期刊
POLYMER CHEMISTRY
卷 8, 期 42, 页码 6520-6526出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7py01408b
关键词
-
资金
- NSFC [51773056, 51373002, 51603067]
- Key Laboratory for High Performance and Functional Polymer Materials of Guangdong Province (South China University of Technology) [20160005]
- State Key Laboratory of Chemo/Biosensing and Chemometrics [2016019, 2013008]
Superior photoswitchable fluorescent polymer nanoparticles (PFPNs) are highly desirable for photo-rewritable data storage and ultrahigh-resolution bioimaging. Herein, 2-(3', 3'-dimethyl-6-nitrospiro [chromene-2,2'-indolin]-1'-yl) ethyl 2-(((dodecylthio)-carbonothioyl) thio)-2-methylpropanoate (SPTTC), a novel photochromic spiropyran-based reversible addition-fragmentation chain transfer (RAFT) reagent, and 5-dimethylaminonaphthalene-N-allyl-1-sulfonamide (DNS), the energy-level matched green fluorescent dye, were firstly synthesized. Then, they are used as donor and acceptor of the designed fluorescence resonance energy transfer (FRET) system to help fabricate superior dual-color PFPNs via a simple one-pot RAFT miniemulsion method. Thanks to its multiple merits such as the photochromic property, improved miscibility, and the ability to control polymerization rate, not only did the designed SPTTC provide the PFPNs with superior photoswitchable fluorescence properties such as high energy transfer efficiency (up to 91%), high dual-color contrast (green and red), rapid photoresponsiveness (2-4 min) and outstanding photoreversibility upon irradiation with UV and visible light, but it also endowed PFPNs with controllable molecular weight and narrow polydispersity index (PDI), excellent cell membrane permeability and long-term fluorescence stability. Moreover, the as-prepared PFPNs were successfully used for rewritable fluorescence patterning and intracellular dual-color imaging due to its prominent properties.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据