in upper respiratory tract samples of superinfected animals, indicating the potential role of persistently infected FMDV carriers in generating novel viral strains.
JOURNAL OF VIROLOGY
(2021)
Article
Agriculture, Dairy & Animal Science
Mohamed Jiffry Athambawa, Satoko Kubota, Hiroichi Kono
Summary: This study identified that social and farm factors significantly influence the knowledge of foot-and-mouth disease (FMD) and vaccination behavior. It is recommended that Sri Lanka implement a livestock educational training program to enhance participation in the FMD control plan.
TROPICAL ANIMAL HEALTH AND PRODUCTION
(2021)
Article
Infectious Diseases
Nlingisisi Dombole Babayani, Odireleng Idy Thololwane
Summary: In this study, we used a qualitative risk analysis method to assess the risk of a foot-and-mouth disease outbreak in zone 2 of Botswana due to interaction between cattle and buffalo. The assessed risk was rated as "moderate" and had a moderate level of uncertainty, suggesting the need for mitigation options before allowing the import of cattle and cattle products from zone 2. Due to high costs and challenges posed by elephants, we concluded that the national goal of eradicating foot-and-mouth disease in all livestock-rearing areas should be revised to a more achievable outcome for zone 2. We recommend implementing husbandry management practices and marketing approaches that acknowledge the co-existence of cattle and wildlife in zone 2 and focus on food product safety guarantees along the value chain, which is crucial for the sustainability of foot-and-mouth disease management and livelihoods in zone 2.
TRANSBOUNDARY AND EMERGING DISEASES
(2022)
Article
Veterinary Sciences
Gerelmaa Ulziibat, Eran Raizman, Amarsanaa Lkhagvasuren, Chris J. M. Bartels, Orgikhbayar Oyun-Erdene, Bodisaikhan Khishgee, Clare Browning, Donald P. King, Anna B. Ludi, Nicholas A. Lyons
Summary: Vaccines are crucial in controlling foot-and-mouth disease outbreaks in Mongolia, but logistical challenges make delivering a two-dose primary vaccination course difficult in nomadic pastoralist systems. While highly potent vaccines have shown prolonged immunity, their effectiveness in field conditions with commercially available vaccines has not been confirmed. This study compared neutralizing titres in Mongolian sheep and cattle vaccinated with either a two-dose primary course or a single double-dose vaccine over a 6-month period. The results suggest that the single double-dose regimen may be a cost-effective approach for FMD control in Mongolia.
FRONTIERS IN VETERINARY SCIENCE
(2023)
Article
Virology
Julie Adamchick, Karl M. Rich, Andres M. Perez
Summary: This study estimated the probability of beef cattle infected with FMD reaching slaughter in East African countries and found the risk to be high in both Kenya and Uganda. Interventions to reduce the probability of FMD transmission at slaughter should consider factors like likelihood of acquiring new infections and commingling with other cattle.
Article
Pediatrics
Peiqing Li, Yuge Huang, Danping Zhu, Sida Yang, Dandan Hu
Summary: EV71, lifestyle habits, frequent hospital visits, and symptoms are risk factors for severe HFMD in children in China, while early diagnosis and admission to higher-level hospitals are protective factors.
FRONTIERS IN PEDIATRICS
(2021)
Article
Infectious Diseases
Glen Guyver-Fletcher, Erin E. Gorsich, Michael J. Tildesley
Summary: Foot-and-mouth disease (FMD) is a deadly and economically impactful disease in livestock, still prevalent in certain regions of Asia and Africa. The controversy of whether carrier livestock can infect susceptible animals remains, but theoretically carrier transmission can support the persistence of FMD in endemic regions.
TRANSBOUNDARY AND EMERGING DISEASES
(2022)
Article
Infectious Diseases
Carolina Stenfeldt, Miranda R. Bertram, Haillie C. Meek, Ethan J. Hartwig, George R. Smoliga, Megan C. Niederwerder, Diego G. Diel, Scott A. Dee, Jonathan Arzt
Summary: The study investigated the infectivity of foot-and-mouth disease virus (FMDV) in commercial pig feed and feed ingredients, determining the minimum infectious dose required for pigs to develop the disease. The results indicated that FMDV can remain infectious in pig feed ingredients for durations compatible with transoceanic transport, with variations in feeding conditions and virus strains affecting the probability of infection. This information can be used to model the risk of FMDV incursions and regulate feed importation to minimize the risk of unintentional importation.
TRANSBOUNDARY AND EMERGING DISEASES
(2022)
Article
Veterinary Sciences
Mesfin Shurbe, Bekahegn Simeon, Wasihun Seyoum, Ayelech Muluneh, Ephrem Tora, Edget Abayneh
Summary: This study revealed a high seroprevalence of foot and mouth disease (FMD) in the study area and a lack of knowledge among farmers regarding disease transmission and vaccine availability. It highlights the need for FMD vaccination campaigns and educational efforts to raise awareness among smallholder farmers about the disease transmission, FMD vaccine schedule, and vaccination importance.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Veterinary Sciences
Orapun Arjkumpa, Catalina Picasso-Risso, Andres Perez, Veerasak Punyapornwithaya
Summary: This study described FMD outbreaks among smallholder cattle farms in northern Thailand and computed the effective reproductive number for outbreaks caused by different FMDV serotypes. The results showed that FMD transmission in cattle at the subdistrict level in northern Thailand was not controlled, indicating the endemicity of the disease in the region. Enhanced FMD monitoring and control strategies are needed in northern Thailand.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Immunology
Michael Puckette, Benjamin A. A. Clark, Jose Barrera, John G. G. Neilan, Max V. V. Rasmussen
Summary: We evaluated four DNA vaccine candidates for their ability to produce virus-like particles (VLPs) and elicit a protective immune response against Foot-and-mouth disease virus (FMDV) in cattle. However, none of the DNA vaccine candidates elicited protection from clinical disease when administered independently. Administration of pTarget O1P1-3C plasmid enhanced neutralizing antibody titers when used as a priming dose prior to administration of a conditionally licensed adenovirus-vectored FMD vaccine.
Article
Microbiology
Carolina Stenfeldt, Ian Fish, Haillie C. Meek, Jonathan Arzt
Summary: This study investigates the pathogenesis of FMDV coinfections in cattle, showing that simultaneous infection does not lead to recombinant viruses, but heterologous superinfection of persistently infected carrier cattle does. The study also demonstrates a multifocal and heterogeneous distribution of FMDV infection in the nasopharyngeal tissue. These findings highlight the importance of FMDV carriers in the emergence of new recombinant strains.
Article
Multidisciplinary Sciences
Thilini W. Hettiarachchi, Buddhi N. T. W. Fernando, Thilini Sudeshika, Zeid Badurdeen, Shuchi Anand, Ajith Kularatne, Sulochana Wijetunge, Hemalika T. K. Abeysundara, Nishantha Nanayakkara
Summary: The study found that patients with CKDu have a low prevalence and risk for CVD, implying that a majority are likely to survive to reach end-stage kidney disease. This highlights the need for developing strategies to minimize the progression of CKDu to end-stage renal disease.
Article
Parasitology
Watcharapol Suyapoh, Sirikachorn Tangkawattana, Sutas Suttiprapa, Veerasak Punyapornwithaya, Prasarn Tangkawattana, Banchob Sripa
Summary: This study found that liver fluke infection induces a high level of inflammation and histopathological changes in the biliary system, while co-infection with cagA-positive H. pylori leads to more severe biliary pathology, especially predisposing to precancerous lesions of cholangiocarcinoma in areas of inflammation. Additionally, O. viverrini co-infected with cagA-positive H. pylori exhibited a higher proliferation index and periductal fibrosis compared to other groups.
Article
Agriculture, Dairy & Animal Science
Chalutwan Sansamur, Anuwat Wiratsudakul, Arisara Charoenpanyanet, Veerasak Punyapornwithaya
Summary: Foot and mouth disease is endemic in Thailand and Southeast Asia. This study used capture-recapture methods to estimate the number of dairy farms in Chiang Mai that had experienced FMD outbreaks, revealing a higher sensitivity of the active survey approach compared to the passive method.
TROPICAL ANIMAL HEALTH AND PRODUCTION
(2021)
Article
Agriculture, Dairy & Animal Science
Manusvee Kaikuntod, Orapun Arjkumpa, Doolyawat Kladkempetch, Shinya Fukumoto, Kriangkrai Thongkorn, Chavalit Boonyapakorn, Veerasak Punyapornwithaya, Saruda Tiwananthagorn
Summary: Filariasis is emerging as a public health concern in tropical and subtropical areas, commonly found in southeast Asian countries. This study confirmed the presence of Dirofilaria immitis and Brugia pahangi in free-roaming community dogs in Northern Thailand. The geographic distribution showed a higher prevalence of B. pahangi than D. immitis at higher altitudes between 400 and 800 m.
Article
Food Science & Technology
Kunnanut Klaharn, Duangporn Pichpol, Tongkorn Meeyam, Dirk Pfeiffer, Anucha Moomon, Patpong Lohaanukul, Veerasak Punyapornwithaya
Summary: This study aimed to compare bacterial contamination levels in meat samples from pig slaughterhouses in six regions of Thailand. Differences in bacterial contamination levels were found between regions, with varying levels of different types of bacteria contamination.
Article
Agriculture, Dairy & Animal Science
Veerasak Punyapornwithaya, Katechan Jampachaisri, Orapun Arjkumpa, Methanon Moonpho, Kunnanut Klaharn, Naovarat Kampoosiri, Chalutwan Sansamur
Summary: This study investigated the data from selected dairy cooperatives in northern and central regions of Thailand and found that more than 70% of dairy farmers benefited from the PPBMQ. Particularly, farmers in the northern region received more benefits, while those in the central region lost benefits mainly due to somatic cell counts and solids not fat.
Article
Multidisciplinary Sciences
Kunnanut Klaharn, Duangporn Pichpol, Tongkorn Meeyam, Thanida Harintharanon, Patpong Lohaanukul, Veerasak Punyapornwithaya
Summary: Slaughterhouses are a major source of bacterial contamination in poultry meat and products. A study identified non-compliance of meat samples and identified risk factors associated with the contamination. Improper scalding and evisceration processes, open or semi-closed system slaughterhouses, and lack of specific slaughtering area equipment were found to increase the risk of bacterial contamination.
Article
Virology
Veerasak Punyapornwithaya, Pradeep Mishra, Chalutwan Sansamur, Dirk Pfeiffer, Orapun Arjkumpa, Rotchana Prakotcheo, Thanis Damrongwatanapokin, Katechan Jampachaisri
Summary: This study aimed to model and forecast the monthly number of foot and mouth disease (FMD) outbreak episodes in Thailand using time-series methods. The results showed a stable trend in FMD episodes from 2010 to 2020, with an increasing trend observed from 2014 to 2020. The forecasts indicated a rising trend in FMD episodes in Thailand, highlighting the need for strengthened control strategies and measures.
Article
Virology
Ayesha Anwar, Kannika Na-Lampang, Narin Preyavichyapugdee, Veerasak Punyapornwithaya
Summary: This study analyzes LSD outbreak reports from 2005 to 2022 and predicts the trends and change points in Africa, Europe, and Asia. The findings show significant change points in each continent and forecast a rise in the number of LSD reports in Africa and steady numbers in Europe. Additionally, different models predict different patterns in Asia.
Article
Agriculture, Dairy & Animal Science
Jaruwan Khonmee, Janine L. Brown, Anabel Lopez Perez, Teepakorn Lertwichaikul, Anucha Sathanawongs, Patchara Pornnimitra, Chanakan Areewong, Jarawee Supanta, Veerasak Punyapornwithaya, Songphon Buddhasiri, Khanittha Punturee
Summary: The Bengal tiger is critically endangered, so artificial insemination is an important conservation tool. This study examined the effects of different voltage electroejaculation protocols on semen quality and animal wellbeing in Bengal tigers. The results suggest that the medium voltage protocol produces good quality samples with lower muscle damage, which is better for animal welfare.
Article
Agriculture, Dairy & Animal Science
Worapong Kosaruk, Janine L. Brown, Patcharapa Towiboon, Veerasak Punyapornwithaya, Kidsadagon Pringproa, Chatchote Thitaram
Summary: This study examined the effects of age, sex, sampling season, and disease factors on various serum oxidative status markers and stress biomarker in captive Asian elephants in Thailand. Age and season were found to have an influence on several biomarkers, while sex did not. Elephant endotheliotropic herpesvirus hemorrhagic disease was associated with significant changes in oxidative stress markers.
Article
Agriculture, Dairy & Animal Science
Paramintra Vinitchaikul, Veerasak Punyapornwithaya, Suvaluk Seesupa, Sitthinon Phuykhamsingha, Orapun Arjkumpa, Chalutwan Sansamur, Chaiwat Jarassaeng
Summary: This study aimed to determine the influence of lumpy skin disease (LSD) outbreaks on monthly milk production levels in the dairy industry in Thailand. The study found that LSD outbreaks had a significant impact on the milk production of dairy farms located in Khon Kaen Province, Thailand, resulting in estimated economic losses of 2,413,000 Thai Baht (68,943 USD) over the outbreak period. The monthly farm milk production level differed in May compared to June and August, and dairy farmers experienced monthly income losses between 4180 and 14,440 Thai Baht (119.43 and 412.57 USD).
Article
Agriculture, Dairy & Animal Science
Pranee Pirompud, Panneepa Sivapirunthep, Veerasak Punyapornwithaya, Chanporn Chaosap
Summary: Knowledge about factors affecting broiler losses during the preslaughter process is limited in Thailand, especially for broilers raised without antibiotics. This study analyzed data from 13,581 truckloads of broilers in 2021 to determine the preslaughter factors influencing dead on arrival (DOA), condemnations, and bruising. Risk factors identified included season, transport time, sex, age at slaughter, mortality and culling rate, and weight per crate. Reducing or eliminating the effects of these factors could improve animal welfare and producer profitability.
Article
Mathematical & Computational Biology
Sompop Moonchai, Adsadang Himakalasa, Thaned Rojsiraphisal, Orapun Arjkumpa, Pawares Panyasomboonying, Noppasorn Kuatako, Noppawan Buamithup, Veerasak Punyapornwithaya
Summary: The study aims to fit the pattern of daily new and cumulative LSD cases in Thailand using mathematical models. The results show that Pearson-type VII and Richard's growth models are more suitable for describing the LSD outbreak. This study provides valuable information for establishing an effective disease control strategy.
INFECTIOUS DISEASE MODELLING
(2023)
Article
Veterinary Sciences
Tawatchai Singhla, Kittikorn Boonsri, Khwanchai Kreausukon, Wittawat Modethed, Kidsadagon Pringproa, Nattawooti Sthitmatee, Veerasak Punyapornwithaya, Paramintra Vinitchaikul
Summary: This study conducted a molecular characterization and phylogenetic analysis of lumpy skin disease virus (LSDV) isolated from dairy cows in northern Thailand. The results showed that the LSDV isolates were closely related to other Asian sequences. Additionally, the LSDV isolates from vaccinated cows clustered with LSDV Neethling-derived vaccines. These findings are important for the development of effective control strategies for LSDV.
VETERINARY SCIENCES
(2022)
Article
Veterinary Sciences
Phurion Chueainta, Veerasak Punyapornwithaya, Weerapongse Tangjitjaroen, Wanpitak Pongkan, Chavalit Boonyapakorn
Summary: This study demonstrated the effectiveness of acupuncture in treating tracheal collapse in small breed dogs. Acupuncture was shown to alleviate clinical signs, reduce oxidative stress, and improve sympathovagal balance.
VETERINARY SCIENCES
(2022)
