Imaging extracellular ATP with a genetically-encoded, ratiometric fluorescent sensor

Blocking microglial pannexin-1 channels alleviates morphine withdrawal in rodents

(2017) Nicole E Burma et al.   NATURE MEDICINE

Use of luciferase probes to measure ATP in living cells and animals

(2017) Giampaolo Morciano et al.   Nature Protocols

Glia-derived ATP inversely regulates excitability of pyramidal and CCK-positive neurons

(2017) Zhibing Tan et al.   Nature Communications

Imaging Adenosine Triphosphate (ATP)

(2016) Megha Rajendran et al.   BIOLOGICAL BULLETIN

Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance

(2016) Federico Pietrocola et al.   CANCER CELL

Purinergic receptor P2RY12-dependent microglial closure of the injured blood–brain barrier

(2016) Nanhong Lou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diadenosine tetraphosphate (Ap4A) inhibits ATP-induced excitotoxicity: a neuroprotective strategy for traumatic spinal cord injury treatment

(2016) David Reigada et al.   Purinergic Signalling

Nanobodies that block gating of the P2X7 ion channel ameliorate inflammation

(2016) W. Danquah et al.   Science Translational Medicine

Sensitive red protein calcium indicators for imaging neural activity

(2016) Hod Dana et al.   eLife

Extracellular Metabolic Energetics Can Promote Cancer Progression

(2015) Jia Min Loo et al.   CELL

Inhibitory effect of caffeic acid on ADP-induced thrombus formation and platelet activation involves mitogen-activated protein kinases

(2015) Yu Lu et al.   Scientific Reports

Mitochondria Regulate Neutrophil Activation by Generating ATP for Autocrine Purinergic Signaling

(2014) Yi Bao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondria Are Gate-keepers of T Cell Function by Producing the ATP That Drives Purinergic Signaling

(2014) Carola Ledderose et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nucleotide signalling during inflammation

(2014) Marco Idzko et al.   NATURE

Optimized ratiometric calcium sensors for functional in vivo imaging of neurons and T lymphocytes

(2014) Thomas Thestrup et al.   NATURE METHODS

Rational design of a high-affinity, fast, red calcium indicator R-CaMP2

(2014) Masatoshi Inoue et al.   NATURE METHODS

Gliotransmitters Travel in Time and Space

(2014) Alfonso Araque et al.   NEURON

ATP P2X Receptors Downregulate AMPA Receptor Trafficking and Postsynaptic Efficacy in Hippocampal Neurons

(2014) Johan-Till Pougnet et al.   NEURON

A long Stokes shift red fluorescent Ca2+ indicator protein for two-photon and ratiometric imaging

(2014) Jiahui Wu et al.   Nature Communications

P2Y Receptor Modulation of ATP Release in the Urothelium

(2014) Kylie J. Mansfield et al.   Biomed Research International

Inhibition of CD39 Enzymatic Function at the Surface of Tumor Cells Alleviates Their Immunosuppressive Activity

(2014) J. Bastid et al.   Cancer Immunology Research

Single Cell Amperometry Reveals Glycocalyx Hinders the Release of Neurotransmitters During Exocytosis

(2013) Raphaël Trouillon et al.   ANALYTICAL CHEMISTRY

ATP increases within the lumen of the endoplasmic reticulum upon intracellular Ca2+ release

(2013) Neelanjan Vishnu et al.   MOLECULAR BIOLOGY OF THE CELL

Ultrasensitive fluorescent proteins for imaging neuronal activity

(2013) Tsai-Wen Chen et al.   NATURE

An optimized fluorescent probe for visualizing glutamate neurotransmission

(2013) Jonathan S Marvin et al.   NATURE METHODS

Purinergic signalling and cancer

(2013) Geoffrey Burnstock et al.   Purinergic Signalling

Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogenetics

(2013) Jasper Akerboom et al.   Frontiers in Molecular Neuroscience

P2X7 receptor-stimulation causes fever via PGE2 and IL-1β release

(2012) Maria Barberà-Cremades et al.   FASEB JOURNAL

Organelle-Localizable Fluorescent Chemosensors for Site-Specific Multicolor Imaging of Nucleoside Polyphosphate Dynamics in Living Cells

(2012) Yasutaka Kurishita et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pannexin1-Mediated ATP Release Provides Signal Transmission Between Neuro2A Cells

(2012) Rodolfo M. Iglesias et al.   NEUROCHEMICAL RESEARCH

Neuromodulation by Extracellular ATP and P2X Receptors in the CNS

(2012) Baljit S. Khakh et al.   NEURON

Purinergic Signaling during Inflammation

(2012) Holger K. Eltzschig et al.   NEW ENGLAND JOURNAL OF MEDICINE

Neuronal adenosine release, and not astrocytic ATP release, mediates feedback inhibition of excitatory activity

(2012) D. Lovatt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vesicular and conductive mechanisms of nucleotide release

(2012) Eduardo R. Lazarowski   Purinergic Signalling

Extracellular Ca2+ Acts as a Mediator of Communication from Neurons to Glia

(2012) A. Torres et al.   Science Signaling

P2X7 Receptors Trigger ATP Exocytosis and Modify Secretory Vesicle Dynamics in Neuroblastoma Cells

(2011) Yolanda Gutiérrez-Martín et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Imaging Intracellular pH in Live Cells with a Genetically Encoded Red Fluorescent Protein Sensor

(2011) Mathew Tantama et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Quantitative Glucose and ATP Sensing in Mammalian Cells

(2011) Dania C. Liemburg-Apers et al.   PHARMACEUTICAL RESEARCH

Activation and Regulation of Purinergic P2X Receptor Channels

(2011) C. Coddou et al.   PHARMACOLOGICAL REVIEWS

Dynamic Changes in the MicroRNA Expression Profile Reveal Multiple Regulatory Mechanisms in the Spinal Nerve Ligation Model of Neuropathic Pain

(2011) David von Schack et al.   PLoS One

An Expanded Palette of Genetically Encoded Ca2+ Indicators

(2011) Y. Zhao et al.   SCIENCE

Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice

(2011) M. Michaud et al.   SCIENCE

Imaging Single Photons and Intrinsic Optical Signals for Studies of Vesicular and Non-Vesicular ATP Release from Axons

(2011) R. Douglas Fields   Frontiers in Neuroanatomy

Lack of the purinergic receptor P2X7results in resistance to contact hypersensitivity

(2010) Felix C. Weber et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis

(2010) Faraaz B. Chekeni et al.   NATURE

Graft-versus-host disease is enhanced by extracellular ATP activating P2X7R

(2010) Konrad Wilhelm et al.   NATURE MEDICINE

A genetically targeted optical sensor to monitor calcium signals in astrocyte processes

(2010) Eiji Shigetomi et al.   NATURE NEUROSCIENCE

Astrocytes Control Breathing Through pH-Dependent Release of ATP

(2010) A. V. Gourine et al.   SCIENCE

Basal Release of ATP: An Autocrine-Paracrine Mechanism for Cell Regulation

(2010) R. Corriden et al.   Science Signaling

Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance

(2009) Michael R. Elliott et al.   NATURE

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

(2009) François Ghiringhelli et al.   NATURE MEDICINE

A genetically encoded fluorescent reporter of ATP:ADP ratio

(2009) Jim Berg et al.   NATURE METHODS

Visualization of ATP levels inside single living cells with fluorescence resonance energy transfer-based genetically encoded indicators

(2009) H. Imamura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATP release from non-excitable cells

(2009) Helle A. Praetorius et al.   Purinergic Signalling

Imaging Localized Astrocyte ATP Release with Firefly Luciferase Beads Attached to the Cell Surface

(2008) Yun Zhang et al.   ANALYTICAL CHEMISTRY

BM88/Cend1 regulates stimuli-induced intracellular calcium mobilization

(2008) Roser Masgrau et al.   NEUROPHARMACOLOGY

Increased Level of Extracellular ATP at Tumor Sites: In Vivo Imaging with Plasma Membrane Luciferase

(2008) Patrizia Pellegatti et al.   PLoS One

Optical measurement of synaptic glutamate spillover and reuptake by linker optimized glutamate-sensitive fluorescent reporters

(2008) S. A. Hires et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA