Arachidonic acid containing phosphatidylcholine increases due to microglial activation in ipsilateral spinal dorsal horn following spared sciatic nerve injury

Increased arachidonic acid-containing phosphatidylcholine is associated with reactive microglia and astrocytes in the spinal cord after peripheral nerve injury

(2016) Dongmin Xu et al.   Scientific Reports

Reduction of Neuropathic and Inflammatory Pain through Inhibition of the Tetrahydrobiopterin Pathway

(2015) Alban Latremoliere et al.   NEURON

Network-based proteomic approaches reveal the neurodegenerative, neuroprotective and pain-related mechanisms involved after retrograde axonal damage

(2015) Caty Casas et al.   Scientific Reports

Proteomics of Neuropathic Pain: Proteins and Signaling Pathways Affected in a Rat Model

(2014) Ping Sui et al.   JOURNAL OF PROTEOME RESEARCH

Blockade of IL-6 signaling by MR16-1 inhibits reduction of docosahexaenoic acid-containing phosphatidylcholine levels in a mouse model of spinal cord injury

(2014) H. Arima et al.   NEUROSCIENCE

Astrocyte–neuron interplay in maladaptive plasticity

(2014) Michele Papa et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

DHA-PC and PSD-95 decrease after loss of synaptophysin and before neuronal loss in patients with Alzheimer's disease

(2014) Dai Yuki et al.   Scientific Reports

Time-of-Flight Secondary Ion Mass Spectrometry Based Molecular Histology of Human Spinal Cord Tissue and Motor Neurons

(2013) Jörg Hanrieder et al.   ANALYTICAL CHEMISTRY

Inhibitors of the Arachidonic Acid Cascade: Interfering with Multiple Pathways

(2013) Karin Meirer et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Importance of glial activation in neuropathic pain

(2013) Joanna Mika et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

COX-1-dependent prostaglandin D2 in microglia contributes to neuropathic pain via DP2 receptor in spinal neurons

(2013) Hirosato Kanda et al.   GLIA

A novel biological role for the phospholipid lysophosphatidylinositol in nociceptive sensitization via activation of diverse G-protein signalling pathways in sensory nerves in vivo

(2013) Vijayan Gangadharan et al.   PAIN

Lysophosphatidylcholine causes neuropathic pain via the increase of neuronal nitric oxide synthase in the dorsal root ganglion and cuneate nucleus

(2013) Hsin-Ying Wang et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Spatiotemporal alteration of phospholipids and prostaglandins in a rat model of spinal cord injury

(2012) Mitsuru Hanada et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Lysophosphatidic acid: Chemical signature of neuropathic pain

(2012) Hiroshi Ueda et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

P2X4R+ microglia drive neuropathic pain

(2012) Simon Beggs et al.   NATURE NEUROSCIENCE

Systems wide analyses of lipids in the brainstem during inflammatory orofacial pain - Evidence of increased phospholipase A2 activity

(2011) M.-T. Ma et al.   EUROPEAN JOURNAL OF PAIN

Axonal Gradient of Arachidonic Acid-containing Phosphatidylcholine and Its Dependence on Actin Dynamics

(2011) Hyun-Jeong Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A thickening network of lipids

(2011) Daniele Piomelli   PAIN

Multiple chronic pain states are associated with a common amino acid–changing allele in KCNS1

(2010) Michael Costigan et al.   BRAIN

Neuronal circuitry for pain processing in the dorsal horn

(2010) Andrew J. Todd   NATURE REVIEWS NEUROSCIENCE

Reactive astrocytosis-induced perturbation of synaptic homeostasis is restored by nerve growth factor

(2010) Giovanni Cirillo et al.   NEUROBIOLOGY OF DISEASE

Imaging mass spectrometry revealed the production of lyso-phosphatidylcholine in the injured ischemic rat brain

(2010) S. Koizumi et al.   NEUROSCIENCE

Cellular and Molecular Mechanisms of Pain

(2009) Allan I. Basbaum et al.   CELL

Spinal Endocannabinoids and CB1 Receptors Mediate C-Fiber-Induced Heterosynaptic Pain Sensitization

(2009) A. J. Pernia-Andrade et al.   SCIENCE

Minocycline prevents the development of neuropathic pain, but not acute pain: Possible anti-inflammatory and antioxidant mechanisms

(2008) Satyanarayana S.V. Padi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Direct profiling of tissue lipids by MALDI-TOFMS

(2008) Shelley N. Jackson et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Pathological and protective roles of glia in chronic pain

(2008) Erin D. Milligan et al.   NATURE REVIEWS NEUROSCIENCE

Low-dose methotrexate reduces peripheral nerve injury-evoked spinal microglial activation and neuropathic pain behavior in rats

(2008) Joachim Scholz et al.   PAIN