Article
Polymer Science
Yasuhito Suzuki, Takahito Kano, Tsuyoshi Tomii, Nagisa Tsuji, Akikazu Matsumoto
Summary: The physical properties of polymers are significantly affected by relaxation processes. In this study, the two relaxations of fumarate-containing polymers were investigated using DSC, solid-state NMR, and X-ray scattering. Even in copolymers, the two relaxations were observed. Tensile tests showed brittleness of PDEF at specific temperatures and structural anisotropy when extended at alpha relaxation temperature.
Article
Chemistry, Multidisciplinary
Maria Cristina Righetti, Maria Laura Di Lorenzo, Patrizia Cinelli, Massimo Gazzano
Summary: The study quantified the temperature evolution of the constrained or rigid amorphous fraction (RAF) of PBS, indicating that at room temperature and at human body temperature, all amorphous fraction is mobile. This information is important for the development of PBS products for various applications.
Article
Pharmacology & Pharmacy
Marcin Skotnicki, Agata Drogon, Janina Lulek, Marek Pyda
Summary: The process of isothermal and non-isothermal physical ageing of amorphous polylactide (PLA) with the active pharmaceutical ingredient, indapamide (IND), was investigated. The PLA-IND system exhibited two glass transitions corresponding to the Tg of PLA and IND, indicating a lack of molecular mixing between the two ingredients. Physical ageing of the PLA-IND system at different temperatures showed that the highest effect was observed at 85 degrees C. The relaxation enthalpies were fitted to the KWW equation to estimate the relaxation time and parameter describing the distribution of relaxation times. The activation energy and fragility parameters of the PLA-IND system were also determined.
Article
Polymer Science
Guanchun Rui, Elshad Allahyarov, John J. Thomas, Philip L. Taylor, Lei Zhu
Summary: A new theoretical approach was developed to determine the dipole characteristics of PVDF using broadband dielectric spectroscopy, revealing an increase in active dipole concentration and mobility as temperature increased. This led to higher permittivity and piezoelectric performance in both unpoled and poled PVDF.
Article
Engineering, Electrical & Electronic
A. A. Kononov, R. A. Castro, Y. Saito, P. Fons, G. A. Bordovsky, N. I. Anisimova, A. V. Kolobov
Summary: Sb2Te3 is a key material in phase-change memory devices and also exhibits topological insulator properties. By studying relaxation processes in thin Sb2Te3 films, it was found that both amorphous and crystalline phases contain two types of relaxators, with one type showing lower relaxation temperature in the amorphous phase. The differences in relaxation mechanisms between the two phases provide insights into the 3D-2D transformation during crystallization of van der Waals solids.
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
(2021)
Article
Polymer Science
Boran Chen, Boxuan Feng, Tong Wang, John M. M. Torkelson
Summary: The study investigated the effect of crystalline fraction (CF) on the rigid amorphous fraction (RAF) in isotactic polystyrene (iPS) samples in both bulk and thin-film states. It was found that RAF in bulk iPS increased and then decreased with increasing crystallization time and CF. Specific RAF, RAF/CF, decreased with increasing CF. Similar behaviors were observed in iPS thin films. The trend of decreasing specific RAF with increasing CF is consistent with crystal perfection and is commonly observed in semi-crystalline polymers.
JOURNAL OF POLYMER SCIENCE
(2023)
Article
Nanoscience & Nanotechnology
Danian Liu, Jingwen Wang, Wenhai Peng, Xinzhu Wang, Hua Ren, Donald W. Kirk
Summary: A semiconductor polyaniline in situ modified rGO nanosheets were proposed to maintain a stable dielectric constant at high frequencies. The pi-pi interface interaction blocked the migration of electrons, resulting in a reduction in relaxation time and a stable dielectric constant. This mechanism has great potential for various high-frequency devices.
ACS APPLIED NANO MATERIALS
(2022)
Article
Chemistry, Physical
Kevin Moch, Philipp Muenzner, Catalin Gainaru, Roland Boehmer
Summary: The study reveals that for propylene glycol, the structural relaxation near the glass transition is more appropriately reflected by the system-dependent susceptibility response recorded by dielectric spectroscopy rather than by the generic response detected by dynamic light scattering. This finding is supported by results from shear rheology and calorimetry.
JOURNAL OF CHEMICAL PHYSICS
(2022)
Article
Polymer Science
Wei Wang, Seif Eddine Fenni, Zhe Ma, Maria Cristina Righetti, Daniele Cangialosi, Maria Laura Di Lorenzo, Dario Cavallo
Summary: The debate on the origin of annealing peaks in semicrystalline polymers continues, with some suggesting they are related to defective/thinner crystals melting, while others propose they are associated with the enthalpy relaxation of the rigid amorphous fraction (RAF) directly coupled to crystalline stems. The study on polymorphic poly (butene-1) (PB-1) shows that the annealing peaks are related to the RAF striving to attain thermodynamic equilibrium in its glassy state within the investigated temperature range.
Article
Polymer Science
Johannes Benz, Christian Bonten
Summary: This study focuses on the impact of fillers on the flow behavior of polymers in plastic processing. By adjusting the composition of the amorphous phase of polymers, it was found that direct interaction between particles leads to changes in flow behavior.
Article
Polymer Science
Mohamed H. Darweesh, Safaa H. El-Taweel, Bernhard Stoll
Summary: The thermal and mechanical properties of binary blends of polypropylene (PP) with a statistical copolymer (VM) were investigated. The two components were found to be miscible in the melt. DSC testing showed that the crystallization temperature of PP decreased with increasing VM content. The measurement of viscoelastic properties revealed a three-phase model, with VM mainly located in the mobile amorphous phase and PP in the rigid amorphous phase.
JOURNAL OF APPLIED POLYMER SCIENCE
(2022)
Article
Polymer Science
Boran Chen, John M. Torkelson
Summary: The study investigates the development of rigid amorphous fraction (RAF) in semi-crystalline syndiotactic polystyrene (sPS) with increasing crystallinity or crystalline fraction (CF) through cold-crystallization procedures. It is observed that as CF increases during cold-crystallization, RAF decreases, indicating an increase in crystal perfection and decoupling between amorphous and crystalline regions. Additionally, the effects of sPS polymorphism on RAF, specifically the alpha form exhibiting higher specific RAF compared to the beta form at a given CF, are briefly considered.
Article
Materials Science, Ceramics
Siyao Chen, Taijun He, Yongjiu Li, Xin Li, Yongbing Zhuang, Xu Wang, Yang Liu, Xiangyang Liu
Summary: This study presents a surface modification method utilizing direct fluorination with F2/N2 to improve the microwave dielectric performance of nano-silica. The direct fluorination effectively reduces the dielectric constant and loss of nano-silica in the microwave band and enhances its dispersibility and compatibility in the polyimide matrix. The resulting PI/F-SiO2 composite film exhibits low dielectric constant, low loss, improved thermal-dimensional stability, and mechanical properties.
CERAMICS INTERNATIONAL
(2023)
Article
Biochemistry & Molecular Biology
Jung H. Lee, Jean-Mathieu Pin, Ruosong Li, Patrick C. Lee, Chul B. Park, S. Hassan Mahmood
Summary: Due to phase heterogeneity in semi-crystalline polymers, accurately determining gas solubility has been challenging. This study used PLA/CO2 as a case study to investigate the parameters influencing the formation of the rigid amorphous fraction (RAF) and its impact on the gas sorption behavior of the polymer.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Chemistry, Physical
Subir Kumar Patla, Pulak Pal, Aswini Ghosh
Summary: We studied the ion transport and segmental dynamics in solid polymer electrolytes based on poly(ethylene oxide) (PEO) and sodium tetrafluoroborate (NaBF4) salt. The molecular weight of PEO polymer matrix was varied while keeping the salt concentration fixed. The ionic conductivity showed correlation with glass transition temperature, crystallinity, and ion diffusion coefficient. AC conductivity spectra were analyzed using a universal power law model, except for the low frequency region where electrode polarization dominated. The temperature dependence of ionic conductivity and hopping frequency followed the Vogel-Tammann-Fulcher (VTF) relation, indicating coupling between ion transport and polymer chain dynamics. The ion transport in PEO based polymer electrolytes with higher molecular weight was found to be more cooperative.
SOLID STATE IONICS
(2023)
Article
Materials Science, Composites
Panayiotis Ketikis, Efthimios Damopoulos, Georgios Pilatos, Panagiotis Klonos, Apostolos Kyritsis, Petroula A. Tarantili
Summary: The impact of graphene nanoplatelets (GN) on hydroxyl-terminated poly(dimethylsiloxane) (PDMS) matrices was investigated, revealing improvements in viscosity, thermal stability, tensile strength, and conductivity, along with reductions in toluene-swelling and oxygen permeability. The incorporation of GN was found to enhance the properties of the composites significantly.
JOURNAL OF COMPOSITE MATERIALS
(2022)
Article
Polymer Science
Katerina Mavronasou, Alexandra Zamboulis, Panagiotis Klonos, Apostolos Kyritsis, Dimitrios N. Bikiaris, Raffaello Papadakis, Ioanna Deligkiozi
Summary: A series of N-methyl quaternized derivatives of poly(4-vinylpyridine) (PVP) were synthesized and their impact on the physicochemical properties of the copolymers, especially solvation properties, was studied. The optical properties of the polymers and their solvation properties in binary solvent mixtures were also investigated. The study provides a better understanding of the key polymer-solvent interactions and the correlation between the degree of quaternization and optical properties.
Article
Polymer Science
Panagiotis A. Klonos, Nikolaos D. Bikiaris, Evi Christodoulou, Alexandra Zamboulis, George Z. Papageorgiou, Apostolos Kyritsis
Summary: In this study, the effects of molecular weight on the crystallization and molecular dynamics of poly(epsilon-caprolactone) (PCL) were investigated. Lower molecular weight samples exhibited greater influence on crystallization, while higher molecular weight samples were dominated by chain-chain entanglements and affected crystal structure formation. The findings are important for tuning the properties of PCL in various applications, particularly in the biomedical and packaging fields.
Article
Chemistry, Multidisciplinary
George Z. Papageorgiou, George N. Nikolaidis, Rafael O. Ioannidis, Konstantinos Rinis, Dimitrios G. Papageorgiou, Panagiotis A. Klonos, Dimitris S. Achilias, Maria Kapnisti, Zoi Terzopoulou, Dimitrios N. Bikiaris
Summary: Three samples of biobased PEF with different molecular weights were synthesized and their crystallization behavior was studied using various techniques. The results showed that the rate of isothermal crystallization decreased with increasing molecular weight. Multiple melting endotherms were observed in the DSC heating thermograms, which could be attributed to recrystallization/reorganization phenomena. By combining the results from different techniques, a better understanding of the crystallization and melting of thermoplastics was achieved.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2022)
Article
Biochemistry & Molecular Biology
Panagiotis A. Klonos, Alexandra Evangelopoulou, Zoi Terzopoulou, Alexandra Zamboulis, Miguel Angel Valera, Ana Mangas, Apostolos Kyritsis, Dimitrios N. Bikiaris
Summary: This work investigates the molecular mobility in renewable block copolymers and the non-trivial effects resulting from crystallization. Various tests were conducted to evaluate the overall thermal behavior, semicrystalline morphology, and molecular mobility under different thermal treatments. The results show that crystallization leads to increased molecular dynamics and suppressed cooperativity, and the impact is stronger in the cold-crystallization process compared to the melt-crystallization process.
Article
Polymer Science
Panagiotis A. Klonos, Maria Lazaridou, Christina Samiotaki, Apostolos Kyritsis, Dimitrios N. Bikiaris
Summary: This study investigates the thermal transitions, crystallization, and molecular mobility of a series of sustainable polymeric blends based on poly(lactic acid) (PLA) and poly(ethylene adipate) (PEAd). The addition of PEAd to PLA enhances the plasticization of PLA chains and facilitates the nucleation of PLA, leading to strong cold crystallization. The blends also exhibit partially miscible polymers and systematic alternation in both local dynamics and dielectric strength. These PLA/PEAd blends have the potential to be used as phase change materials for tuning material performance.
Article
Thermodynamics
Panagiotis A. Klonos, Evi Christodoulou, Theodora C. Katsika, Chrysanthi Papoulia, Konstantinos Chrissafis, Apostolos Kyritsis, Dimitrios N. Bikiaris
Summary: This study investigates the direct and indirect effects of silica nanoparticles on the molecular mobility and crystallization of polymer nanocomposites based on polylactide. The introduction of nanoparticles results in the formation of interfacial interactions and a moderate increase in the glass transition temperature. Crystallinity is suppressed and more active nuclei are observed in the nanocomposites. The slower diffusion of chains related to the nanoparticle-polymer interaction leads to slower crystal growth around more polymer nuclei in the nanocomposites. Local dynamics are affected by the suppression of interfacial interactions and sensitivity to large scale phase changes.
JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
(2022)
Article
Materials Science, Composites
P. Ketikis, I Ketikis, P. A. Klonos, T. Giannakopoulou, A. Kyritsis, C. Trapalis, P. A. Tarantili
Summary: Multiwalled carbon nanotubes (MWCNTs) were mixed with EPDM to form composites using an internal mixer. The structure of CNTs was slightly deteriorated due to the intensive mixing conditions. The thermal stability of the composites was improved, but the glass transition temperature remained unaffected. The composites also showed improved elasticity, reduced swelling, and enhanced electromagnetic interference shielding effectiveness.
JOURNAL OF COMPOSITE MATERIALS
(2023)
Article
Polymer Science
Maria Lazaridou, Panagiotis A. Klonos, Eleni D. Barmpa, Apostolos Kyritsis, Dimitrios N. Bikiaris
Summary: This study investigates polymer blends based on poly(lactic acid) (PLA) and poly(3,3-ethylene dithiodipropionate) (PEDPA) using various experimental techniques. Partial miscibility between the polymers is observed, with well-dispersed PEDPA/PLA structures in the PLA matrix. The crystallization of PLA is suppressed in the blends, while the melting behavior of PEDPA improves slightly.
Article
Polymer Science
Johan Stanley, Zoi Terzopoulou, Panagiotis A. Klonos, Alexandra Zamboulis, Eleftheria Xanthopoulou, Savvas Koltsakidis, Dimitrios Tzetzis, Lidija Fras Zemljic, Dimitra A. Lambropoulou, Apostolos Kyritsis, George Z. Papageorgiou, Dimitrios N. Bikiaris
Summary: This research aims to produce high molecular weight bio-based poly(ethylene furanoate) (PEF) using 2,5-furan dicarboxylic acid (FDCA) or its derivative dimethyl 2,5-furan dicarboxylate (DMFD) for food packaging applications. The study evaluated the influence of monomer type, molar ratios, catalyst, polycondensation time, and temperature on the synthesized samples' intrinsic viscosities and color intensity. FDCA was found to be more effective than DMFD in producing PEF with higher molecular weight. A combination of techniques was used to investigate the structure-properties relationships of the prepared PEF samples in amorphous and semicrystalline states.
Article
Polymer Science
Katerina Papadopoulou, Panagiotis A. A. Klonos, Apostolos Kyritsis, Ondrej Masek, Christian Wurzer, Konstantinos Tsachouridis, Antonios D. D. Anastasiou, Dimitrios N. N. Bikiaris
Summary: Biodegradable polymers, such as poly(butylene succinate) (PBSu) biocomposites, containing biochar (BC) filler can improve mechanical properties, thermal transitions, and biodegradability. The addition of BC enhances tensile and impact strengths, facilitates crystallization, and increases thermal diffusivity and conductivity. However, it also causes an increase in overall dielectric permittivity. Furthermore, the enzymatic hydrolysis degradation rate of biocomposites is found to increase with increasing BC content.
Article
Pharmacology & Pharmacy
Evangelia Balla, Alexandra Zamboulis, Panagiotis Klonos, Apostolos Kyritsis, Panagiotis Barmpalexis, Dimitrios N. Bikiaris
Summary: Novel interpenetrated networks (IPNs) of [2-(methacryloyloxy)ethyl]dimethyl-(3-sulfopropyl)ammonium hydroxide) (SBMA) and poly(vinyl alcohol) (PVA) were prepared for ocular coadministration of timolol maleate (TIM) and dorzolamide hydrochloride (DORZ), both widely used for glaucoma treatment. The IPNs showed significant hydrophilicity and antimicrobial properties, making them suitable for ocular applications. The drug-loaded IPNs exhibited sustained release patterns primarily controlled by diffusion, and were safe for ophthalmic use.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2023)
Article
Chemistry, Physical
Panagiotis A. Klonos, Nikolaos D. Bikiaris, Alexandra Zamboulis, Miguel angel Valera, Ana Mangas, Apostolos Kyritsis, Zoi Terzopoulou
Summary: Two series of sustainable block copolymers based on poly(butylene succinate) (PBSu) and polylactide (PLA) were studied. The effects of PBSu/PLA ratio, chain length, and initial PBSu length on thermal transitions and crystallization of copolymers were investigated. The addition of PBSu improved the performance and degradability of the copolymers, as observed through calorimetry and dielectric spectroscopy.
Article
Chemistry, Physical
Chaima Bouyahya, Nikolaos D. Bikiaris, Alexandra Zamboulis, Apostolos Kyritsis, Mustapha Majdoub, Panagiotis A. Klonos
Summary: In this study, the properties of PCL/PIS block copolymers were investigated using various techniques. It was found that the amorphous PIS phase in the copolymers promoted the crystallization of the majority PCL phase. The study also revealed changes in molecular mobility and cooperativity of the polymer chains in PCL and PCL/PIS systems, as well as the inability to resolve relaxation processes of the initial PIS in the copolymers.
Article
Chemistry, Physical
Panagiotis A. Klonos, Zoi Terzopoulou, Alexandra Zamboulis, Miguel Angel Valera, Ana Mangas, Apostolos Kyritsis, Polycarpos Pissis, Dimitrios N. Bikiaris
Summary: In this study, sustainable block copolymers based on polylactide (PLA) and poly(propylene adipate) (PPAd) were synthesized from renewable resources. The addition of PPAd resulted in a decrease in glass transition and melting temperatures of PLA, as well as facilitated enzymatic degradation and compostability. The molecular mobility and crystallization behavior of the copolymers were investigated, revealing faster polymer chain diffusion and lower crystallization temperatures in the presence of PPAd. The findings suggest the potential of these materials for applications in green packaging and circular economy.
Article
Polymer Science
Yuanzhang Jiang, Xuyi Wang, Yanting Han, Dakai Gong, Yingchun Gu, Lin Tan
Summary: In this study, FeCl3 and poly(acrylic acid) (PAA) were doped into waterborne polyurethanes (WPUs) to create multifunctional materials with self-healing and antimicrobial properties. WPU/Fe/PAA-5.5, containing 5.5 wt % PAA, exhibited excellent mechanical properties, strong self-healing capabilities, and an impressive antimicrobial rate of over 90%. These supramolecular films were also highly recyclable through hot-pressing.
Article
Polymer Science
Longyu Tian, Min Wang, Guangming Liao, Baoliang Liu, Sujuan Zhang, Yucheng Sun, Zhen Meng, Jintao Zhang, Zaijun Lu
Summary: Two kinds of benzoxazine monomers were synthesized and used to prepare polybenzoxazine anion exchange membranes (AEMs) with quaternary ammonium functionalization. The LQPBZ AEM exhibited better ion conductivity and alkaline stability.
Article
Polymer Science
Claire A. Lemarchand
Summary: This study investigates the shock behavior of three different polymers through molecular dynamics simulations. The results reveal specificities in the shock behavior of polymers, including deviations from the linear relation between shock velocity and particle velocity, as well as differences in shear stress relaxation behind the shock front. It is found that the deviation of the Hugoniot locus is related to the change in the relative contribution of bonding and non-bonding potential energies, while polymers with higher glass transition temperatures exhibit slower shear stress relaxation.
Article
Polymer Science
Zengquan Liu, Xiaochun Yin, He Zhang, Shuo Gao, Qinglin Kuang, Yanhong Feng
Summary: A powder solid-state extension (PSSE) technology was proposed to address the high melt viscosity issue of UHMWPE. By uniaxial extension and sintering in the solid state, a highly self-reinforced material was prepared. X-ray diffraction and scattering techniques were used to study the structural evolution during the PSSE process, and a solid-phase induced transformation model was established.
Article
Polymer Science
Zhike Li, Anyu Luo, Rui Zhou, Xin Li, Haiyan Li
Summary: A novel high temperature resistance IL@SiO2 nanocapsules were successfully prepared and their friction and wear properties in PA6 composites were studied. The addition of IL@SiO2 nanocapsules reduced the friction coefficient and wear rate without affecting the mechanical properties of PA6. The synergy between the IL core and SiO2 wall in the nanocapsules improved the self-lubricating performance of the PA6 composites.
Article
Polymer Science
Xin Liu, Xuhong Guo, Qi Liao
Summary: In this study, an algorithm for accurately estimating viscosity is developed using molecular dynamics simulations and the Green-Kubo formula. This algorithm can be applied to complex systems with long correlations, such as macromolecular and biological simulation systems.
Article
Polymer Science
Hao Pu, Yun-Lei Hou, Jing -Zhou Chen, Dong -Lin Zhao
Summary: The use of modified graphene improves the interfacial adherence of carbon fibers to epoxy resin, resulting in enhanced interfacial and bending properties of CF and matrix in CF/EP composites, as well as increased interlaminar shear strength and flexural strength.
Article
Polymer Science
Wei-Chung Ke, Jin-Wei Lin, Manohar Reddy Busireddy, Yueh-Hsing Lee, Jiun-Tai Chen, Chain-Shu Hsu
Summary: This study introduces a crosslinkable monomer, TAIC, to synthesize three crosslinked polyimide films, which exhibit improved thermal, mechanical, and dielectric properties. The introduction of TAIC enhances the tensile strength, reduces the dielectric constant and dielectric loss, and decreases the coefficient of thermal expansion of the polyimide films.
Article
Polymer Science
Alex Kwasi Kumi, Ruiling Fan, Ye Chen, Yumei Zhang
Summary: The difference in leaching of amylopectin from cellulose/amylopectin/1-butyl-3-methylimidazolium chloride ([Bmim][Cl]) blends during regeneration in water and aqueous ethanol has been studied. Molecular dynamics simulations showed that the dissolution and regeneration mechanisms of amylopectin in [Bmim][Cl] are similar to cellulose in ionic liquids. Water regeneration leads to weak electrostatic interactions, resulting in high leaching of amylopectin. In contrast, ethanol-water interactions enhance electrostatic interactions among amylopectin chains, limiting amylopectin leaching in aqueous ethanol.
Article
Polymer Science
Xi Zeng, Junwei Zhou, Junbiao Peng, Chunsheng Zhang, Danling Wang, Yihu Song, Qiang Zheng
Summary: This study utilizes an oligomer deep eutectic solvent (DES) based on polyethylene glycol to regulate the vulcanization kinetics of rubber. The results show that the DES can accelerate vulcanization at low temperatures without affecting the crosslinking density and Mullins effect.
Article
Polymer Science
Qianqian Yue, Yongfei Peng, Xingjian Liu, Aihua He, Huarong Nie
Summary: The addition of metal deactivators can effectively suppress the aging of TBIR, prolong its lifespan, and have no negative effects on its physical and processing properties. These research findings are of great importance for improving the stability and aging resistance of polymers.
Article
Polymer Science
J. Gomez-Caturla, J. Ivorra-Martinez, R. Tejada-Oliveros, V Moreno, D. Garcia-Garcia, R. Balart
Summary: This work focuses on the development of environmentally friendly PLA formulations by using different esters derived from geraniol as plasticizers. The results show that these esters have good compatibility with PLA, and they can effectively enhance the elongation and plasticity of PLA, reduce its glass transition temperature, and slightly improve its water absorption capabilities.
Article
Polymer Science
Dandan Li, Zhaohui Lu, Zhao Ke, Ke Xu, Fengna Dai, Youhai Yu, Guangtao Qian, Chunhai Chen
Summary: In this study, cross-linked PI aerogel membranes with low dielectric constant and high moisture resistance were prepared by co-polymerization and scraping coating technology. The incorporation of fluorinated blocks and benzimidazole ring structures resulted in novel PI aerogel membranes with fascinating dielectric properties and outstanding moisture resistance.
Article
Polymer Science
Zhaoyang Chu, Qing Zhang, Haihua Luo, Han Zhou, Fapei Zhang, Wei Chen, Wenhua Zhang
Summary: Multi-physical fields solution processing strategy is a universal and facile method for preparing various conjugated polymer films and high-performance devices. In this study, we employed a combined microfluidic flow and ultrasonication strategy (FU) for processing CP solutions, and found a pronounced synergetic effect in promoting the pre-ordering of chains in solution. The conformation order and anisotropy of the solution were revealed through various characterizations. A non-classical nucleation model for polymer crystallization in non-equilibrium solution processing was confirmed. The roles of microfluidic flow and ultrasonication in chain aggregation and crystallization were addressed through multi-physical simulations. Compared to pristine solutions, the FU strategy showed improved solution anisotropy and crystallization kinetics, resulting in higher crystallinity in films and increased mobilities in OFET devices. The FU processing strategy provides a universal approach for regulating chain conformation and aggregation in conjugated polymer solutions.