Inhibitors of Mycobacterium marinum virulence identified in a Dictyostelium discoideum host model

The Carbonic Anhydrase Inhibitor Ethoxzolamide Inhibits the Mycobacterium tuberculosis PhoPR Regulon and Esx-1 Secretion and Attenuates Virulence

(2015) Benjamin K. Johnson et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

CpsA, a LytR-CpsA-Psr Family Protein in Mycobacterium marinum, Is Required for Cell Wall Integrity and Virulence

(2015) Qinglan Wang et al.   INFECTION AND IMMUNITY

Pentapeptide boronic acid inhibitors of Mycobacterium tuberculosis MycP1 protease

(2014) Mykhaylo S. Frasinyuk et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Discovery of the first potent and selective Mycobacterium tuberculosis Zmp1 inhibitor

(2014) Mattia Mori et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Anticytolytic Screen Identifies Inhibitors of Mycobacterial Virulence Protein Secretion

(2014) Jan Rybniker et al.   Cell Host & Microbe

Establishment and Validation of Whole-Cell Based Fluorescence Assays to Identify Anti-Mycobacterial Compounds Using the Acanthamoeba castellanii - Mycobacterium marinum Host-Pathogen System

(2014) Sébastien Kicka et al.   PLoS One

The natural alternative: protozoa as cellular models forLegionellainfection

(2013) Christine Hoffmann et al.   CELLULAR MICROBIOLOGY

Exploring Anti-Bacterial Compounds against Intracellular Legionella

(2013) Christopher F. Harrison et al.   PLoS One

Discovery of Mycobacterium tuberculosis Protein Tyrosine Phosphatase B (PtpB) Inhibitors from Natural Products

(2013) Alessandra Mascarello et al.   PLoS One

Resistance in tuberculosis: what do we know and where can we go?

(2013) Keith D. Green et al.   Frontiers in Microbiology

Both Phthiocerol Dimycocerosates and Phenolic Glycolipids Are Required for Virulence of Mycobacterium marinum

(2012) Jia Yu et al.   INFECTION AND IMMUNITY

New Drugs for the Treatment of Tuberculosis: Needs, Challenges, Promise, and Prospects for the Future

(2012) Christian Lienhardt et al.   JOURNAL OF INFECTIOUS DISEASES

Vibrio cholerae Requires the Type VI Secretion System Virulence Factor VasX To Kill Dictyostelium discoideum

(2011) Sarah T. Miyata et al.   INFECTION AND IMMUNITY

PPE38 Modulates the Innate Immune Response and Is Required for Mycobacterium marinum Virulence

(2011) Dandan Dong et al.   INFECTION AND IMMUNITY

A Mycobacterium marinum TesA mutant defective for major cell wall-associated lipids is highly attenuated in Dictyostelium discoideum and zebrafish embryos

(2011) Laeticia Alibaud et al.   MOLECULAR MICROBIOLOGY

Anti-virulence strategies to combat bacteria-mediated disease

(2010) David A. Rasko et al.   NATURE REVIEWS DRUG DISCOVERY

Optimisation of Bioluminescent Reporters for Use with Mycobacteria

(2010) Nuria Andreu et al.   PLoS One

What can Dictyostelium bring to the study of Pseudomonas infections?

(2010) Wanessa C. Lima et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Dictyostelium discoideum: a model host to measure bacterial virulence

(2009) Romain Froquet et al.   Nature Protocols

Autophagy genes protect against Salmonella typhimurium infection and mediate insulin signaling-regulated pathogen resistance

(2009) K. Jia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Infection by Tubercular Mycobacteria Is Spread by Nonlytic Ejection from Their Amoeba Hosts

(2009) M. Hagedorn et al.   SCIENCE

High Content Screening Identifies Decaprenyl-Phosphoribose 2′ Epimerase as a Target for Intracellular Antimycobacterial Inhibitors

(2009) Thierry Christophe et al.   PLoS Pathogens

Pseudomonas aeruginosa virulence genes identified in a Dictyostelium host model

(2008) Laeticia Alibaud et al.   CELLULAR MICROBIOLOGY

Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis

(2008) T. P. Stinear et al.   GENOME RESEARCH