How stable is repression of disallowed genes in pancreatic islets in response to metabolic stress?

Disallowed and Allowed Gene Expression: Two Faces of Mature Islet Beta Cells

(2016) Katleen Lemaire et al.   Annual Review of Nutrition

Transcriptomic profiling of pancreatic alpha, beta and delta cell populations identifies delta cells as a principal target for ghrelin in mouse islets

(2016) Alice E. Adriaenssens et al.   DIABETOLOGIA

p16Ink4a-induced senescence of pancreatic beta cells enhances insulin secretion

(2016) Aharon Helman et al.   NATURE MEDICINE

Comprehensive alpha, beta and delta cell transcriptomes reveal that ghrelin selectively activates delta cells and promotes somatostatin release from pancreatic islets

(2016) Michael R. DiGruccio et al.   Molecular Metabolism

Type 2 Diabetes and the Aging Pancreatic Beta Cell

(2016) Uma Gunasekaran et al.   Aging-US

High-fat diet-induced β-cell proliferation occurs prior to insulin resistance in C57Bl/6J male mice

(2015) Rockann E. Mosser et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Aging-Dependent Demethylation of Regulatory Elements Correlates with Chromatin State and Improved β Cell Function

(2015) Dana Avrahami et al.   Cell Metabolism

DNA methylation directs functional maturation of pancreatic β cells

(2015) Sangeeta Dhawan et al.   JOURNAL OF CLINICAL INVESTIGATION

MafA is critical for maintenance of the mature beta cell phenotype in mice

(2014) Wataru Nishimura et al.   DIABETOLOGIA

Young capillary vessels rejuvenate aged pancreatic islets

(2014) Joana Almaça et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rfx6 Maintains the Functional Identity of Adult Pancreatic β Cells

(2014) Julie Piccand et al.   Cell Reports

The role of aging upon β cell turnover

(2013) Jake A. Kushner   JOURNAL OF CLINICAL INVESTIGATION

Regulation of Insulin Secretion in Human Pancreatic Islets

(2012) Patrik Rorsman et al.   Annual Review of Physiology

Pancreatic β Cell Dedifferentiation as a Mechanism of Diabetic β Cell Failure

(2012) Chutima Talchai et al.   CELL

Overexpression of Monocarboxylate Transporter-1 (Slc16a1) in Mouse Pancreatic  -Cells Leads to Relative Hyperinsulinism During Exercise

(2012) T. J. Pullen et al.   DIABETES

β-Cell–Specific Gene Repression: A Mechanism to Protect Against Inappropriate or Maladjusted Insulin Secretion?

(2012) Frans Schuit et al.   DIABETES

Ring1b bookmarks genes in pancreatic embryonic progenitors for repression in adult   cells

(2012) J. van Arensbergen et al.   GENES & DEVELOPMENT

mRNA expression analysis of cell cycle genes in islets of pregnant mice

(2010) A. Schraenen et al.   DIABETOLOGIA

Placental lactogens induce serotonin biosynthesis in a subset of mouse beta cells during pregnancy

(2010) A. Schraenen et al.   DIABETOLOGIA

Mafa expression enhances glucose-responsive insulin secretion in neonatal rat beta cells

(2010) C. Aguayo-Mazzucato et al.   DIABETOLOGIA

Tissue-specific disallowance of housekeeping genes: The other face of cell differentiation

(2010) L. Thorrez et al.   GENOME RESEARCH

Derepression of Polycomb targets during pancreatic organogenesis allows insulin-producing beta-cells to adopt a neural gene activity program

(2010) J. van Arensbergen et al.   GENOME RESEARCH

Rfx6 directs islet formation and insulin production in mice and humans

(2010) Stuart B. Smith et al.   NATURE

Serotonin regulates pancreatic beta cell mass during pregnancy

(2010) Hail Kim et al.   NATURE MEDICINE

Downregulation of ZnT8 expression in pancreatic β-cells of diabetic mice

(2010) Motoyuki Tamaki et al.   Islets

Identification of genes selectively disallowed in the pancreatic islet

(2010) Timothy J. Pullen et al.   Islets

Polycomb protein Ezh2 regulates pancreatic  -cell Ink4a/Arf expression and regeneration in diabetes mellitus

(2009) H. Chen et al.   GENES & DEVELOPMENT

Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice

(2009) K. Lemaire et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expansion of β-cell mass in response to pregnancy

(2009) Sebastian Rieck et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Why expression of some genes is disallowed in β-cells

(2008) Roel Quintens et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

In vivo reprogramming of adult pancreatic exocrine cells to β-cells

(2008) Qiao Zhou et al.   NATURE